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| | ALG14 | UDP-N-acetylglucosamine transferase subunit ALG14; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER (By similarity). (224 aa) |
| | AGOS_AGL156W | AGL156Wp. (910 aa) |
| | AGOS_AGL169C | AGL169Cp. (252 aa) |
| | DCN1 | Defective in cullin neddylation protein 1; May contribute to neddylation of cullin components of SCF- type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity). (255 aa) |
| | AGOS_AAR138C | AAR138Cp. (368 aa) |
| | AGOS_ABL129W | ABL129Wp. (345 aa) |
| | AGOS_ABR006W | ABR006Wp. (97 aa) |
| | AGOS_ABL012C | E3 ubiquitin-protein ligase PEP5. (1021 aa) |
| | AGOS_ABR047W | ABR047Wp; Belongs to the adaptor complexes medium subunit family. (498 aa) |
| | SEC17 | Vesicular-fusion protein SEC17; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus; Belongs to the SNAP family. (291 aa) |
| | SRB4 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (639 aa) |
| | BOS1 | Protein transport protein BOS1; SNARE required for protein transport between the ER and the Golgi complex; Belongs to the BOS1 family. (220 aa) |
| | YPT35 | PX domain-containing protein YPT35; Belongs to the YPT35 family. (171 aa) |
| | AGOS_ACL067C | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (219 aa) |
| | GET2 | Golgi to ER traffic protein 2; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP- dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. (289 aa) |
| | AGOS_ACR072C | 26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (990 aa) |
| | AGOS_ACR083C | ACR083Cp. (375 aa) |
| | AGOS_ACR092C | ACR092Cp; Belongs to the syntaxin family. (274 aa) |
| | AGOS_ACR097W | ACR097Wp. (467 aa) |
| | AGOS_ACR114C | ACR114Cp. (234 aa) |
| | AGOS_ACR130W | ACR130Wp. (570 aa) |
| | AGOS_ACR230C | ACR230Cp. (398 aa) |
| | AGOS_ACR275W | ACR275Wp. (263 aa) |
| | LDB19 | Protein LDB19; May be involved in protein-linked oligosaccharide phosphorylation; Belongs to the LDB19 family. (684 aa) |
| | AGOS_ADL302W | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (957 aa) |
| | AGOS_ADL119W | ADL119Wp. (185 aa) |
| | AGOS_ADL181W | ADL181Wp. (109 aa) |
| | AGOS_ADL118C | Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (418 aa) |
| | AGOS_ADL100W | ADL100Wp. (147 aa) |
| | AGOS_ADL082C | ADL082Cp. (568 aa) |
| | AGOS_ADL061W | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa) |
| | AGOS_ADL056W | ADL056Wp. (807 aa) |
| | AGOS_ADR106W | ADR106Wp; Belongs to the cullin family. (798 aa) |
| | AGOS_ADL022C | ADL022Cp. (3392 aa) |
| | AGOS_ADL017C | ADL017Cp; Belongs to the adaptor complexes medium subunit family. (443 aa) |
| | AGOS_ADL007C | ADL007Cp. (135 aa) |
| | AGOS_ADR007C | ADR007Cp. (354 aa) |
| | AGOS_ADR064C | AP-1 complex subunit gamma. (791 aa) |
| | AGOS_ADR065W | ADR065Wp. (912 aa) |
| | AGOS_ADR172C | ADR172Cp. (658 aa) |
| | AGOS_ADR182W | ADR182Wp. (585 aa) |
| | AGOS_ADR211W | ADR211Wp. (600 aa) |
| | PEX3 | Peroxisomal biogenesis factor 3; Involved in peroxisome biosynthesis; Belongs to the peroxin-3 family. (446 aa) |
| | AGOS_ADR315W | ADR315Wp; Belongs to the adaptor complexes medium subunit family. (455 aa) |
| | AGOS_ADR331C | ADR331Cp. (1561 aa) |
| | AGOS_ADR355C | ADR355Cp. (109 aa) |
| | MED8 | Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (223 aa) |
| | AGOS_AEL241W | AEL241Wp. (549 aa) |
| | AGOS_AEL107W | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (889 aa) |
| | VAC8 | Vacuolar protein 8; Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole; Belongs to the beta-catenin family. (568 aa) |
| | AGOS_AEL026C | AEL026Cp; Belongs to the syntaxin family. (349 aa) |
| | AGOS_AER049W | AER049Wp. (857 aa) |
| | ART10 | Arrestin-related trafficking adapter 10; May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli; Belongs to the ART10 family. (430 aa) |
| | YKT6 | Synaptobrevin homolog YKT6. (200 aa) |
| | AGOS_AER114W | Coronin; Belongs to the WD repeat coronin family. (633 aa) |
| | AGOS_AER132W | AER132Wp. (232 aa) |
| | AGOS_AER173C | AER173Cp; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | AGOS_AER236C | AER236Cp. (392 aa) |
| | AGOS_AER307W | AER307Wp. (591 aa) |
| | AGOS_AER398W | AER398Wp. (1150 aa) |
| | END3 | Actin cytoskeleton-regulatory complex protein END3; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (372 aa) |
| | AGOS_AER438C | AER438Cp. (348 aa) |
| | AGOS_AFL232W | AFL232Wp; Belongs to the syntaxin family. (274 aa) |
| | ATG16 | Autophagy protein 16; Stabilizes the ATG5-ATG12 conjugate which is necessary for autophagy. The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS). Recruits also ATG3 to the PAS. Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity). (124 aa) |
| | AGOS_AFL168W | AFL168Wp. (215 aa) |
| | AGOS_AFL139W | AFL139Wp; Belongs to the syntaxin family. (297 aa) |
| | AGOS_AFL043C | AFL043Cp. (254 aa) |
| | DDI1 | DNA damage-inducible protein 1; Probable aspartic protease. May be involved in the regulation of exocytosis. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control. (472 aa) |
| | AGOS_AFR101C | AFR101Cp. (972 aa) |
| | RIM8 | pH-response regulator protein palF/RIM8; Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. (548 aa) |
| | AGOS_AFR124W | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (156 aa) |
| | AGOS_AFR210C | AFR210Cp; Belongs to the syntaxin family. (329 aa) |
| | AGOS_AGL144C | Kinase; Belongs to the inositol phosphokinase (IPK) family. (339 aa) |
| | AGOS_AGR067W | AGR067Wp. (1125 aa) |
| | AGOS_AGL024W | AGL024Wp. (756 aa) |
| | AGOS_AGR011W | AGR011Wp. (304 aa) |
| | AGOS_AGR054C | AGR054Cp. (233 aa) |
| | AGOS_AGR069C | AGR069Cp. (632 aa) |
| | AGOS_AGR147W | AGR147Wp. (766 aa) |
| | AGOS_AGR170C | AGR170Cp. (1121 aa) |
| | SEC22 | Protein transport protein SEC22; Required for transport from the ER to the Golgi complex. Belongs to the synaptobrevin family. (214 aa) |
| | AGOS_AGR312W | AGR312Wp. (616 aa) |
| | AGOS_AGR378C | AGR378Cp. (117 aa) |
| | AGOS_AGR381C | AGR381Cp. (335 aa) |
| | AGOS_AFR225W | AFR225Wp. (1299 aa) |
| | IRC6 | Increased recombination centers protein 6; Involved in gross chromosomal rearrangements (GCRs) and telomere healing. (304 aa) |
| | AGOS_AFR344C | AFR344Cp. (293 aa) |
| | AGOS_AFR358W | AFR358Wp. (413 aa) |
| | AGOS_AFR370C | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (146 aa) |
| | AGOS_AFR375W | AFR375Wp. (189 aa) |
| | AGOS_AFR411C | Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family. (283 aa) |
| | YAE1 | Protein YAE1; The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation. (144 aa) |
| | AGOS_AFR581C | AFR581Cp. (514 aa) |
| | PEX5 | Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. (569 aa) |
| | SEC9 | Protein transport protein SEC9; Belongs to the SNAP-25 family. (533 aa) |
| | AGOS_AFR498W | AFR498Wp; Belongs to the cullin family. (727 aa) |
| | FIP1 | Pre-mRNA polyadenylation factor FIP1; Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase; Belongs to the FIP1 family. (323 aa) |
| | SHO1 | High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (330 aa) |
| | ELC1 | Elongin-C; Prevents degradation of interacting proteins by the proteasome. (100 aa) |
| | AGOS_AGL235C | AGL235Cp. (185 aa) |
