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YALI0_E27654g YALI0_E27654g SEC62 SEC62 PAT1 PAT1 YALI0_E06567g YALI0_E06567g GET1 GET1 CCS1 CCS1 ACEB_YARLI ACEB_YARLI ICL1 ICL1 PEX6 PEX6 POX3 POX3 POX1 POX1 POX2 POX2 YALI0_C23859g YALI0_C23859g
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YALI0_E27654gAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (701 aa)
SEC62Translocation protein SEC62; Required for preprotein translocation. (396 aa)
PAT1Acetyl-CoA acetyltransferase; Essential for n-decane utilization. (397 aa)
YALI0_E06567gAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (689 aa)
GET1Golgi to ER traffic protein 1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP- dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. (224 aa)
CCS1Superoxide dismutase 1 copper chaperone; Copper chaperone for superoxide dismutase 1 (SOD1). Binds copper ions and delivers them specifically to SOD1 (By similarity). (234 aa)
ACEB_YARLI2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. (565 aa)
ICL1Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. (540 aa)
PEX6Peroxisomal biogenesis factor 6; Involved in peroxisome biosynthesis; Belongs to the AAA ATPase family. (1024 aa)
POX3Acyl-coenzyme A oxidase 3; Oxidizes aliphatic acyl-CoA substrates of different chain lengths such as hexanoyl-CoA, decanoyl-CoA and myristoyl-CoA as well as aromatic/heterocyclic ring-substituted chromogenic substrates, such as furylpropionyl-CoA. Of the above substrates, the efficiency of the enzyme, exhibits the following order: decanoyl-CoA > myristoyl-CoA > hexanoyl-CoA > furyl-propionyl-CoA. (700 aa)
POX1Acyl-coenzyme A oxidase 1. (689 aa)
POX2Acyl-coenzyme A oxidase 2; Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group. (700 aa)
YALI0_C23859gAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (699 aa)
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 284591
Other names: Y. lipolytica CLIB122, Yarrowia lipolytica CLIB122
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