STRINGSTRING
CYT1 CYT1 Q6FY46_CANGA Q6FY46_CANGA COX12 COX12 Q6FY97_CANGA Q6FY97_CANGA Q6FY98_CANGA Q6FY98_CANGA Q6FYA4_CANGA Q6FYA4_CANGA Q6FYB1_CANGA Q6FYB1_CANGA URA9 URA9 COX3 COX3 ATP9 ATP9 ATP6 ATP6 COX1 COX1 COB COB Q6FY44_CANGA Q6FY44_CANGA ATP22 ATP22 Q6FXW3_CANGA Q6FXW3_CANGA Q6FXW2_CANGA Q6FXW2_CANGA Q6FXM7_CANGA Q6FXM7_CANGA Q6FXJ4_CANGA Q6FXJ4_CANGA SYM1 SYM1 Q6FXC0_CANGA Q6FXC0_CANGA MGR1 MGR1 Q6FX67_CANGA Q6FX67_CANGA Q6FWY1_CANGA Q6FWY1_CANGA ATP10 ATP10 Q6FWU2_CANGA Q6FWU2_CANGA SDH2 SDH2 Q6FWR3_CANGA Q6FWR3_CANGA Q6FWQ7_CANGA Q6FWQ7_CANGA ATP16 ATP16 COX9 COX9 Q6FW91_CANGA Q6FW91_CANGA Q6FW87_CANGA Q6FW87_CANGA Q6FW68_CANGA Q6FW68_CANGA COX16 COX16 MIA40 MIA40 RRG8 RRG8 Q6FVX7_CANGA Q6FVX7_CANGA Q6FVW7_CANGA Q6FVW7_CANGA Q6FVP0_CANGA Q6FVP0_CANGA Q6FVF1_CANGA Q6FVF1_CANGA Q6FV90_CANGA Q6FV90_CANGA Q6FV78_CANGA Q6FV78_CANGA MRS2 MRS2 Q6FUW0_CANGA Q6FUW0_CANGA Q6FUR6_CANGA Q6FUR6_CANGA Q6FUQ4_CANGA Q6FUQ4_CANGA Q6FUE0_CANGA Q6FUE0_CANGA Q6FUC4_CANGA Q6FUC4_CANGA Q6FUA3_CANGA Q6FUA3_CANGA COQ4 COQ4 Q6FU83_CANGA Q6FU83_CANGA Q6FU68_CANGA Q6FU68_CANGA Q6FU64_CANGA Q6FU64_CANGA CCS1 CCS1 Q6FU32_CANGA Q6FU32_CANGA Q6FU14_CANGA Q6FU14_CANGA Q6FU13_CANGA Q6FU13_CANGA Q6FTZ1_CANGA Q6FTZ1_CANGA Q6FTY1_CANGA Q6FTY1_CANGA COQ6 COQ6 Q6FTI1_CANGA Q6FTI1_CANGA TPC1 TPC1 Q6FTB4_CANGA Q6FTB4_CANGA PAM16 PAM16 RRG1 RRG1 TIM22 TIM22 MIC27 MIC27 Q6FSY7_CANGA Q6FSY7_CANGA RCF1 RCF1 MIC60 MIC60 Q6FSU3_CANGA Q6FSU3_CANGA QCR2 QCR2 QCR7 QCR7 Q6FSE9_CANGA Q6FSE9_CANGA ATP5 ATP5 Q6FS91_CANGA Q6FS91_CANGA Q6FS56_CANGA Q6FS56_CANGA Q6FS17_CANGA Q6FS17_CANGA TIM50 TIM50 ATP4 ATP4 Q6FRU6_CANGA Q6FRU6_CANGA INA17 INA17 Q6FRU2_CANGA Q6FRU2_CANGA TIM9 TIM9 Q6FRQ5_CANGA Q6FRQ5_CANGA Q6FRH4_CANGA Q6FRH4_CANGA Q6FRE0_CANGA Q6FRE0_CANGA Q6FRD6_CANGA Q6FRD6_CANGA Q6FRD2_CANGA Q6FRD2_CANGA Q6FR99_CANGA Q6FR99_CANGA Q6FR66_CANGA Q6FR66_CANGA Q6FR61_CANGA Q6FR61_CANGA Q6FR47_CANGA Q6FR47_CANGA Q6FQZ1_CANGA Q6FQZ1_CANGA Q6FQY2_CANGA Q6FQY2_CANGA Q6FQS1_CANGA Q6FQS1_CANGA Q6FQP5_CANGA Q6FQP5_CANGA Q6FQN6_CANGA Q6FQN6_CANGA Q6FQK3_CANGA Q6FQK3_CANGA Q6FQI7_CANGA Q6FQI7_CANGA Q6FQH1_CANGA Q6FQH1_CANGA Q6FQG9_CANGA Q6FQG9_CANGA NUC1 NUC1 Q6FQG0_CANGA Q6FQG0_CANGA Q6FQF9_CANGA Q6FQF9_CANGA Q6FQE7_CANGA Q6FQE7_CANGA COQ3 COQ3 AIM5 AIM5 Q6FPZ9_CANGA Q6FPZ9_CANGA COX6 COX6 Q6FPU5_CANGA Q6FPU5_CANGA PAM18 PAM18 ATP25 ATP25 Q6FPT0_CANGA Q6FPT0_CANGA Q6FPS4_CANGA Q6FPS4_CANGA Q6FPN3_CANGA Q6FPN3_CANGA PET117 PET117 Q6FPJ6_CANGA Q6FPJ6_CANGA mge1 mge1 Q6FPG0_CANGA Q6FPG0_CANGA Q6FPF5_CANGA Q6FPF5_CANGA TIM54 TIM54 PSD1 PSD1 Q6FN98_CANGA Q6FN98_CANGA Q6FN64_CANGA Q6FN64_CANGA Q6FN44_CANGA Q6FN44_CANGA Q6FN43_CANGA Q6FN43_CANGA Q6FN13_CANGA Q6FN13_CANGA TIM21 TIM21 Q6FMX2_CANGA Q6FMX2_CANGA PURA_CANGA PURA_CANGA Q6FMU6_CANGA Q6FMU6_CANGA Q6FMN6_CANGA Q6FMN6_CANGA MDM32 MDM32 COQ7 COQ7 Q6FM68_CANGA Q6FM68_CANGA Q6FM52_CANGA Q6FM52_CANGA FMN1 FMN1 Q6FM36_CANGA Q6FM36_CANGA Q6FM23_CANGA Q6FM23_CANGA Q6FLW8_CANGA Q6FLW8_CANGA Q6FLN4_CANGA Q6FLN4_CANGA Q6FLK2_CANGA Q6FLK2_CANGA Q6FLH9_CANGA Q6FLH9_CANGA HEM15 HEM15 Q6FLB5_CANGA Q6FLB5_CANGA Q6FLB3_CANGA Q6FLB3_CANGA SUN4 SUN4 Q6FL51_CANGA Q6FL51_CANGA Q6FL49_CANGA Q6FL49_CANGA Q6FL37_CANGA Q6FL37_CANGA AEP3 AEP3 ATP7 ATP7 Q6FY45_CANGA Q6FY45_CANGA Q6FKA2_CANGA Q6FKA2_CANGA SHE9 SHE9 Q6FJY1_CANGA Q6FJY1_CANGA Q6FJQ3_CANGA Q6FJQ3_CANGA PAM17 PAM17 Q6FJG9_CANGA Q6FJG9_CANGA Q6FJD4_CANGA Q6FJD4_CANGA LPE10 LPE10 Q6FJB8_CANGA Q6FJB8_CANGA Q6FJA1_CANGA Q6FJA1_CANGA Q6FJ35_CANGA Q6FJ35_CANGA Q6FIY9_CANGA Q6FIY9_CANGA ATP23 ATP23 ATM1 ATM1 YME2 YME2 ATP8 ATP8 B4UN19_CANGA B4UN19_CANGA B4UN10_CANGA B4UN10_CANGA B4UN07_CANGA B4UN07_CANGA B4UMY3_CANGA B4UMY3_CANGA B4UMY0_CANGA B4UMY0_CANGA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CYT1Cytochrome c domain-containing protein. (299 aa)
Q6FY46_CANGAUncharacterized protein; Belongs to the AAA ATPase family. (457 aa)
COX12Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (83 aa)
Q6FY97_CANGAUbiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (268 aa)
Q6FY98_CANGAYL1_C domain-containing protein. (437 aa)
Q6FYA4_CANGASuccinate dehydrogenase [ubiquinone] cytochrome b small subunit. (181 aa)
Q6FYB1_CANGAUncharacterized protein. (115 aa)
URA9Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. (439 aa)
COX3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (269 aa)
ATP9ATP synthase subunit 9, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (76 aa)
ATP6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (260 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (534 aa)
COBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (385 aa)
Q6FY44_CANGAUncharacterized protein. (101 aa)
ATP22Mitochondrial translation factor ATP22; Translation factor specific for subunit 6 of the mitochondrial ATPase. Required for assembly of the CF(0) component of the ATPase (By similarity); Belongs to the ATP22 family. (573 aa)
Q6FXW3_CANGAUncharacterized protein. (69 aa)
Q6FXW2_CANGAUncharacterized protein. (801 aa)
Q6FXM7_CANGAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
Q6FXJ4_CANGAABC1 domain-containing protein. (585 aa)
SYM1Protein SYM1; May be involved in cellular response to stress. Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. (210 aa)
Q6FXC0_CANGARRM domain-containing protein. (275 aa)
MGR1Mitochondrial inner membrane i-AAA protease complex subunit MGR1; Component of the mitochondrial inner membrane i-AAA protease complex required for mitochondrial inner membrane protein turnover. (483 aa)
Q6FX67_CANGAMICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (88 aa)
Q6FWY1_CANGAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (329 aa)
ATP10Mitochondrial ATPase complex subunit ATP10; Involved in assembly of the mitochondrial F1-F0 complex. Belongs to the ATP10 family. (273 aa)
Q6FWU2_CANGAUncharacterized protein. (379 aa)
SDH2Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (253 aa)
Q6FWR3_CANGAUncharacterized protein. (440 aa)
Q6FWQ7_CANGAUncharacterized protein. (288 aa)
ATP16ATP-synt_DE_N domain-containing protein. (154 aa)
COX9Cytochrome c oxidase subunit 9, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (60 aa)
Q6FW91_CANGACOX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (104 aa)
Q6FW87_CANGAUncharacterized protein. (470 aa)
Q6FW68_CANGAJ domain-containing protein. (143 aa)
COX16Cytochrome c oxidase assembly protein COX16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family. (118 aa)
MIA40Mitochondrial intermembrane space import and assembly protein 40; Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond [...] (404 aa)
RRG8Required for respiratory growth protein 8, mitochondrial; Required for respiratory activity and maintenance and expression of the mitochondrial genome; Belongs to the RRG8 family. (260 aa)
Q6FVX7_CANGALetm1 RBD domain-containing protein. (433 aa)
Q6FVW7_CANGATafazzin family protein; Belongs to the taffazin family. (368 aa)
Q6FVP0_CANGAUncharacterized protein. (608 aa)
Q6FVF1_CANGAPolyketide_cyc domain-containing protein. (195 aa)
Q6FV90_CANGASuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (256 aa)
Q6FV78_CANGAUncharacterized protein. (499 aa)
MRS2Mitochondrial inner membrane magnesium transporter MRS2; High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix. Essential for the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing. It also suppresses a variety of mitochondrial intron mutations and its absence may disturb the assembly of mitochondrial membrane complexes. (456 aa)
Q6FUW0_CANGAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
Q6FUR6_CANGALetm1 RBD domain-containing protein. (543 aa)
Q6FUQ4_CANGAUncharacterized protein. (952 aa)
Q6FUE0_CANGAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa)
Q6FUC4_CANGAUncharacterized protein. (453 aa)
Q6FUA3_CANGAUncharacterized protein. (293 aa)
COQ4Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (330 aa)
Q6FU83_CANGAUncharacterized protein. (373 aa)
Q6FU68_CANGASuccinate dehydrogenase [ubiquinone] cytochrome b small subunit. (163 aa)
Q6FU64_CANGAPeptidase_S24 domain-containing protein. (171 aa)
CCS1Superoxide dismutase 1 copper chaperone; Copper chaperone for superoxide dismutase 1 (SOD1). Binds copper ions and delivers them specifically to SOD1 (By similarity). (239 aa)
Q6FU32_CANGAUncharacterized protein. (222 aa)
Q6FU14_CANGAUncharacterized protein. (98 aa)
Q6FU13_CANGAABC1 domain-containing protein. (414 aa)
Q6FTZ1_CANGAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (368 aa)
Q6FTY1_CANGAMICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (235 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (477 aa)
Q6FTI1_CANGAPeptidase_M48 domain-containing protein. (344 aa)
TPC1Mitochondrial thiamine pyrophosphate carrier 1; Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
Q6FTB4_CANGAUncharacterized protein. (310 aa)
PAM16Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. (146 aa)
RRG1Required for respiratory growth protein 1, mitochondrial; Essential for respiratory growth and required for mitochondrial protein synthesis. Required for vacuolar acidification (By similarity); Belongs to the RRG1 family. (377 aa)
TIM22Mitochondrial import inner membrane translocase subunit TIM22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (193 aa)
MIC27MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (238 aa)
Q6FSY7_CANGAUncharacterized protein. (330 aa)
RCF1Respiratory supercomplex factor 1, mitochondrial; Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes. (158 aa)
MIC60MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity). (520 aa)
Q6FSU3_CANGARhomboid domain-containing protein. (341 aa)
QCR2Cytochrome b-c1 complex subunit 2, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradie [...] (364 aa)
QCR7Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inn [...] (128 aa)
Q6FSE9_CANGADUF155 domain-containing protein. (361 aa)
ATP5ATP synthase subunit 5, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (207 aa)
Q6FS91_CANGAUncharacterized protein. (802 aa)
Q6FS56_CANGAMitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (132 aa)
Q6FS17_CANGAUncharacterized protein. (56 aa)
TIM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity). (485 aa)
ATP4ATP synthase subunit 4, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (242 aa)
Q6FRU6_CANGAUncharacterized protein. (113 aa)
INA17Inner membrane assembly complex subunit 17; Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase. INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain. (164 aa)
Q6FRU2_CANGALactamase_B domain-containing protein. (446 aa)
TIM9Mitochondrial import inner membrane translocase subunit TIM9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (87 aa)
Q6FRQ5_CANGAUncharacterized protein. (180 aa)
Q6FRH4_CANGAzf-Tim10_DDP domain-containing protein. (101 aa)
Q6FRE0_CANGAUncharacterized protein. (69 aa)
Q6FRD6_CANGAAAA domain-containing protein. (750 aa)
Q6FRD2_CANGAProtoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (538 aa)
Q6FR99_CANGAUncharacterized protein. (373 aa)
Q6FR66_CANGAUncharacterized protein. (105 aa)
Q6FR61_CANGAMitochondrial inner membrane protease subunit. (189 aa)
Q6FR47_CANGAUncharacterized protein. (343 aa)
Q6FQZ1_CANGAOBG-type G domain-containing protein. (543 aa)
Q6FQY2_CANGAUncharacterized protein; Belongs to the FMO family. (431 aa)
Q6FQS1_CANGAUncharacterized protein. (287 aa)
Q6FQP5_CANGAUncharacterized protein. (565 aa)
Q6FQN6_CANGAThioredoxin domain-containing protein. (294 aa)
Q6FQK3_CANGAMitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (212 aa)
Q6FQI7_CANGAMitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (161 aa)
Q6FQH1_CANGAUncharacterized protein. (94 aa)
Q6FQG9_CANGAUncharacterized protein. (623 aa)
NUC1Endonuclease. (322 aa)
Q6FQG0_CANGAUncharacterized protein. (386 aa)
Q6FQF9_CANGAUncharacterized protein. (276 aa)
Q6FQE7_CANGAUncharacterized protein. (503 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (299 aa)
AIM5MICOS complex subunit MIC12; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (114 aa)
Q6FPZ9_CANGAProhibitin. (288 aa)
COX6Uncharacterized protein. (152 aa)
Q6FPU5_CANGASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (710 aa)
PAM18Mitochondrial import inner membrane translocase subunit TIM14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity); Belongs to the TIM14 family. (153 aa)
ATP25ATPase synthesis protein 25, mitochondrial; Probable mitochondrial mRNA stabilization factor. Belongs to the ATP25 family. (623 aa)
Q6FPT0_CANGAG domain-containing protein. (351 aa)
Q6FPS4_CANGAAAA domain-containing protein. (827 aa)
Q6FPN3_CANGAMitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (412 aa)
PET117Uncharacterized protein. (127 aa)
Q6FPJ6_CANGAAMP_N domain-containing protein. (487 aa)
mge1GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity). (231 aa)
Q6FPG0_CANGAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (303 aa)
Q6FPF5_CANGAUncharacterized protein. (522 aa)
TIM54Mitochondrial import inner membrane translocase subunit TIM54; Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as external driving force (By similarity). (452 aa)
PSD1Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (508 aa)
Q6FN98_CANGAUncharacterized protein. (403 aa)
Q6FN64_CANGAUncharacterized protein. (123 aa)
Q6FN44_CANGAUncharacterized protein. (78 aa)
Q6FN43_CANGAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (342 aa)
Q6FN13_CANGAUncharacterized protein. (485 aa)
TIM21Mitochondrial import inner membrane translocase subunit TIM21; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity). (215 aa)
Q6FMX2_CANGAUncharacterized protein. (317 aa)
PURA_CANGAAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (432 aa)
Q6FMU6_CANGAAAA domain-containing protein. (745 aa)
Q6FMN6_CANGAUncharacterized protein. (512 aa)
MDM32Mitochondrial distribution and morphology protein 32; Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures (By similarity). Belongs to the MDM31/MDM32 family. (649 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (232 aa)
Q6FM68_CANGAUncharacterized protein. (161 aa)
Q6FM52_CANGAUncharacterized protein. (67 aa)
FMN1Riboflavin kinase; Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme; Belongs to the flavokinase family. (189 aa)
Q6FM36_CANGACytochrome c oxidase assembly protein COX20, mitochondrial; Involved in the assembly of the cytochrome c oxidase complex. Belongs to the COX20 family. (185 aa)
Q6FM23_CANGAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
Q6FLW8_CANGAUncharacterized protein. (205 aa)
Q6FLN4_CANGAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (297 aa)
Q6FLK2_CANGAUncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (891 aa)
Q6FLH9_CANGAUncharacterized protein. (366 aa)
HEM15Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (378 aa)
Q6FLB5_CANGAAB hydrolase-1 domain-containing protein. (451 aa)
Q6FLB3_CANGASURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (374 aa)
SUN4Uncharacterized protein. (346 aa)
Q6FL51_CANGAUncharacterized protein. (154 aa)
Q6FL49_CANGAUncharacterized protein; Belongs to the cytochrome c oxidase subunit 6A family. (128 aa)
Q6FL37_CANGAProhibitin. (313 aa)
AEP3ATPase expression protein 3; Required for respiration. (623 aa)
ATP7ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (176 aa)
Q6FY45_CANGANADPH:adrenodoxin oxidoreductase, mitochondrial. (501 aa)
Q6FKA2_CANGAUncharacterized protein. (573 aa)
SHE9Sensitive to high expression protein 9 homolog, mitochondrial; Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed (By similarity). (405 aa)
Q6FJY1_CANGAUncharacterized protein. (285 aa)
Q6FJQ3_CANGAUncharacterized protein. (711 aa)
PAM17Presequence translocated-associated motor subunit PAM17, mitochondrial; Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. (186 aa)
Q6FJG9_CANGAUncharacterized protein. (284 aa)
Q6FJD4_CANGAUncharacterized protein. (585 aa)
LPE10Mitochondrial inner membrane magnesium transporter LPE10; Mitochondrial inner membrane magnesium transporter required for mitochondrial magnesium homeostasis. Modulates the conductance of the MRS2 channel. Involved in the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing. (397 aa)
Q6FJB8_CANGATrmE-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (487 aa)
Q6FJA1_CANGAUncharacterized protein. (108 aa)
Q6FJ35_CANGA4HBT domain-containing protein. (242 aa)
Q6FIY9_CANGAHIG1 domain-containing protein. (225 aa)
ATP23Mitochondrial inner membrane protease ATP23; Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity); Belongs to the peptidase M76 family. (225 aa)
ATM1Iron-sulfur clusters transporter ATM1, mitochondrial; Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Hydrolyzes ATP. Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity). (727 aa)
YME2Mitochondrial escape protein 2; Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA (By similarity); Belongs to the YME2 family. (848 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (48 aa)
B4UN19_CANGAUncharacterized protein. (63 aa)
B4UN10_CANGAUncharacterized protein. (90 aa)
B4UN07_CANGAUncharacterized protein. (61 aa)
B4UMY3_CANGAUncharacterized protein. (73 aa)
B4UMY0_CANGAUncharacterized protein. (149 aa)
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
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