STRINGSTRING
Q6FVW7_CANGA Q6FVW7_CANGA Q6FVU0_CANGA Q6FVU0_CANGA CYM1 CYM1 Q6FUE0_CANGA Q6FUE0_CANGA Q6FTP2_CANGA Q6FTP2_CANGA PAM16 PAM16 TIM22 TIM22 TIM50 TIM50 TIM9 TIM9 Q6FRH4_CANGA Q6FRH4_CANGA TIM13 TIM13 COX23 COX23 Q6FQP5_CANGA Q6FQP5_CANGA DLD1 DLD1 Q6FQK3_CANGA Q6FQK3_CANGA Q6FQI7_CANGA Q6FQI7_CANGA Q6FPY5_CANGA Q6FPY5_CANGA PAM18 PAM18 Q6FPN3_CANGA Q6FPN3_CANGA mge1 mge1 Q6FP21_CANGA Q6FP21_CANGA Q6FNU5_CANGA Q6FNU5_CANGA Q6FNH3_CANGA Q6FNH3_CANGA TIM21 TIM21 Q6FMT4_CANGA Q6FMT4_CANGA HSP60 HSP60 Q6FLU3_CANGA Q6FLU3_CANGA MGM101 MGM101 B4UMZ9_CANGA B4UMZ9_CANGA YFH1 YFH1 TIM8 TIM8 Q6FY46_CANGA Q6FY46_CANGA Q6FXV4_CANGA Q6FXV4_CANGA Q6FXT1_CANGA Q6FXT1_CANGA Q6FW68_CANGA Q6FW68_CANGA MIA40 MIA40
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Q6FVW7_CANGATafazzin family protein; Belongs to the taffazin family. (368 aa)
Q6FVU0_CANGAUncharacterized protein. (55 aa)
CYM1Mitochondrial presequence protease; ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides (By similarity); Belongs to the peptidase M16 family. PreP subfamily. (990 aa)
Q6FUE0_CANGAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa)
Q6FTP2_CANGASulfhydryl oxidase. (174 aa)
PAM16Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. (146 aa)
TIM22Mitochondrial import inner membrane translocase subunit TIM22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (193 aa)
TIM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity). (485 aa)
TIM9Mitochondrial import inner membrane translocase subunit TIM9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (87 aa)
Q6FRH4_CANGAzf-Tim10_DDP domain-containing protein. (101 aa)
TIM13Mitochondrial import inner membrane translocase subunit TIM13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (95 aa)
COX23Cytochrome c oxidase-assembly factor COX23, mitochondrial; Required for the assembly of cytochrome c oxidase. Belongs to the COX23 family. (111 aa)
Q6FQP5_CANGAUncharacterized protein. (565 aa)
DLD1FAD-binding PCMH-type domain-containing protein. (574 aa)
Q6FQK3_CANGAMitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (212 aa)
Q6FQI7_CANGAMitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (161 aa)
Q6FPY5_CANGAUncharacterized protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (326 aa)
PAM18Mitochondrial import inner membrane translocase subunit TIM14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity); Belongs to the TIM14 family. (153 aa)
Q6FPN3_CANGAMitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (412 aa)
mge1GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity). (231 aa)
Q6FP21_CANGAUncharacterized protein. (957 aa)
Q6FNU5_CANGAUncharacterized protein. (86 aa)
Q6FNH3_CANGAUncharacterized protein. (159 aa)
TIM21Mitochondrial import inner membrane translocase subunit TIM21; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity). (215 aa)
Q6FMT4_CANGASulfhydryl oxidase. (207 aa)
HSP60Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (568 aa)
Q6FLU3_CANGAUncharacterized protein. (847 aa)
MGM101Mitochondrial genome maintenance protein MGM101; Performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome. Binds to DNA (By similarity); Belongs to the MGM101 family. (244 aa)
B4UMZ9_CANGAzf-Tim10_DDP domain-containing protein. (93 aa)
YFH1Uncharacterized protein. (176 aa)
TIM8Mitochondrial import inner membrane translocase subunit TIM8; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (87 aa)
Q6FY46_CANGAUncharacterized protein; Belongs to the AAA ATPase family. (457 aa)
Q6FXV4_CANGAJ domain-containing protein. (198 aa)
Q6FXT1_CANGACOX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (101 aa)
Q6FW68_CANGAJ domain-containing protein. (143 aa)
MIA40Mitochondrial intermembrane space import and assembly protein 40; Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond [...] (404 aa)
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.