STRINGSTRING
ADE2 ADE2 Q6FIK4_CANGA Q6FIK4_CANGA Q6FIM3_CANGA Q6FIM3_CANGA PYK1 PYK1 Q6FJW8_CANGA Q6FJW8_CANGA ADK2 ADK2 Q6FKU4_CANGA Q6FKU4_CANGA ISN1 ISN1 Q6FLM3_CANGA Q6FLM3_CANGA ADK1 ADK1 Q6FM59_CANGA Q6FM59_CANGA Q6FMI7_CANGA Q6FMI7_CANGA PGM1 PGM1 Q6FMP8_CANGA Q6FMP8_CANGA PURA_CANGA PURA_CANGA Q6FMX3_CANGA Q6FMX3_CANGA Q6FN21_CANGA Q6FN21_CANGA Q6FN58_CANGA Q6FN58_CANGA Q6FNM6_CANGA Q6FNM6_CANGA Q6FNV3_CANGA Q6FNV3_CANGA AAH1 AAH1 Q6FPK3_CANGA Q6FPK3_CANGA Q6FQK6_CANGA Q6FQK6_CANGA Q6FQQ2_CANGA Q6FQQ2_CANGA Q6FQV0_CANGA Q6FQV0_CANGA Q6FRC2_CANGA Q6FRC2_CANGA Q6FRK3_CANGA Q6FRK3_CANGA Q6FSW0_CANGA Q6FSW0_CANGA APT1 APT1 Q6FT98_CANGA Q6FT98_CANGA Q6FTA1_CANGA Q6FTA1_CANGA GUA1 GUA1 Q6FUK4_CANGA Q6FUK4_CANGA HPT1 HPT1 HAM1 HAM1 PYK2 PYK2 Q6FW29_CANGA Q6FW29_CANGA Q6FW40_CANGA Q6FW40_CANGA Q6FWF7_CANGA Q6FWF7_CANGA Q6FWH8_CANGA Q6FWH8_CANGA Q6FWJ5_CANGA Q6FWJ5_CANGA ADO1 ADO1 Q6FX60_CANGA Q6FX60_CANGA Q6FXH8_CANGA Q6FXH8_CANGA MET3 MET3 Q6FY79_CANGA Q6FY79_CANGA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADE2Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (570 aa)
Q6FIK4_CANGAAmidophosphoribosyltransferase. (513 aa)
Q6FIM3_CANGANucleoside diphosphate kinase. (152 aa)
PYK1Pyruvate kinase 1. (501 aa)
Q6FJW8_CANGAUncharacterized protein. (617 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (251 aa)
Q6FKU4_CANGADHHA2 domain-containing protein. (380 aa)
ISN1IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family. (447 aa)
Q6FLM3_CANGAAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (207 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (222 aa)
Q6FM59_CANGAInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (527 aa)
Q6FMI7_CANGANudix hydrolase domain-containing protein. (229 aa)
PGM1Uncharacterized protein; Belongs to the phosphohexose mutase family. (567 aa)
Q6FMP8_CANGAGuanylate kinase-like domain-containing protein. (185 aa)
PURA_CANGAAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (432 aa)
Q6FMX3_CANGAGlutamine amidotransferase type-1 domain-containing protein. (1346 aa)
Q6FN21_CANGAUncharacterized protein; Belongs to the phosphohexose mutase family. (568 aa)
Q6FN58_CANGAPribosyltran_N domain-containing protein. (321 aa)
Q6FNM6_CANGAPribosyltran domain-containing protein. (196 aa)
Q6FNV3_CANGAPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (315 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (347 aa)
Q6FPK3_CANGARibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (894 aa)
Q6FQK6_CANGAPribosyltran_N domain-containing protein. (319 aa)
Q6FQQ2_CANGASAICAR_synt domain-containing protein. (306 aa)
Q6FQV0_CANGAAdenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (212 aa)
Q6FRC2_CANGAUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (634 aa)
Q6FRK3_CANGAATP-grasp domain-containing protein. (791 aa)
Q6FSW0_CANGAA_deaminase domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (758 aa)
APT1Pribosyltran domain-containing protein. (190 aa)
Q6FT98_CANGAUncharacterized protein. (335 aa)
Q6FTA1_CANGABis(5'-adenosyl)-triphosphatase. (190 aa)
GUA1GMP synthase [glutamine-hydrolyzing]. (525 aa)
Q6FUK4_CANGAFormyl_trans_N domain-containing protein. (210 aa)
HPT1Pribosyltran domain-containing protein. (215 aa)
HAM1Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (192 aa)
PYK2Pyruvate kinase 2. (508 aa)
Q6FW29_CANGAUncharacterized protein. (400 aa)
Q6FW40_CANGAUncharacterized protein. (2082 aa)
Q6FWF7_CANGAPribosyltran_N domain-containing protein. (429 aa)
Q6FWH8_CANGAGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (483 aa)
Q6FWJ5_CANGAPribosyltran_N domain-containing protein. (481 aa)
ADO1PfkB domain-containing protein. (338 aa)
Q6FX60_CANGAATP_transf domain-containing protein. (318 aa)
Q6FXH8_CANGAAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. Belongs to the sulfate adenylyltransferase family. (507 aa)
Q6FY79_CANGAMGS domain-containing protein. (590 aa)
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
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