19 items (Yarrowia lipolytica) - STRING interaction network

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Your Input:
	YALI0_B10406g	YALI0B10406p; Belongs to the enoyl-CoA hydratase/isomerase family. (346 aa)
	POX2	Acyl-coenzyme A oxidase 2; Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group. (700 aa)
	XPR2	Alkaline extracellular protease; Major secreted protein that belongs to the subtilisin family serine proteases. (454 aa)
	LEU2	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa)
	FAS1	3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl- [acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier- protein] dehydratase. (2086 aa)
	POT1	3-ketoacyl-CoA thiolase, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family. (414 aa)
	URA3	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (286 aa)
	YALI0_F26587g	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (512 aa)
	YALI0_F23749g	YALI0F23749p. (417 aa)
	YALI0_F19184g	YALI0F19184p; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (533 aa)
	YALI0_F10010g	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family. (816 aa)
	YALI0_D17864g	YALI0D17864p. (691 aa)
	YALI0_D17556g	Alkyl transferase; Belongs to the UPP synthase family. (337 aa)
	YALI0_C11407g	YALI0C11407p. (2266 aa)
	KU70	ATP-dependent DNA helicase II subunit 1; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. I [...] (585 aa)
	YALI0_B22550g	YALI0B22550p. (318 aa)
	YALI0_B19382g	3-oxoacyl-[acyl-carrier-protein] reductase. (1850 aa)
	YALI0_B08536g	YALI0B08536p; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
	PAT1	Acetyl-CoA acetyltransferase; Essential for n-decane utilization. (397 aa)

Your Current Organism:

Yarrowia lipolytica

NCBI taxonomy Id: 284591
Other names: Y. lipolytica CLIB122, Yarrowia lipolytica CLIB122

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAS1	POX2	P34229	O74935	3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl- [acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier- protein] dehydratase.	Acyl-coenzyme A oxidase 2; Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group.	0.485
FAS1	YALI0_B08536g	P34229	Q6CFB6	3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl- [acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier- protein] dehydratase.	YALI0B08536p; Belongs to the thiolase-like superfamily. Thiolase family.	0.443
FAS1	YALI0_B19382g	P34229	Q6CE16	3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl- [acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier- protein] dehydratase.	3-oxoacyl-[acyl-carrier-protein] reductase.	0.999
FAS1	YALI0_C11407g	P34229	Q6CC91	3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl- [acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier- protein] dehydratase.	YALI0C11407p.	0.991
FAS1	YALI0_D17864g	P34229	Q6C8Q3	3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl- [acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier- protein] dehydratase.	YALI0D17864p.	0.942
KU70	URA3	Q6CCK2	Q12724	ATP-dependent DNA helicase II subunit 1; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. I [...]	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.	0.907
KU70	XPR2	Q6CCK2	P09230	ATP-dependent DNA helicase II subunit 1; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. I [...]	Alkaline extracellular protease; Major secreted protein that belongs to the subtilisin family serine proteases.	0.636
LEU2	URA3	P18120	Q12724	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.	0.933
LEU2	XPR2	P18120	P09230	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Alkaline extracellular protease; Major secreted protein that belongs to the subtilisin family serine proteases.	0.814
LEU2	YALI0_B22550g	P18120	Q6CDN6	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	YALI0B22550p.	0.612
PAT1	POT1	Q6L8K7	Q05493	Acetyl-CoA acetyltransferase; Essential for n-decane utilization.	3-ketoacyl-CoA thiolase, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.	0.924
PAT1	POX2	Q6L8K7	O74935	Acetyl-CoA acetyltransferase; Essential for n-decane utilization.	Acyl-coenzyme A oxidase 2; Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group.	0.989
PAT1	URA3	Q6L8K7	Q12724	Acetyl-CoA acetyltransferase; Essential for n-decane utilization.	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.	0.670
PAT1	YALI0_B08536g	Q6L8K7	Q6CFB6	Acetyl-CoA acetyltransferase; Essential for n-decane utilization.	YALI0B08536p; Belongs to the thiolase-like superfamily. Thiolase family.	0.903
PAT1	YALI0_B10406g	Q6L8K7	Q6CF43	Acetyl-CoA acetyltransferase; Essential for n-decane utilization.	YALI0B10406p; Belongs to the enoyl-CoA hydratase/isomerase family.	0.886
PAT1	YALI0_B22550g	Q6L8K7	Q6CDN6	Acetyl-CoA acetyltransferase; Essential for n-decane utilization.	YALI0B22550p.	0.948
PAT1	YALI0_C11407g	Q6L8K7	Q6CC91	Acetyl-CoA acetyltransferase; Essential for n-decane utilization.	YALI0C11407p.	0.969
PAT1	YALI0_F23749g	Q6L8K7	Q6C0L1	Acetyl-CoA acetyltransferase; Essential for n-decane utilization.	YALI0F23749p.	0.610
PAT1	YALI0_F26587g	Q6L8K7	Q6C098	Acetyl-CoA acetyltransferase; Essential for n-decane utilization.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.975
POT1	PAT1	Q05493	Q6L8K7	3-ketoacyl-CoA thiolase, peroxisomal; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Essential for n-decane utilization.	0.924