STRINGSTRING
KLLA0_D14883g KLLA0_D14883g KLLA0_D13420g KLLA0_D13420g KLLA0_D09284g KLLA0_D09284g KLLA0_D07678g KLLA0_D07678g KLLA0_D03795g KLLA0_D03795g SNU71 SNU71 KLLA0_C17798g KLLA0_C17798g KLLA0_C15675g KLLA0_C15675g PRP28 PRP28 LSM4 LSM4 KLLA0_F14861g KLLA0_F14861g KLLA0_F09207g KLLA0_F09207g KLLA0_C15169g KLLA0_C15169g KLLA0_C14388g KLLA0_C14388g KLLA0_C08800g KLLA0_C08800g KLLA0_C08019g KLLA0_C08019g KLLA0_A05280g KLLA0_A05280g KLLA0_A04565g KLLA0_A04565g KLLA0_A02299g KLLA0_A02299g KLLA0_C05192g KLLA0_C05192g KLLA0_C02629g KLLA0_C02629g KLLA0_B08976g KLLA0_B08976g KLLA0_B08910g KLLA0_B08910g KLLA0_B05203g KLLA0_B05203g KLLA0_B02156g KLLA0_B02156g KLLA0_B00627g KLLA0_B00627g KLLA0_A09537g KLLA0_A09537g RSE1 RSE1 KLLA0_A08019g KLLA0_A08019g KLLA0_A06688g KLLA0_A06688g KLLA0_F08591g KLLA0_F08591g KLLA0_F07249g KLLA0_F07249g KLLA0_F04191g KLLA0_F04191g KLLA0_E22881g KLLA0_E22881g SNU13 SNU13 KLLA0_E20505g KLLA0_E20505g KLLA0_E18239g KLLA0_E18239g KLLA0_E16457g KLLA0_E16457g KLLA0_E11045g KLLA0_E11045g KLLA0_E10209g KLLA0_E10209g KLLA0_E09285g KLLA0_E09285g KLLA0_E04929g KLLA0_E04929g KLLA0_E04819g KLLA0_E04819g LSM6 LSM6 KLLA0_D17160g KLLA0_D17160g
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KLLA0_D14883gKLLA0D14883p. (467 aa)
KLLA0_D13420gKLLA0D13420p. (166 aa)
KLLA0_D09284gSmall nuclear ribonucleoprotein Sm D2. (110 aa)
KLLA0_D07678gSmall nuclear ribonucleoprotein G. (73 aa)
KLLA0_D03795gKLLA0D03795p. (234 aa)
SNU71U1 small nuclear ribonucleoprotein component SNU71; Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway (By similarity). (568 aa)
KLLA0_C17798gKLLA0C17798p. (2149 aa)
KLLA0_C15675gKLLA0C15675p. (111 aa)
PRP28Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity). (539 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (183 aa)
KLLA0_F14861gKLLA0F14861p. (589 aa)
KLLA0_F09207gU6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
KLLA0_C15169gKLLA0C15169p. (549 aa)
KLLA0_C14388gKLLA0C14388p. (203 aa)
KLLA0_C08800gKLLA0C08800p. (157 aa)
KLLA0_C08019gKLLA0C08019p. (301 aa)
KLLA0_A05280gKLLA0A05280p. (2411 aa)
KLLA0_A04565gKLLA0A04565p. (189 aa)
KLLA0_A02299gSmall nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (93 aa)
KLLA0_C05192gKLLA0C05192p. (189 aa)
KLLA0_C02629gKLLA0C02629p. (325 aa)
KLLA0_B08976gKLLA0B08976p. (305 aa)
KLLA0_B08910gSpliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (143 aa)
KLLA0_B05203gKLLA0B05203p. (83 aa)
KLLA0_B02156gKLLA0B02156p. (242 aa)
KLLA0_B00627gKLLA0B00627p. (191 aa)
KLLA0_A09537gKLLA0A09537p. (954 aa)
RSE1Pre-mRNA-splicing factor RSE1; Involved in pre-mRNA splicing and cell cycle control. (1269 aa)
KLLA0_A08019gKLLA0A08019p. (615 aa)
KLLA0_A06688gKLLA0A06688p. (933 aa)
KLLA0_F08591gKLLA0F08591p. (557 aa)
KLLA0_F07249gKLLA0F07249p. (256 aa)
KLLA0_F04191gKLLA0F04191p. (885 aa)
KLLA0_E22881gKLLA0E22881p. (110 aa)
SNU1313 kDa ribonucleoprotein-associated protein; Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity). (126 aa)
KLLA0_E20505gKLLA0E20505p. (357 aa)
KLLA0_E18239gKLLA0E18239p. (571 aa)
KLLA0_E16457gKLLA0E16457p. (96 aa)
KLLA0_E11045gKLLA0E11045p. (432 aa)
KLLA0_E10209gKLLA0E10209p. (84 aa)
KLLA0_E09285gKLLA0E09285p. (424 aa)
KLLA0_E04929gKLLA0E04929p. (112 aa)
KLLA0_E04819gKLLA0E04819p. (459 aa)
LSM6U6 snRNA-associated Sm-like protein LSm6; Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2- LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 [...] (80 aa)
KLLA0_D17160gSmall nuclear ribonucleoprotein Sm D3. (100 aa)
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
Server load: low (22%) [HD]