STRINGSTRING
HAS1 HAS1 Q6FIU8_CANGA Q6FIU8_CANGA Q6FIW9_CANGA Q6FIW9_CANGA Q6FIX0_CANGA Q6FIX0_CANGA MRT4 MRT4 Q6FJJ7_CANGA Q6FJJ7_CANGA Q6FJZ3_CANGA Q6FJZ3_CANGA IPI1 IPI1 Q6FKC5_CANGA Q6FKC5_CANGA YTM1 YTM1 Q6FKM0_CANGA Q6FKM0_CANGA SPB4 SPB4 ALB1 ALB1 Q6FL95_CANGA Q6FL95_CANGA ERB1 ERB1 Q6FLF5_CANGA Q6FLF5_CANGA Q6FLJ8_CANGA Q6FLJ8_CANGA Q6FLV6_CANGA Q6FLV6_CANGA Q6FLX1_CANGA Q6FLX1_CANGA Q6FN01_CANGA Q6FN01_CANGA TIF6 TIF6 NSA2 NSA2 DBP10 DBP10 IPI3 IPI3 Q6FNK1_CANGA Q6FNK1_CANGA Q6FNK9_CANGA Q6FNK9_CANGA Q6FNP8_CANGA Q6FNP8_CANGA Q6FPC4_CANGA Q6FPC4_CANGA Q6FPI9_CANGA Q6FPI9_CANGA RLP24 RLP24 Q6FPW2_CANGA Q6FPW2_CANGA Q6FQ98_CANGA Q6FQ98_CANGA Q6FQW6_CANGA Q6FQW6_CANGA Q6FRC3_CANGA Q6FRC3_CANGA NOG1 NOG1 RLP7 RLP7 Q6FSA9_CANGA Q6FSA9_CANGA NOP7 NOP7 Q6FSV5_CANGA Q6FSV5_CANGA Q6FT11_CANGA Q6FT11_CANGA SDA1 SDA1 NSA1 NSA1 DBP9 DBP9 Q6FUE5_CANGA Q6FUE5_CANGA LOC1 LOC1 NOP12 NOP12 Q6FUT9_CANGA Q6FUT9_CANGA NOP9 NOP9 CGR1 CGR1 Q6FVW5_CANGA Q6FVW5_CANGA DRS1 DRS1 Q6FW55_CANGA Q6FW55_CANGA RIX1 RIX1 Q6FWE4_CANGA Q6FWE4_CANGA NOG2 NOG2 SPB1 SPB1 MRD1 MRD1 MAK5 MAK5 Q6FY93_CANGA Q6FY93_CANGA NOP16 NOP16 DBP7 DBP7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HAS1ATP-dependent RNA helicase HAS1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA. (494 aa)
Q6FIU8_CANGAMidasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4880 aa)
Q6FIW9_CANGACBF domain-containing protein. (990 aa)
Q6FIX0_CANGAUncharacterized protein. (270 aa)
MRT4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
Q6FJJ7_CANGA60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (181 aa)
Q6FJZ3_CANGARibosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (447 aa)
IPI1Pre-rRNA-processing protein IPI1; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA. (334 aa)
Q6FKC5_CANGAUncharacterized protein. (682 aa)
YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (457 aa)
Q6FKM0_CANGABrix domain-containing protein. (349 aa)
SPB4ATP-dependent rRNA helicase SPB4; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2. (617 aa)
ALB1Ribosome biogenesis protein ALB1; Involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm (By similarity). (162 aa)
Q6FL95_CANGAUncharacterized protein. (453 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (805 aa)
Q6FLF5_CANGARRM domain-containing protein. (255 aa)
Q6FLJ8_CANGAUncharacterized protein. (712 aa)
Q6FLV6_CANGAUncharacterized protein. (387 aa)
Q6FLX1_CANGAC2H2-type domain-containing protein. (172 aa)
Q6FN01_CANGAWD_REPEATS_REGION domain-containing protein. (513 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (245 aa)
NSA2Ribosome biogenesis protein NSA2; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity). (261 aa)
DBP10ATP-dependent RNA helicase DBP10; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (969 aa)
IPI3Pre-rRNA-processing protein IPI3; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA. (528 aa)
Q6FNK1_CANGANucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (671 aa)
Q6FNK9_CANGABrix domain-containing protein. (464 aa)
Q6FNP8_CANGASAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (619 aa)
Q6FPC4_CANGAUncharacterized protein. (1065 aa)
Q6FPI9_CANGAWD_REPEATS_REGION domain-containing protein. (517 aa)
RLP24Ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of NOG1 to pre-60S particles. Activates and recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles. (197 aa)
Q6FPW2_CANGAUncharacterized protein. (365 aa)
Q6FQ98_CANGABrix domain-containing protein. (294 aa)
Q6FQW6_CANGAPUM-HD domain-containing protein. (667 aa)
Q6FRC3_CANGACP-type G domain-containing protein. (519 aa)
NOG1Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (645 aa)
RLP7Ribosome biogenesis protein RLP7; Involved in the biogenesis of the 60S ribosomal subunit. May act as a specificity factor that binds precursor rRNAs and tethers the enzymes that carry out the early 5' to 3' exonucleolytic reactions that generate the mature rRNAs (By similarity); Belongs to the universal ribosomal protein uL30 family. (317 aa)
Q6FSA9_CANGABrix domain-containing protein. (294 aa)
NOP7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (598 aa)
Q6FSV5_CANGARibosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (203 aa)
Q6FT11_CANGAProtein MAK16; Belongs to the MAK16 family. (297 aa)
SDA1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (745 aa)
NSA1Ribosome biogenesis protein NSA1; Involved in the biogenesis of the 60S ribosomal subunit. (436 aa)
DBP9ATP-dependent RNA helicase DBP9; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily. (595 aa)
Q6FUE5_CANGAUncharacterized protein. (111 aa)
LOC160S ribosomal subunit assembly/export protein LOC1; Required for efficient assembly and nuclear export of the 60S ribosomal subunit. (203 aa)
NOP12Nucleolar protein 12; Involved in pre-25S rRNA processing; Belongs to the RRM RBM34 family. (396 aa)
Q6FUT9_CANGAProtein MAK16; Belongs to the MAK16 family. (310 aa)
NOP9Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family. (665 aa)
CGR1rRNA-processing protein CGR1; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit; Belongs to the CGR1 family. (114 aa)
Q6FVW5_CANGAUncharacterized protein. (228 aa)
DRS1ATP-dependent RNA helicase DRS1; ATP-binding RNA helicase involved in ribosome assembly. (725 aa)
Q6FW55_CANGAUncharacterized protein. (834 aa)
RIX1Pre-rRNA-processing protein RIX1; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre- 60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1. (767 aa)
Q6FWE4_CANGAUncharacterized protein. (619 aa)
NOG2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (494 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (837 aa)
MRD1Multiple RNA-binding domain-containing protein 1; Involved in pre-rRNA processing; Belongs to the RRM MRD1 family. (861 aa)
MAK5ATP-dependent RNA helicase MAK5; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs; Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily. (733 aa)
Q6FY93_CANGAWD_REPEATS_REGION domain-containing protein. (583 aa)
NOP16Nucleolar protein 16; Involved in the biogenesis of the 60S ribosomal subunit. (238 aa)
DBP7ATP-dependent RNA helicase DBP7; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs. (715 aa)
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
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