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OCT1 | Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity). (761 aa) | ||||
Q6FW95_CANGA | Uncharacterized protein. (181 aa) | ||||
MDM10 | Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (460 aa) | ||||
Q6FWZ1_CANGA | Uncharacterized protein. (111 aa) | ||||
Q6FYA4_CANGA | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (181 aa) | ||||
TIM50 | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity). (485 aa) | ||||
MAS1 | Uncharacterized protein; Belongs to the peptidase M16 family. (465 aa) | ||||
MIC60 | MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity). (520 aa) | ||||
MMM1 | Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (431 aa) | ||||
MIA40 | Mitochondrial intermembrane space import and assembly protein 40; Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond [...] (404 aa) | ||||
Q6FW68_CANGA | J domain-containing protein. (143 aa) | ||||
Q6FRU6_CANGA | Uncharacterized protein. (113 aa) | ||||
B4UMZ0_CANGA | Uncharacterized protein. (49 aa) | ||||
B4UMZ9_CANGA | zf-Tim10_DDP domain-containing protein. (93 aa) | ||||
B4UN53_CANGA | Uncharacterized protein. (61 aa) | ||||
Q6FJE9_CANGA | Bac_surface_Ag domain-containing protein. (466 aa) | ||||
PAM17 | Presequence translocated-associated motor subunit PAM17, mitochondrial; Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. (186 aa) | ||||
TIM8 | Mitochondrial import inner membrane translocase subunit TIM8; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (87 aa) | ||||
Q6FKB3_CANGA | Uncharacterized protein. (600 aa) | ||||
Q6FKE2_CANGA | Uncharacterized protein. (452 aa) | ||||
Q6FLE4_CANGA | Uncharacterized protein. (587 aa) | ||||
Q6FMA7_CANGA | Uncharacterized protein. (145 aa) | ||||
MCX1 | Uncharacterized protein. (549 aa) | ||||
HSP60 | Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (568 aa) | ||||
Q6FMU6_CANGA | AAA domain-containing protein. (745 aa) | ||||
TIM21 | Mitochondrial import inner membrane translocase subunit TIM21; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity). (215 aa) | ||||
Q6FMZ6_CANGA | AAA domain-containing protein; Belongs to the AAA ATPase family. (359 aa) | ||||
Q6FNC3_CANGA | Uncharacterized protein. (184 aa) | ||||
Q6FNP1_CANGA | Uncharacterized protein. (60 aa) | ||||
YDJ1 | Uncharacterized protein. (407 aa) | ||||
TIM22 | Mitochondrial import inner membrane translocase subunit TIM22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (193 aa) | ||||
PAM16 | Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. (146 aa) | ||||
Q6FTP2_CANGA | Sulfhydryl oxidase. (174 aa) | ||||
Q6FU46_CANGA | Uncharacterized protein. (300 aa) | ||||
Q6FU64_CANGA | Peptidase_S24 domain-containing protein. (171 aa) | ||||
Q6FUR7_CANGA | Uncharacterized protein. (125 aa) | ||||
TIM54 | Mitochondrial import inner membrane translocase subunit TIM54; Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as external driving force (By similarity). (452 aa) | ||||
mge1 | GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity). (231 aa) | ||||
Q6FPN3_CANGA | Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (412 aa) | ||||
Q6FPQ5_CANGA | J domain-containing protein. (425 aa) | ||||
PAM18 | Mitochondrial import inner membrane translocase subunit TIM14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity); Belongs to the TIM14 family. (153 aa) | ||||
Q6FPV3_CANGA | Uncharacterized protein; Belongs to the peptidase M16 family. (481 aa) | ||||
Q6FQG0_CANGA | Uncharacterized protein. (386 aa) | ||||
Q6FQI7_CANGA | Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (161 aa) | ||||
MDM12 | Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (257 aa) | ||||
Q6FQJ6_CANGA | Uncharacterized protein. (382 aa) | ||||
Q6FQK3_CANGA | Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (212 aa) | ||||
Q6FR61_CANGA | Mitochondrial inner membrane protease subunit. (189 aa) | ||||
Q6FRD6_CANGA | AAA domain-containing protein. (750 aa) | ||||
TIM13 | Mitochondrial import inner membrane translocase subunit TIM13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (95 aa) | ||||
Q6FRH4_CANGA | zf-Tim10_DDP domain-containing protein. (101 aa) | ||||
HSP10 | Uncharacterized protein; Belongs to the GroES chaperonin family. (106 aa) | ||||
Q6FRI9_CANGA | Uncharacterized protein. (583 aa) | ||||
TIM9 | Mitochondrial import inner membrane translocase subunit TIM9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (87 aa) |