STRINGSTRING
AGOS_AGR137W AGOS_AGR137W AGOS_AGR101C AGOS_AGR101C AGOS_AGL101C AGOS_AGL101C AGOS_AFR458C AGOS_AFR458C AGOS_AFR456C AGOS_AFR456C MUS81 MUS81 AGOS_AFL159W AGOS_AFL159W AGOS_AER387C AGOS_AER387C AGOS_AER008W AGOS_AER008W AGOS_AEL020W AGOS_AEL020W AGOS_AEL218W AGOS_AEL218W AGOS_ADR025W AGOS_ADR025W MPH1 MPH1 AGOS_ADL351W AGOS_ADL351W
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGOS_AGR137WAGR137Wp. (503 aa)
AGOS_AGR101CAGR101Cp; Belongs to the RecA family. (333 aa)
AGOS_AGL101CDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (631 aa)
AGOS_AFR458CAFR458Cp. (215 aa)
AGOS_AFR456CAFR456Cp. (1015 aa)
MUS81Crossover junction endonuclease MUS81; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (604 aa)
AGOS_AFL159WAFL159Wp. (1323 aa)
AGOS_AER387CAER387Cp. (655 aa)
AGOS_AER008WAER008Wp. (510 aa)
AGOS_AEL020WAEL020Wp. (551 aa)
AGOS_AEL218WAEL218Wp. (1471 aa)
AGOS_ADR025WADR025Wp. (364 aa)
MPH1ATP-dependent DNA helicase MPH1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork. Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily. (1077 aa)
AGOS_ADL351WADL351Wp. (199 aa)
Your Current Organism:
Eremothecium gossypii
NCBI taxonomy Id: 284811
Other names: Ashbya gossypii ATCC 10895, E. gossypii ATCC 10895, Eremothecium gossypii ATCC 10895
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