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RAT1 | 5'-3' exoribonuclease 2; Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II (By similarity); Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily. (1018 aa) | ||||
Q6FVM3_CANGA | Kinase; Belongs to the inositol phosphokinase (IPK) family. (349 aa) | ||||
SRB8 | Mediator of RNA polymerase II transcription subunit 12; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity). (1358 aa) | ||||
Q6FVN2_CANGA | WD_REPEATS_REGION domain-containing protein. (836 aa) | ||||
Q6FVQ2_CANGA | Protein kinase domain-containing protein. (725 aa) | ||||
SRB2 | Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (215 aa) | ||||
MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (565 aa) | ||||
Q6FWC0_CANGA | TPR_REGION domain-containing protein. (1148 aa) | ||||
Q6FWF5_CANGA | Uncharacterized protein. (338 aa) | ||||
Q6FWG1_CANGA | GATA-type domain-containing protein. (712 aa) | ||||
Q6FWL6_CANGA | Uncharacterized protein. (194 aa) | ||||
MED2 | Mediator of RNA polymerase II transcription subunit 2; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (368 aa) | ||||
HTA1 | Histone H2A.1; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (131 aa) | ||||
Q6FN90_CANGA | Protein kinase domain-containing protein. (504 aa) | ||||
EAF3 | Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (355 aa) | ||||
STE20 | Serine/threonine-protein kinase STE20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity). Involved in cell wall integrity, hypertonic stress adaptation and virulence. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (915 aa) | ||||
OPI1 | Uncharacterized protein. (487 aa) | ||||
SPT4 | Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (102 aa) | ||||
Q6FMS3_CANGA | Uncharacterized protein. (430 aa) | ||||
ERT1 | Transcription activator of gluconeogenesis ERT1; Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity). Belongs to the ERT1/acuK family. (596 aa) | ||||
Q6FMB7_CANGA | Uncharacterized protein. (396 aa) | ||||
Q6FM26_CANGA | Protein kinase domain-containing protein. (538 aa) | ||||
Q6FLZ9_CANGA | Uncharacterized protein. (535 aa) | ||||
Q6FLY5_CANGA | Protein kinase domain-containing protein. (360 aa) | ||||
Q6FLR4_CANGA | Uncharacterized protein. (392 aa) | ||||
RGT1 | Glucose transport transcription regulator RGT1; Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose. In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator. In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription (By similarity); Belongs to the EDS1/RGT1 family. (1287 aa) | ||||
Q6FLN7_CANGA | Uncharacterized protein. (503 aa) | ||||
GCN4 | BZIP domain-containing protein. (310 aa) | ||||
SPT6 | Transcription elongation factor SPT6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity); Belongs to the SPT6 family. (1449 aa) | ||||
Q6FL75_CANGA | N-acetyltransferase domain-containing protein. (531 aa) | ||||
Q6FKS6_CANGA | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (233 aa) | ||||
MED7 | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (230 aa) | ||||
RFM1 | Uncharacterized protein. (308 aa) | ||||
Q6FKH2_CANGA | Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (507 aa) | ||||
Q6FKG8_CANGA | Uncharacterized protein. (336 aa) | ||||
Q6FKG7_CANGA | Uncharacterized protein. (825 aa) | ||||
Q6FKG0_CANGA | Uncharacterized protein. (980 aa) | ||||
PHO85 | Negative regulator of the PHO system; When phosphate concentrations are high it phosphorylates the PHO4 transcription factor thus establishing repression; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. (302 aa) | ||||
Q6FKD0_CANGA | Uncharacterized protein. (223 aa) | ||||
SSN3 | Serine/threonine-protein kinase SSN3; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity). (567 aa) | ||||
SET1 | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. Belongs to the class V-like SAM-binding methyltransferase superfamily. (1111 aa) | ||||
RGR1 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (1037 aa) | ||||
HIR3 | Histone transcription regulator 3 homolog; Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation. Belongs to the HIR3 family. (1615 aa) | ||||
Q6FK35_CANGA | CBFD_NFYB_HMF domain-containing protein. (144 aa) | ||||
Q6FJY6_CANGA | Uncharacterized protein. (457 aa) | ||||
Q6FNH7_CANGA | HDAC_interact domain-containing protein. (937 aa) | ||||
SSN2 | Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity). (1345 aa) | ||||
Q6FNN6_CANGA | DUF1752 domain-containing protein. (659 aa) | ||||
Q6FNP4_CANGA | Uncharacterized protein. (810 aa) | ||||
SIN4 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (973 aa) | ||||
SKO1 | BZIP domain-containing protein. (513 aa) | ||||
Q6FPE3_CANGA | GLUE N-terminal domain-containing protein. (521 aa) | ||||
Q6FPG7_CANGA | WD_REPEATS_REGION domain-containing protein. (435 aa) | ||||
Q6FJY2_CANGA | Zn(2)-C6 fungal-type domain-containing protein. (462 aa) | ||||
Q6FJT6_CANGA | Non-specific serine/threonine protein kinase. (861 aa) | ||||
ACE2 | Cell wall transcription factor ACE2; Transcription factor involved in the RAM (regulation of ACE2 transcription factor and polarized morphogenesis) signaling network that regulates polarized morphogenesis. Regulates expression of genes involved in cell separation or other cell wall genes. Required for regulation of morphogenesis, cell separation, adherence, biofilm formation, invasion, as well as virulence. (703 aa) | ||||
MED8 | Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (233 aa) | ||||
OAF3 | Oleate activated transcription factor 3; Transcriptional inhibitor with a significantly increased number of target genes in response to oleate; Belongs to the OAF3 family. (891 aa) | ||||
Q6FJF5_CANGA | Uncharacterized protein. (362 aa) | ||||
SSN8 | RNA polymerase II holoenzyme cyclin-like subunit; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By s [...] (339 aa) | ||||
Q6FJB7_CANGA | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (165 aa) | ||||
ROX3 | Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (201 aa) | ||||
MAF1 | Repressor of RNA polymerase III transcription MAF1; Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA (By similarity); Belongs to the MAF1 family. (391 aa) | ||||
RAP1 | Uncharacterized protein. (687 aa) | ||||
Q6FPH4_CANGA | WD_REPEATS_REGION domain-containing protein. (420 aa) | ||||
HDA1 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (693 aa) | ||||
Q6FPR6_CANGA | PHD-type domain-containing protein. (671 aa) | ||||
Q6FPT2_CANGA | Uncharacterized protein. (479 aa) | ||||
Q6FQ29_CANGA | Uncharacterized protein. (1039 aa) | ||||
Q6FQ34_CANGA | Protein kinase domain-containing protein. (528 aa) | ||||
Q6FQ70_CANGA | CBFD_NFYB_HMF domain-containing protein. (139 aa) | ||||
NUT2 | Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (199 aa) | ||||
Q6FQE1_CANGA | Uncharacterized protein; Belongs to the BolA/IbaG family. (84 aa) | ||||
GLN3 | GATA-type domain-containing protein. (823 aa) | ||||
Q6FX02_CANGA | Homeobox domain-containing protein. (221 aa) | ||||
SET2 | Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (716 aa) | ||||
Q6FX68_CANGA | Uncharacterized protein. (121 aa) | ||||
RPD3 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (433 aa) | ||||
Q6FXJ5_CANGA | Zn(2)-C6 fungal-type domain-containing protein. (1355 aa) | ||||
Q6FXJ9_CANGA | Uncharacterized protein. (438 aa) | ||||
Q6FXP9_CANGA | Peptidyl-prolyl cis-trans isomerase. (173 aa) | ||||
MIG1 | Uncharacterized protein. (424 aa) | ||||
URE2 | Protein URE2; Plays an important role in the cellular response to the nitrogen source. URE2 gene plays a major part in the repression of GLN1 and GDH2 genes by glutamine, and is required for the inactivation of glutamine synthetase. URE2 gene product may catalytically inactivate GLN3 in response to an increase in the intracellular concentration of glutamine (By similarity); Belongs to the GST superfamily. (355 aa) | ||||
Q6FQF4_CANGA | Uncharacterized protein. (233 aa) | ||||
NRM1 | Transcription factor NRM1; Negative regulatory component of the MBF complex involved in cell-cycle-dependent transcription. (293 aa) | ||||
CSE2 | Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (152 aa) | ||||
Q6FQL0_CANGA | Uncharacterized protein. (1026 aa) | ||||
HMT1 | Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (348 aa) | ||||
STB5 | Negative regulator of pleiotropic drug resistance STB5; Transcription factor that negatively regulates pleiotropic drug resistance genes, including the ABC transporter genes CDR1, PDH1, and YOR1. (1005 aa) | ||||
HIR2 | Protein HIR2; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (997 aa) | ||||
Q6FRF3_CANGA | Uncharacterized protein. (1258 aa) | ||||
Q6FRH6_CANGA | RXT2_N domain-containing protein. (421 aa) | ||||
RTT106 | Histone chaperone RTT106; Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity). (453 aa) | ||||
RTF1 | Plus3 domain-containing protein. (566 aa) | ||||
Q6FRL9_CANGA | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa) | ||||
GAL11 | Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (1095 aa) | ||||
Q6FRT0_CANGA | Uncharacterized protein. (1126 aa) | ||||
Q6FRV8_CANGA | Uncharacterized protein. (1904 aa) | ||||
Q6FRW4_CANGA | GCR1_C domain-containing protein. (1017 aa) | ||||
Q6FRZ2_CANGA | Uncharacterized protein. (383 aa) | ||||
SPT5 | Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (1010 aa) | ||||
AFT1 | Uncharacterized protein. (535 aa) | ||||
Q6FS97_CANGA | SAP30_Sin3_bdg domain-containing protein. (178 aa) | ||||
Q6FSD8_CANGA | Uncharacterized protein. (714 aa) | ||||
Q6FSH3_CANGA | Uncharacterized protein. (740 aa) | ||||
Q6FSH9_CANGA | Zn(2)-C6 fungal-type domain-containing protein. (940 aa) | ||||
Q6FSK5_CANGA | Uncharacterized protein. (644 aa) | ||||
Q6FSP6_CANGA | Uncharacterized protein. (609 aa) | ||||
Q6FSW8_CANGA | Homeobox domain-containing protein. (345 aa) | ||||
PHO23 | Chromatin modification-related protein. (316 aa) | ||||
Q6FT50_CANGA | Uncharacterized protein. (550 aa) | ||||
Q6FT94_CANGA | GATA-type domain-containing protein. (462 aa) | ||||
Q6FTA9_CANGA | Uncharacterized protein; Belongs to the peptidase M24B family. (755 aa) | ||||
Q6FTI6_CANGA | Uncharacterized protein. (1154 aa) | ||||
Q6FTK6_CANGA | Uncharacterized protein. (1359 aa) | ||||
Q6FTQ6_CANGA | Bromo domain-containing protein. (1317 aa) | ||||
Q6FU54_CANGA | MADS-box domain-containing protein. (218 aa) | ||||
Q6FU79_CANGA | Deacetylase sirtuin-type domain-containing protein. (364 aa) | ||||
SPT8 | WD_REPEATS_REGION domain-containing protein. (600 aa) | ||||
Q6FUU6_CANGA | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (128 aa) | ||||
HIR1 | Protein HIR1; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (840 aa) | ||||
PHO80 | Uncharacterized protein. (342 aa) | ||||
Q6FVE5_CANGA | Uncharacterized protein. (315 aa) | ||||
SIN3 | HDAC_interact domain-containing protein. (1493 aa) |