STRINGSTRING
AGOS_ACR248W AGOS_ACR248W AGOS_ACR203W AGOS_ACR203W MRPL44 MRPL44 COB COB COX1 COX1 AGOS_AGR393W AGOS_AGR393W AGOS_AGR392C AGOS_AGR392C AGOS_AGR362C AGOS_AGR362C AGOS_AGR361W AGOS_AGR361W PPE1 PPE1 AGOS_AGR345C AGOS_AGR345C AGOS_AGR323C AGOS_AGR323C AGOS_AGR311C AGOS_AGR311C AGOS_AGR295C AGOS_AGR295C AGOS_AGR193C AGOS_AGR193C AGOS_AGR103W AGOS_AGR103W AGOS_AGR081C AGOS_AGR081C AGOS_AGR080W AGOS_AGR080W RSM10 RSM10 AGOS_AGR024C AGOS_AGR024C AGOS_AGL013W AGOS_AGL013W AGOS_AGL059C AGOS_AGL059C SDH4 SDH4 AGOS_AGL138C AGOS_AGL138C AGOS_AGL140C AGOS_AGL140C AGOS_AGL200W AGOS_AGL200W AGOS_AGL211C AGOS_AGL211C AGOS_AGL216W AGOS_AGL216W AGOS_AGL222W AGOS_AGL222W AGOS_AGL224W AGOS_AGL224W AGOS_AGL240W AGOS_AGL240W AGOS_AGL272C AGOS_AGL272C AGOS_AGL284C AGOS_AGL284C ATP8L_ASHGO ATP8L_ASHGO AGOS_AGL317C AGOS_AGL317C MIC10 MIC10 QCR7 QCR7 MGR1 MGR1 AGOS_AFR635C AGOS_AFR635C AGOS_AFR618C AGOS_AFR618C AIM5 AIM5 AGOS_AFR564W AGOS_AFR564W AGOS_AFR523C AGOS_AFR523C AGOS_AFR463C AGOS_AFR463C AGOS_AFR450C AGOS_AFR450C AGOS_AFR448W AGOS_AFR448W AGOS_AFR405W AGOS_AFR405W AGOS_AFR313C AGOS_AFR313C AGOS_AFR403W AGOS_AFR403W AGOS_AFR260C AGOS_AFR260C AGOS_AFR240C AGOS_AFR240C AGOS_AFR207C AGOS_AFR207C AGOS_AFR202W AGOS_AFR202W AGOS_AFR197W AGOS_AFR197W AGOS_AFR196C AGOS_AFR196C AGOS_AFR193W AGOS_AFR193W AGOS_AFR137C AGOS_AFR137C MIC60 MIC60 PAM16 PAM16 AGOS_AFR062C AGOS_AFR062C AGOS_AFR091W AGOS_AFR091W AGOS_AFL074C AGOS_AFL074C AGOS_AFL089C AGOS_AFL089C AGOS_AFL106C AGOS_AFL106C AGOS_AFL111W AGOS_AFL111W AGOS_AFL156W AGOS_AFL156W AGOS_AFL162C AGOS_AFL162C AGOS_AFL183C AGOS_AFL183C MDM34 MDM34 AGOS_AER403C AGOS_AER403C MIC27 MIC27 AGOS_AER374C AGOS_AER374C AGOS_AER365W AGOS_AER365W AGOS_AER364W AGOS_AER364W AGOS_AER316C AGOS_AER316C AGOS_AER207C AGOS_AER207C MRP10 MRP10 AGOS_AER163W AGOS_AER163W AGOS_AER262C AGOS_AER262C MRPL4 MRPL4 AGOS_AER103W AGOS_AER103W AGOS_AER062C AGOS_AER062C MRPS9 MRPS9 AGOS_AER021C AGOS_AER021C mge1 mge1 AGOS_ACR080C AGOS_ACR080C AGOS_ACR069C AGOS_ACR069C AGOS_ACR064W AGOS_ACR064W AGOS_ACR052W AGOS_ACR052W AGOS_ACR021W AGOS_ACR021W MDM12 MDM12 AGOS_ACR014C AGOS_ACR014C SDH2 SDH2 AGOS_ACL097C AGOS_ACL097C AGOS_ACL110W AGOS_ACL110W AGOS_ACL141C AGOS_ACL141C AGOS_ACL176W AGOS_ACL176W QCR2 QCR2 TIM21 TIM21 AGOS_ABR191C AGOS_ABR191C INA17 INA17 AGOS_ABR169W AGOS_ABR169W AGOS_ABR148W AGOS_ABR148W AGOS_ABR146W AGOS_ABR146W AGOS_ABR133W AGOS_ABR133W AGOS_ABR086W AGOS_ABR086W AGOS_ABR065W AGOS_ABR065W AGOS_ABR010C AGOS_ABR010C AGOS_ABR003W AGOS_ABR003W AGOS_ABL041W AGOS_ABL041W ATP16 ATP16 TIM9 TIM9 AGOS_AEL067W AGOS_AEL067W AGOS_AEL078C AGOS_AEL078C AGOS_AEL097C AGOS_AEL097C AGOS_AEL119W AGOS_AEL119W AGOS_AEL121W AGOS_AEL121W AGOS_AEL162W AGOS_AEL162W AGOS_AEL167C AGOS_AEL167C TIM54 TIM54 AGOS_AEL116C AGOS_AEL116C AGOS_AEL206C AGOS_AEL206C ATP4 ATP4 AGOS_AEL318W AGOS_AEL318W MRPL51 MRPL51 MDM10 MDM10 GEM1 GEM1 AGOS_ADR357C AGOS_ADR357C PAM18 PAM18 PAM17 PAM17 AGOS_ADR283W AGOS_ADR283W AGOS_ADR240C AGOS_ADR240C AGOS_ADR223C AGOS_ADR223C AGOS_ADR208W AGOS_ADR208W TIM10 TIM10 TIM8 TIM8 AGOS_ABL111C AGOS_ABL111C AGOS_ABL136C AGOS_ABL136C AGOS_ABL144C AGOS_ABL144C TIM22 TIM22 AGOS_AAR167C AGOS_AAR167C AGOS_AAR128W AGOS_AAR128W AGOS_AAR108WA AGOS_AAR108WA AGOS_AAR106C AGOS_AAR106C AGOS_AAR070C AGOS_AAR070C AGOS_AAR067W AGOS_AAR067W AGOS_AAR061W AGOS_AAR061W AGOS_AAR027W AGOS_AAR027W AGOS_AAR025C AGOS_AAR025C AGOS_AAR002W AGOS_AAR002W MRPL2 MRPL2 AGOS_AAR117C AGOS_AAR117C FYV4 FYV4 ATP5 ATP5 MHR1 MHR1 AGOS_AAL111C AGOS_AAL111C TIM13 TIM13 AGOS_AAL145W AGOS_AAL145W MMM1 MMM1 COX3 COX3 ATP9 ATP9 ATP6 ATP6 ATP8 ATP8 VAR1 VAR1 COX2 COX2 MRP2 MRP2 AGOS_ADR136C AGOS_ADR136C ARG2 ARG2 AGOS_ADR269C AGOS_ADR269C TIM50 TIM50 AGOS_ADL023W AGOS_ADL023W AGOS_ADL025W AGOS_ADL025W AGOS_ADL117W AGOS_ADL117W AGOS_ADL118C AGOS_ADL118C AGOS_ADL124C AGOS_ADL124C AGOS_ADL129W AGOS_ADL129W AGOS_ADL130W AGOS_ADL130W AGOS_ADL141W AGOS_ADL141W AGOS_ADL146W AGOS_ADL146W AGOS_ADL167W AGOS_ADL167W RSM25 RSM25 AGOS_ADL223W AGOS_ADL223W AGOS_ADL243W AGOS_ADL243W MRP51 MRP51 AGOS_ADL304W AGOS_ADL304W AGOS_ADL311W AGOS_ADL311W AGOS_ADL357C AGOS_ADL357C AGOS_ADL375W AGOS_ADL375W AGOS_ADL372W AGOS_ADL372W AGOS_ACR224C AGOS_ACR224C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AGOS_ACR248WMitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (156 aa)
AGOS_ACR203WACR203Wp. (100 aa)
MRPL4454S ribosomal protein L44, mitochondrial; Component of the large subunit of mitochondrial ribosome. Belongs to the mitochondrion-specific ribosomal protein mL53 family. (98 aa)
COBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (384 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (535 aa)
AGOS_AGR393WAGR393Wp. (142 aa)
AGOS_AGR392CAGR392Cp. (495 aa)
AGOS_AGR362CAGR362Cp. (90 aa)
AGOS_AGR361WAGR361Wp. (355 aa)
PPE1Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit (By similarity); Belongs to the AB hydrolase superfamily. (385 aa)
AGOS_AGR345CAGR345Cp. (150 aa)
AGOS_AGR323CAGR323Cp. (402 aa)
AGOS_AGR311CAGR311Cp. (339 aa)
AGOS_AGR295CAGR295Cp. (117 aa)
AGOS_AGR193CAGR193Cp. (232 aa)
AGOS_AGR103WPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (408 aa)
AGOS_AGR081CAGR081Cp. (130 aa)
AGOS_AGR080WAGR080Wp. (275 aa)
RSM1037S ribosomal protein S10, mitochondrial; Involved in mitochondrial genome encoded proteins translation. Involved in the binding of tRNA to the ribosomes (By similarity). (207 aa)
AGOS_AGR024C3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (477 aa)
AGOS_AGL013WAGL013Wp. (118 aa)
AGOS_AGL059CAGL059Cp. (81 aa)
SDH4Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (171 aa)
AGOS_AGL138CAGL138Cp; Belongs to the peptidase M16 family. (470 aa)
AGOS_AGL140C37S ribosomal protein S24, mitochondrial; Involved in mitochondrial genome encoded proteins translation; Belongs to the mitochondrion-specific ribosomal protein mS35 family. (303 aa)
AGOS_AGL200WAGL200Wp. (436 aa)
AGOS_AGL211CAGL211Cp. (612 aa)
AGOS_AGL216WAGL216Wp. (61 aa)
AGOS_AGL222WAGL222Wp; Belongs to the universal ribosomal protein uS12 family. (160 aa)
AGOS_AGL224WAGL224Wp; Belongs to the universal ribosomal protein uS19 family. (91 aa)
AGOS_AGL240WAGL240Wp. (708 aa)
AGOS_AGL272CATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (547 aa)
AGOS_AGL284CAGL284Cp. (144 aa)
ATP8L_ASHGOPutative ATP synthase protein 8-like protein. (48 aa)
AGOS_AGL317CAGL317Cp. (251 aa)
MIC10MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (82 aa)
QCR7Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inn [...] (126 aa)
MGR1Mitochondrial inner membrane i-AAA protease complex subunit MGR1; Component of the mitochondrial inner membrane i-AAA protease complex required for mitochondrial inner membrane protein turnover. (395 aa)
AGOS_AFR635CAFR635Cp. (267 aa)
AGOS_AFR618CAFR618Cp. (145 aa)
AIM5MICOS complex subunit MIC12; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (94 aa)
AGOS_AFR564WAFR564Wp; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (334 aa)
AGOS_AFR523CSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit. (180 aa)
AGOS_AFR463CAFR463Cp. (142 aa)
AGOS_AFR450CAFR450Cp; Belongs to the universal ribosomal protein uL30 family. (84 aa)
AGOS_AFR448WAFR448Wp. (918 aa)
AGOS_AFR405WAFR405Wp. (244 aa)
AGOS_AFR313CProhibitin. (283 aa)
AGOS_AFR403WAFR403Wp; Belongs to the universal ribosomal protein uL13 family. (156 aa)
AGOS_AFR260CAFR260Cp. (119 aa)
AGOS_AFR240CAFR240Cp. (136 aa)
AGOS_AFR207CAFR207Cp. (166 aa)
AGOS_AFR202WAFR202Wp. (133 aa)
AGOS_AFR197WAFR197Wp. (474 aa)
AGOS_AFR196CAFR196Cp; Belongs to the cytochrome c oxidase subunit 6A family. (126 aa)
AGOS_AFR193WAFR193Wp. (153 aa)
AGOS_AFR137CIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (367 aa)
MIC60MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity). (496 aa)
PAM16Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. (136 aa)
AGOS_AFR062CAFR062Cp. (473 aa)
AGOS_AFR091WAFR091Wp. (159 aa)
AGOS_AFL074CMitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (121 aa)
AGOS_AFL089CAFL089Cp. (166 aa)
AGOS_AFL106CAFL106Cp. (440 aa)
AGOS_AFL111WAFL111Wp. (328 aa)
AGOS_AFL156WAFL156Wp. (232 aa)
AGOS_AFL162CAFL162Cp. (261 aa)
AGOS_AFL183CAFL183Cp. (386 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (590 aa)
AGOS_AER403CAER403Cp. (480 aa)
MIC27MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (236 aa)
AGOS_AER374CAER374Cp. (1004 aa)
AGOS_AER365WAER365Wp. (60 aa)
AGOS_AER364WAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (453 aa)
AGOS_AER316CAER316Cp. (269 aa)
AGOS_AER207CAER207Cp. (151 aa)
MRP1037S ribosomal protein MRP10, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (95 aa)
AGOS_AER163WAER163Wp. (60 aa)
AGOS_AER262CAER262Cp. (172 aa)
MRPL454S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL29 family. (341 aa)
AGOS_AER103WAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (123 aa)
AGOS_AER062CAER062Cp. (71 aa)
MRPS937S ribosomal protein S9, mitochondrial. (279 aa)
AGOS_AER021CAER021Cp. (65 aa)
mge1GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity). (212 aa)
AGOS_ACR080CACR080Cp. (58 aa)
AGOS_ACR069CACR069Cp. (491 aa)
AGOS_ACR064WACR064Wp. (709 aa)
AGOS_ACR052WSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (633 aa)
AGOS_ACR021WACR021Wp. (62 aa)
MDM12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (264 aa)
AGOS_ACR014CACR014Cp. (70 aa)
SDH2Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (261 aa)
AGOS_ACL097CATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (174 aa)
AGOS_ACL110WACL110Wp. (149 aa)
AGOS_ACL141CACL141Cp. (123 aa)
AGOS_ACL176WATP synthase subunit gamma. (290 aa)
QCR2Cytochrome b-c1 complex subunit 2, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradie [...] (366 aa)
TIM21Mitochondrial import inner membrane translocase subunit TIM21; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity). (234 aa)
AGOS_ABR191CABR191Cp. (112 aa)
INA17Inner membrane assembly complex subunit 17; Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase. INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain. (159 aa)
AGOS_ABR169WATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (505 aa)
AGOS_ABR148WABR148Wp. (289 aa)
AGOS_ABR146WABR146Wp. (445 aa)
AGOS_ABR133W50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (96 aa)
AGOS_ABR086WABR086Wp. (168 aa)
AGOS_ABR065WABR065Wp. (344 aa)
AGOS_ABR010CABR010Cp; Belongs to the universal ribosomal protein uS2 family. (391 aa)
AGOS_ABR003WABR003Wp. (130 aa)
AGOS_ABL041WABL041Wp. (818 aa)
ATP16ATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (158 aa)
TIM9Mitochondrial import inner membrane translocase subunit TIM9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (87 aa)
AGOS_AEL067WCytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (212 aa)
AGOS_AEL078CAEL078Cp. (291 aa)
AGOS_AEL097CAEL097Cp; Belongs to the universal ribosomal protein uS15 family. (281 aa)
AGOS_AEL119WAEL119Wp; Belongs to the universal ribosomal protein uL14 family. (138 aa)
AGOS_AEL121WAEL121Wp. (94 aa)
AGOS_AEL162WAEL162Wp; Belongs to the bacterial ribosomal protein bL17 family. (236 aa)
AGOS_AEL167CAEL167Cp. (101 aa)
TIM54Mitochondrial import inner membrane translocase subunit TIM54; Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as external driving force (By similarity). (472 aa)
AGOS_AEL116CAEL116Cp. (129 aa)
AGOS_AEL206CAEL206Cp. (180 aa)
ATP4ATP synthase subunit 4, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (236 aa)
AGOS_AEL318WAEL318Wp. (181 aa)
MRPL5154S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL43 family. (142 aa)
MDM10Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (465 aa)
GEM1Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. (661 aa)
AGOS_ADR357CADR357Cp. (1131 aa)
PAM18Mitochondrial import inner membrane translocase subunit TIM14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity); Belongs to the TIM14 family. (158 aa)
PAM17Presequence translocated-associated motor subunit PAM17, mitochondrial; Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. (186 aa)
AGOS_ADR283WADR283Wp. (155 aa)
AGOS_ADR240CCytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (79 aa)
AGOS_ADR223CADR223Cp. (202 aa)
AGOS_ADR208WADR208Wp. (296 aa)
TIM10Mitochondrial import inner membrane translocase subunit TIM10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (89 aa)
TIM8Mitochondrial import inner membrane translocase subunit TIM8; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (87 aa)
AGOS_ABL111CABL111Cp. (291 aa)
AGOS_ABL136CABL136Cp; Belongs to the universal ribosomal protein uL22 family. (303 aa)
AGOS_ABL144CABL144Cp; Belongs to the universal ribosomal protein uL11 family. (149 aa)
TIM22Mitochondrial import inner membrane translocase subunit TIM22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (201 aa)
AGOS_AAR167CPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
AGOS_AAR128WAAR128Wp. (385 aa)
AGOS_AAR108WAAAR108W-Ap. (70 aa)
AGOS_AAR106CAAR106Cp. (50 aa)
AGOS_AAR070CMitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (267 aa)
AGOS_AAR067WAAR067Wp. (190 aa)
AGOS_AAR061WAAR061Wp. (143 aa)
AGOS_AAR027WAAR027Wp; Belongs to the universal ribosomal protein uS5 family. (316 aa)
AGOS_AAR025CAAR025Cp. (726 aa)
AGOS_AAR002WAAR002Wp. (178 aa)
MRPL254S ribosomal protein L2, mitochondrial; Component of the large subunit of mitochondrial ribosome. Belongs to the bacterial ribosomal protein bL27 family. (359 aa)
AGOS_AAR117CAAR117Cp. (296 aa)
FYV4Protein FYV4, mitochondrial; Involved in telomere length regulation; Belongs to the mitochondrion-specific ribosomal protein mS41 family. (122 aa)
ATP5ATP synthase subunit 5, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (207 aa)
MHR1Mitochondrial homologous recombination protein 1; Transcription factor involved in regulation of RNA polymerase II-dependent transcription. Also involved in regulation of mitochondrial DNA recombination, maintenance and repair, and generation of homoplasmic cells (By similarity); Belongs to the mitochondrion-specific ribosomal protein mL67 family. (213 aa)
AGOS_AAL111CAAL111Cp. (293 aa)
TIM13Mitochondrial import inner membrane translocase subunit TIM13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (103 aa)
AGOS_AAL145WAAL145Wp. (66 aa)
MMM1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (444 aa)
COX3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (269 aa)
ATP9ATP synthase subunit 9, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (76 aa)
ATP6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (263 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (48 aa)
VAR1Ribosomal protein VAR1, mitochondrial; Essential for mitochondrial protein synthesis and required for the maturation of small ribosomal subunits. (339 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (248 aa)
MRP237S ribosomal protein MRP2, mitochondrial. (114 aa)
AGOS_ADR136CADR136Cp. (284 aa)
ARG2Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (542 aa)
AGOS_ADR269CMitochondrial inner membrane protease subunit. (194 aa)
TIM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity). (476 aa)
AGOS_ADL023WADL023Wp. (228 aa)
AGOS_ADL025WADL025Wp. (119 aa)
AGOS_ADL117WADL117Wp. (173 aa)
AGOS_ADL118CMitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (418 aa)
AGOS_ADL124CADL124Cp. (126 aa)
AGOS_ADL129WADL129Wp; Belongs to the universal ribosomal protein uL3 family. (267 aa)
AGOS_ADL130WADL130Wp; Belongs to the universal ribosomal protein uL6 family. (214 aa)
AGOS_ADL141WProhibitin. (307 aa)
AGOS_ADL146WMICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (222 aa)
AGOS_ADL167WADL167Wp. (199 aa)
RSM2537S ribosomal protein S25, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS23 family. (258 aa)
AGOS_ADL223WIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (362 aa)
AGOS_ADL243WADL243Wp. (150 aa)
MRP5137S ribosomal protein MRP51, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (360 aa)
AGOS_ADL304WADL304Wp; Belongs to the universal ribosomal protein uL16 family. (220 aa)
AGOS_ADL311WADL311Wp. (102 aa)
AGOS_ADL357CADL357Cp. (1176 aa)
AGOS_ADL375WADL375Wp. (172 aa)
AGOS_ADL372WADL372Wp. (156 aa)
AGOS_ACR224CDNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1295 aa)
Your Current Organism:
Eremothecium gossypii
NCBI taxonomy Id: 284811
Other names: Ashbya gossypii ATCC 10895, E. gossypii ATCC 10895, Eremothecium gossypii ATCC 10895
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