(15 nodes) Nicotinate and nicotinamide metabolism network (Candida glabrata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q6FJK1_CANGA	Nudix hydrolase domain-containing protein. (370 aa)
	HST2	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (364 aa)
	ISN1	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family. (447 aa)
	Q6FLD7_CANGA	Uncharacterized protein. (243 aa)
	Q6FLK1_CANGA	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (431 aa)
	Q6FLR6_CANGA	Uncharacterized protein. (526 aa)
	Q6FNL5_CANGA	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (713 aa)
	Q6FR29_CANGA	Uncharacterized protein. (510 aa)
	SDT1	Uncharacterized protein. (279 aa)
	Q6FRI7_CANGA	Deacetylase sirtuin-type domain-containing protein. (434 aa)
	Q6FU79_CANGA	Deacetylase sirtuin-type domain-containing protein. (364 aa)
	SIR2-2	NAD-dependent histone deacetylase SIR2; NAD-dependent deacetylase. Heterochromatin component that silences transcription at silent mating loci, telomeres and the ribosomal DNA, and that also suppresses recombination in the rDNA and extends replicative life span. It acts as a NAD-dependent histone deacetylase, which deacetylates 'Lys-9' and 'Lys-14' of Histone H3 and 'Lys-16' of Histone H4 (By similarity); Belongs to the sirtuin family. Class I subfamily. (509 aa)
	PHM8	Uncharacterized protein. (314 aa)
	Q6FX56_CANGA	CTP_transf_like domain-containing protein. (275 aa)
	Q6FXW7_CANGA	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (411 aa)

Your Current Organism:

Candida glabrata

NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HST2	Q6FJK1_CANGA	Q6FKU1	Q6FJK1	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	Nudix hydrolase domain-containing protein.	0.908
HST2	Q6FLR6_CANGA	Q6FKU1	Q6FLR6	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	Uncharacterized protein.	0.909
HST2	Q6FNL5_CANGA	Q6FKU1	Q6FNL5	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.932
HST2	Q6FR29_CANGA	Q6FKU1	Q6FR29	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	Uncharacterized protein.	0.909
HST2	Q6FRI7_CANGA	Q6FKU1	Q6FRI7	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	Deacetylase sirtuin-type domain-containing protein.	0.506
HST2	Q6FU79_CANGA	Q6FKU1	Q6FU79	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	Deacetylase sirtuin-type domain-containing protein.	0.512
HST2	Q6FX56_CANGA	Q6FKU1	Q6FX56	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	CTP_transf_like domain-containing protein.	0.900
HST2	Q6FXW7_CANGA	Q6FKU1	Q6FXW7	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.	0.922
HST2	SIR2-2	Q6FKU1	Q6FWI7	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.	NAD-dependent histone deacetylase SIR2; NAD-dependent deacetylase. Heterochromatin component that silences transcription at silent mating loci, telomeres and the ribosomal DNA, and that also suppresses recombination in the rDNA and extends replicative life span. It acts as a NAD-dependent histone deacetylase, which deacetylates 'Lys-9' and 'Lys-14' of Histone H3 and 'Lys-16' of Histone H4 (By similarity); Belongs to the sirtuin family. Class I subfamily.	0.538
ISN1	PHM8	Q6FLD4	Q6FWW7	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.	Uncharacterized protein.	0.905
ISN1	Q6FJK1_CANGA	Q6FLD4	Q6FJK1	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.	Nudix hydrolase domain-containing protein.	0.903
ISN1	Q6FLD7_CANGA	Q6FLD4	Q6FLD7	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.	Uncharacterized protein.	0.510
ISN1	Q6FLK1_CANGA	Q6FLD4	Q6FLK1	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.	0.905
ISN1	Q6FNL5_CANGA	Q6FLD4	Q6FNL5	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.596
ISN1	Q6FX56_CANGA	Q6FLD4	Q6FX56	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.	CTP_transf_like domain-containing protein.	0.918
ISN1	Q6FXW7_CANGA	Q6FLD4	Q6FXW7	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.	0.918
ISN1	SDT1	Q6FLD4	Q6FRE4	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.	Uncharacterized protein.	0.975
ISN1	SIR2-2	Q6FLD4	Q6FWI7	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.	NAD-dependent histone deacetylase SIR2; NAD-dependent deacetylase. Heterochromatin component that silences transcription at silent mating loci, telomeres and the ribosomal DNA, and that also suppresses recombination in the rDNA and extends replicative life span. It acts as a NAD-dependent histone deacetylase, which deacetylates 'Lys-9' and 'Lys-14' of Histone H3 and 'Lys-16' of Histone H4 (By similarity); Belongs to the sirtuin family. Class I subfamily.	0.443
PHM8	ISN1	Q6FWW7	Q6FLD4	Uncharacterized protein.	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family.	0.905
PHM8	Q6FJK1_CANGA	Q6FWW7	Q6FJK1	Uncharacterized protein.	Nudix hydrolase domain-containing protein.	0.942

page 1 of 7

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About