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TIF45 | Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures; Belongs to the eukaryotic initiation factor 4E family. (209 aa) | ||||
ADE2 | Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (570 aa) | ||||
URA3 | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (265 aa) | ||||
PAB1 | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] (579 aa) |