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KLLA0_E04819g KLLA0_E04819g KLLA0_E11045g KLLA0_E11045g KLLA0_E16061g KLLA0_E16061g SNU13 SNU13 KLLA0_C08019g KLLA0_C08019g KLLA0_B11594g KLLA0_B11594g KLLA0_B08976g KLLA0_B08976g KLLA0_B08525g KLLA0_B08525g KLLA0_B02156g KLLA0_B02156g SPT5 SPT5 RSE1 RSE1 KLLA0_A06688g KLLA0_A06688g KLLA0_A05280g KLLA0_A05280g KLLA0_C09801g KLLA0_C09801g NOP58 NOP58 LSM4 LSM4 CWC2 CWC2 KLLA0_E01277g KLLA0_E01277g
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KLLA0_E04819gKLLA0E04819p. (459 aa)
KLLA0_E11045gKLLA0E11045p. (432 aa)
KLLA0_E16061gKLLA0E16061p. (1086 aa)
SNU1313 kDa ribonucleoprotein-associated protein; Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity). (126 aa)
KLLA0_C08019gKLLA0C08019p. (301 aa)
KLLA0_B11594gKLLA0B11594p. (114 aa)
KLLA0_B08976gKLLA0B08976p. (305 aa)
KLLA0_B08525gKLLA0B08525p. (326 aa)
KLLA0_B02156gKLLA0B02156p. (242 aa)
SPT5Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (1036 aa)
RSE1Pre-mRNA-splicing factor RSE1; Involved in pre-mRNA splicing and cell cycle control. (1269 aa)
KLLA0_A06688gKLLA0A06688p. (933 aa)
KLLA0_A05280gKLLA0A05280p. (2411 aa)
KLLA0_C09801gKLLA0C09801p. (588 aa)
NOP58Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family. (511 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (183 aa)
CWC2Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...] (337 aa)
KLLA0_E01277gKLLA0E01277p. (266 aa)
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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