STRINGSTRING
B4UMZ9_CANGA B4UMZ9_CANGA Q6FY46_CANGA Q6FY46_CANGA Q6FXK3_CANGA Q6FXK3_CANGA Q6FW57_CANGA Q6FW57_CANGA Q6FVL0_CANGA Q6FVL0_CANGA TIM22 TIM22 Q6FSV8_CANGA Q6FSV8_CANGA SEC61 SEC61 TIM50 TIM50 SEC62 SEC62 TIM9 TIM9 TIM13 TIM13 Q6FQK3_CANGA Q6FQK3_CANGA Q6FQJ6_CANGA Q6FQJ6_CANGA Q6FQI7_CANGA Q6FQI7_CANGA Q6FPC1_CANGA Q6FPC1_CANGA TIM54 TIM54 Q6FNP1_CANGA Q6FNP1_CANGA Q6FJE9_CANGA Q6FJE9_CANGA Q6FJI1_CANGA Q6FJI1_CANGA TIM8 TIM8 Q6FKB3_CANGA Q6FKB3_CANGA Q6FLE4_CANGA Q6FLE4_CANGA Q6FMA7_CANGA Q6FMA7_CANGA B4UN64_CANGA B4UN64_CANGA B4UN15_CANGA B4UN15_CANGA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B4UMZ9_CANGAzf-Tim10_DDP domain-containing protein. (93 aa)
Q6FY46_CANGAUncharacterized protein; Belongs to the AAA ATPase family. (457 aa)
Q6FXK3_CANGAPlug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family. (491 aa)
Q6FW57_CANGAWSC domain-containing protein. (463 aa)
Q6FVL0_CANGAUncharacterized protein. (378 aa)
TIM22Mitochondrial import inner membrane translocase subunit TIM22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (193 aa)
Q6FSV8_CANGAJ domain-containing protein. (668 aa)
SEC61Protein transport protein SEC61 subunit alpha; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins and is essential for cell growth. It interacts with other membrane proteins required for protein translocation. Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event. A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity). (479 aa)
TIM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity). (485 aa)
SEC62Translocation protein SEC62; Required for preprotein translocation. (257 aa)
TIM9Mitochondrial import inner membrane translocase subunit TIM9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (87 aa)
TIM13Mitochondrial import inner membrane translocase subunit TIM13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (95 aa)
Q6FQK3_CANGAMitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (212 aa)
Q6FQJ6_CANGAUncharacterized protein. (382 aa)
Q6FQI7_CANGAMitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (161 aa)
Q6FPC1_CANGAUncharacterized protein. (339 aa)
TIM54Mitochondrial import inner membrane translocase subunit TIM54; Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as external driving force (By similarity). (452 aa)
Q6FNP1_CANGAUncharacterized protein. (60 aa)
Q6FJE9_CANGABac_surface_Ag domain-containing protein. (466 aa)
Q6FJI1_CANGAUncharacterized protein. (230 aa)
TIM8Mitochondrial import inner membrane translocase subunit TIM8; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (87 aa)
Q6FKB3_CANGAUncharacterized protein. (600 aa)
Q6FLE4_CANGAUncharacterized protein. (587 aa)
Q6FMA7_CANGAUncharacterized protein. (145 aa)
B4UN64_CANGAUncharacterized protein. (72 aa)
B4UN15_CANGAProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (85 aa)
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
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