node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACEB_YARLI | ICL1 | Q6BZP5 | P41555 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | 0.904 |
ACEB_YARLI | PAT1 | Q6BZP5 | Q6L8K7 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acetyl-CoA acetyltransferase; Essential for n-decane utilization. | 0.631 |
ACEB_YARLI | PAY32 | Q6BZP5 | Q99144 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | 0.495 |
ACEB_YARLI | PEX6 | Q6BZP5 | P36966 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Peroxisomal biogenesis factor 6; Involved in peroxisome biosynthesis; Belongs to the AAA ATPase family. | 0.485 |
ACEB_YARLI | POX1 | Q6BZP5 | O74934 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase 1. | 0.696 |
ACEB_YARLI | POX2 | Q6BZP5 | O74935 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase 2; Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group. | 0.726 |
ACEB_YARLI | POX3 | Q6BZP5 | O74936 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase 3; Oxidizes aliphatic acyl-CoA substrates of different chain lengths such as hexanoyl-CoA, decanoyl-CoA and myristoyl-CoA as well as aromatic/heterocyclic ring-substituted chromogenic substrates, such as furylpropionyl-CoA. Of the above substrates, the efficiency of the enzyme, exhibits the following order: decanoyl-CoA > myristoyl-CoA > hexanoyl-CoA > furyl-propionyl-CoA. | 0.613 |
ACEB_YARLI | SEC14 | Q6BZP5 | P45816 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | SEC14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. | 0.551 |
ACEB_YARLI | YALI0_C23859g | Q6BZP5 | F2Z630 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.620 |
ACEB_YARLI | YALI0_E06567g | Q6BZP5 | Q6C6T0 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.634 |
ACEB_YARLI | YALI0_E27654g | Q6BZP5 | F2Z627 | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.623 |
ICL1 | ACEB_YARLI | P41555 | Q6BZP5 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | 2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | 0.904 |
ICL1 | PAT1 | P41555 | Q6L8K7 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acetyl-CoA acetyltransferase; Essential for n-decane utilization. | 0.638 |
ICL1 | PAY32 | P41555 | Q99144 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | 0.614 |
ICL1 | PEX6 | P41555 | P36966 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Peroxisomal biogenesis factor 6; Involved in peroxisome biosynthesis; Belongs to the AAA ATPase family. | 0.698 |
ICL1 | POX1 | P41555 | O74934 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase 1. | 0.800 |
ICL1 | POX2 | P41555 | O74935 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase 2; Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group. | 0.693 |
ICL1 | POX3 | P41555 | O74936 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase 3; Oxidizes aliphatic acyl-CoA substrates of different chain lengths such as hexanoyl-CoA, decanoyl-CoA and myristoyl-CoA as well as aromatic/heterocyclic ring-substituted chromogenic substrates, such as furylpropionyl-CoA. Of the above substrates, the efficiency of the enzyme, exhibits the following order: decanoyl-CoA > myristoyl-CoA > hexanoyl-CoA > furyl-propionyl-CoA. | 0.470 |
ICL1 | SEC14 | P41555 | P45816 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | SEC14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. | 0.417 |
ICL1 | YALI0_C23859g | P41555 | F2Z630 | Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.518 |