(52 nodes) Nuclear pore, and Nucleocytoplasmic carrier activity network (Yarrowia lipolytica)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	YALI0_F24563g	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (708 aa)
	YALI0_F28501g	Importin subunit alpha; Belongs to the importin alpha family. (531 aa)
	YALI0_F28281g	YALI0F28281p. (1097 aa)
	YALI0_F22759g	YALI0F22759p. (660 aa)
	YALI0_F22473g	YALI0F22473p. (460 aa)
	YALI0_F20878g	Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (530 aa)
	YALI0_F20526g	YALI0F20526p. (1939 aa)
	YALI0_F17622g	Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (418 aa)
	YALI0_F14575g	YALI0F14575p. (1091 aa)
	YALI0_F13519g	YALI0F13519p. (1548 aa)
	YALI0_F10098g	YALI0F10098p. (1080 aa)
	DBP5	ATP-dependent RNA helicase DBP5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity). (488 aa)
	YALI0_E29909g	YALI0E29909p. (950 aa)
	YALI0_E23265g	YALI0E23265p. (366 aa)
	YALI0_E16324g	YALI0E16324p. (1040 aa)
	YALI0_E12243g	YALI0E12243p. (1045 aa)
	YALI0_E10901g	YALI0E10901p. (457 aa)
	YALI0_E07139g	YALI0E07139p. (952 aa)
	LOS1	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity); Belongs to the exportin family. (1025 aa)
	YALI0_E02706g	YALI0E02706p. (1399 aa)
	YALI0_E01276g	YALI0E01276p. (1339 aa)
	YALI0_D17886g	YALI0D17886p. (1272 aa)
	YALI0_D15840g	YALI0D15840p. (1120 aa)
	YALI0_D12144g	YALI0D12144p. (865 aa)
	YALI0_D08998g	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (743 aa)
	YALI0_D06820g	YALI0D06820p. (913 aa)
	YALI0_D04444g	YALI0D04444p. (1288 aa)
	YALI0_D03267g	YALI0D03267p; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (495 aa)
	YALI0_C23166g	YALI0C23166p. (456 aa)
	YALI0_C22066g	Nuclear pore protein. (882 aa)
	NTF2	Nuclear transport factor 2; Facilitates protein transport into the nucleus. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity). (123 aa)
	YALI0_C09988g	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (176 aa)
	YALI0_C03850g	YALI0C03850p. (640 aa)
	YALI0_B16610g	YALI0B16610p; Belongs to the WD repeat SEC13 family. (319 aa)
	YALI0_B15081g	YALI0B15081p. (269 aa)
	YALI0_B14971g	YALI0B14971p. (1329 aa)
	YALI0_B14663g	Peptidyl-prolyl cis-trans isomerase. (185 aa)
	YALI0_B12210g	YALI0B12210p. (386 aa)
	YALI0_B11132g	YALI0B11132p. (153 aa)
	YALI0_B05456g	YALI0B05456p. (741 aa)
	YALI0_B02750g	YALI0B02750p. (1653 aa)
	YALI0_B02706g	YALI0B02706p. (535 aa)
	YALI0_B01870g	YALI0B01870p. (619 aa)
	YALI0_B01650g	YALI0B01650p. (143 aa)
	YALI0_B00198g	YALI0B00198p. (971 aa)
	YALI0_A20702g	YALI0A20702p. (528 aa)
	YALI0_A18007g	YALI0A18007p. (531 aa)
	YALI0_A13299g	YALI0A13299p. (498 aa)
	YALI0_A07062g	YALI0A07062p. (323 aa)
	YALI0_A03883g	YALI0A03883p. (1124 aa)
	YALI0_A02134g	YALI0A02134p. (1366 aa)
	GSP1	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). (214 aa)

Your Current Organism:

Yarrowia lipolytica

NCBI taxonomy Id: 284591
Other names: Y. lipolytica CLIB122, Yarrowia lipolytica CLIB122

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DBP5	YALI0_A18007g	Q6C3X7	Q6CGM7	ATP-dependent RNA helicase DBP5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).	YALI0A18007p.	0.743
DBP5	YALI0_B01870g	Q6C3X7	Q6CG09	ATP-dependent RNA helicase DBP5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).	YALI0B01870p.	0.987
DBP5	YALI0_C23166g	Q6C3X7	Q6CAZ4	ATP-dependent RNA helicase DBP5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).	YALI0C23166p.	0.560
DBP5	YALI0_E01276g	Q6C3X7	Q6C7F3	ATP-dependent RNA helicase DBP5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).	YALI0E01276p.	0.992
DBP5	YALI0_E23265g	Q6C3X7	Q6C4W1	ATP-dependent RNA helicase DBP5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).	YALI0E23265p.	0.575
DBP5	YALI0_F10098g	Q6C3X7	Q6C278	ATP-dependent RNA helicase DBP5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).	YALI0F10098p.	0.523
DBP5	YALI0_F28281g	Q6C3X7	Q6C029	ATP-dependent RNA helicase DBP5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).	YALI0F28281p.	0.547
DBP5	YALI0_F28501g	Q6C3X7	Q6C019	ATP-dependent RNA helicase DBP5; ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).	Importin subunit alpha; Belongs to the importin alpha family.	0.417
GSP1	LOS1	Q8TFK3	Q6C715	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity); Belongs to the exportin family.	0.997
GSP1	NTF2	Q8TFK3	Q6CC82	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	Nuclear transport factor 2; Facilitates protein transport into the nucleus. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity).	0.962
GSP1	YALI0_A02134g	Q8TFK3	Q6CI34	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	YALI0A02134p.	0.999
GSP1	YALI0_A03883g	Q8TFK3	Q6CHX1	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	YALI0A03883p.	0.648
GSP1	YALI0_A13299g	Q8TFK3	Q6CH27	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	YALI0A13299p.	0.998
GSP1	YALI0_A20702g	Q8TFK3	Q6CGB3	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	YALI0A20702p.	0.742
GSP1	YALI0_B00198g	Q8TFK3	Q6CG75	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	YALI0B00198p.	0.521
GSP1	YALI0_B02706g	Q8TFK3	Q6CFX8	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	YALI0B02706p.	0.999
GSP1	YALI0_B02750g	Q8TFK3	Q6CFX6	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	YALI0B02750p.	0.606
GSP1	YALI0_B12210g	Q8TFK3	Q6CEX2	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	YALI0B12210p.	0.998
GSP1	YALI0_B14971g	Q8TFK3	Q6CEK4	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	YALI0B14971p.	0.811
GSP1	YALI0_B15081g	Q8TFK3	Q6CEJ9	GTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	YALI0B15081p.	0.997