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KAR2 KAR2 YALI0_E06567g YALI0_E06567g YALI0_D21890g YALI0_D21890g YALI0_C17941g YALI0_C17941g YALI0_B22066g YALI0_B22066g PAT1 PAT1 PAY32 PAY32 SIL1 SIL1 URA3 URA3 SEC14 SEC14 ICL1 ICL1 POX3 POX3 POX2 POX2 POX1 POX1 YALI0_C23859g YALI0_C23859g YALI0_E27654g YALI0_E27654g YALI0_E33407g YALI0_E33407g ACEB_YARLI ACEB_YARLI
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
KAR2Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis; Belongs to the heat shock protein 70 family. (670 aa)
YALI0_E06567gAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (689 aa)
YALI0_D21890gYALI0D21890p. (1079 aa)
YALI0_C17941gYALI0C17941p; Belongs to the GDA1/CD39 NTPase family. (539 aa)
YALI0_B22066gPlasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (916 aa)
PAT1Acetyl-CoA acetyltransferase; Essential for n-decane utilization. (397 aa)
PAY32Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. (598 aa)
SIL1Nucleotide exchange factor SIL1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Probably functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2. It is not required for viability but is essential for optimal growth at elevated temperatures. Belongs to the SIL1 family. (426 aa)
URA3Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (286 aa)
SEC14SEC14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. (492 aa)
ICL1Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. (540 aa)
POX3Acyl-coenzyme A oxidase 3; Oxidizes aliphatic acyl-CoA substrates of different chain lengths such as hexanoyl-CoA, decanoyl-CoA and myristoyl-CoA as well as aromatic/heterocyclic ring-substituted chromogenic substrates, such as furylpropionyl-CoA. Of the above substrates, the efficiency of the enzyme, exhibits the following order: decanoyl-CoA > myristoyl-CoA > hexanoyl-CoA > furyl-propionyl-CoA. (700 aa)
POX2Acyl-coenzyme A oxidase 2; Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group. (700 aa)
POX1Acyl-coenzyme A oxidase 1. (689 aa)
YALI0_C23859gAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (699 aa)
YALI0_E27654gAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (701 aa)
YALI0_E33407gYALI0E33407p; Belongs to the GDA1/CD39 NTPase family. (402 aa)
ACEB_YARLI2-methylisocitrate lyase, mitochondrial; Component of the methylcitrate cycle that catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl-CoA; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. (565 aa)
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 284591
Other names: Y. lipolytica CLIB122, Yarrowia lipolytica CLIB122
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