STRINGSTRING
AGOS_AAR176C AGOS_AAR176C MIM1_ASHGO MIM1_ASHGO AGOS_AGR392C AGOS_AGR392C AGOS_AGR348W AGOS_AGR348W AGOS_AGR345C AGOS_AGR345C AGOS_AGR254C AGOS_AGR254C AGOS_AGR177C AGOS_AGR177C AGOS_AGR084C AGOS_AGR084C ERG27 ERG27 AGOS_AGR021C AGOS_AGR021C AGOS_AGR003W AGOS_AGR003W AGOS_AGL066W AGOS_AGL066W AGOS_AGL211C AGOS_AGL211C BNA4 BNA4 AGOS_AFR680W AGOS_AFR680W AGOS_AFR555W AGOS_AFR555W AGOS_AFR544W AGOS_AFR544W ERG9 ERG9 ALO1 ALO1 AGOS_AFR439C AGOS_AFR439C AGOS_AFR381C AGOS_AFR381C AGOS_AFR373W AGOS_AFR373W NCA2 NCA2 AGOS_AFR295W AGOS_AFR295W ATG32 ATG32 AGOS_AFR148W AGOS_AFR148W SEN34 SEN34 AGOS_AFL152W AGOS_AFL152W AGOS_AFL183C AGOS_AFL183C MDM34 MDM34 AGOS_AER428W AGOS_AER428W AGOS_AER403C AGOS_AER403C AGOS_AER365W AGOS_AER365W AGOS_AER357C AGOS_AER357C AGOS_AEL018C AGOS_AEL018C AGOS_AEL161W AGOS_AEL161W TSC10 TSC10 AGOS_AEL242W AGOS_AEL242W AGOS_AEL275C AGOS_AEL275C MDV1 MDV1 AGOS_AEL317C AGOS_AEL317C AGOS_AEL318W AGOS_AEL318W AGOS_AEL332W AGOS_AEL332W MDM10 MDM10 GEM1 GEM1 AGOS_ADR303W AGOS_ADR303W ERG6 ERG6 AGOS_ADR182W AGOS_ADR182W AGOS_ADR136C AGOS_ADR136C FMP52 FMP52 FIS1 FIS1 AGOS_ADL061W AGOS_ADL061W CBR1 CBR1 AGOS_ADL185W AGOS_ADL185W AGOS_ACR231C AGOS_ACR231C AGOS_ACR164C AGOS_ACR164C AGOS_ACR149C AGOS_ACR149C AGOS_ACR114C AGOS_ACR114C AGOS_ACR080C AGOS_ACR080C MCR1 MCR1 MDM12 MDM12 AGOS_ACL018W AGOS_ACL018W AGOS_ACL062C AGOS_ACL062C AGOS_ABR210W AGOS_ABR210W AGOS_ABR195C AGOS_ABR195C AGOS_ABR194C AGOS_ABR194C AGOS_ABR163W AGOS_ABR163W AGOS_ABR131W AGOS_ABR131W AGOS_ABR036W AGOS_ABR036W AGOS_ABL001W AGOS_ABL001W AGOS_AAR106C AGOS_AAR106C AGOS_AAR037W AGOS_AAR037W NCP1 NCP1 AGOS_AAL152W AGOS_AAL152W AGOS_AAL174C AGOS_AAL174C MMM1 MMM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGOS_AAR176CAAR176Cp. (153 aa)
MIM1_ASHGOMitochondrial import protein 1; Required for the assembly of the TOM (translocase of outer membrane) receptor complex, which is responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins; Belongs to the MIM1 family. (155 aa)
AGOS_AGR392CAGR392Cp. (495 aa)
AGOS_AGR348WAGR348Wp. (551 aa)
AGOS_AGR345CAGR345Cp. (150 aa)
AGOS_AGR254CTafazzin family protein; Belongs to the taffazin family. (395 aa)
AGOS_AGR177CAGR177Cp. (485 aa)
AGOS_AGR084CAGR084Cp. (427 aa)
ERG273-keto-steroid reductase; Responsible for the reduction of the keto group on the C-3 of sterols. (348 aa)
AGOS_AGR021CAGR021Cp. (387 aa)
AGOS_AGR003WAGR003Wp. (518 aa)
AGOS_AGL066WAGL066Wp. (450 aa)
AGOS_AGL211CAGL211Cp. (612 aa)
BNA4Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (466 aa)
AGOS_AFR680WAFR680Wp. (461 aa)
AGOS_AFR555WAFR555Wp. (146 aa)
AGOS_AFR544WAFR544Wp. (337 aa)
ERG9Squalene synthase; Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. Required for the biosynthesis of ergosterol (By similarity); Belongs to the phytoene/squalene synthase family. (441 aa)
ALO1D-arabinono-1,4-lactone oxidase; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (532 aa)
AGOS_AFR439CNADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (310 aa)
AGOS_AFR381CAFR381Cp. (384 aa)
AGOS_AFR373WAFR373Wp. (467 aa)
NCA2Nuclear control of ATPase protein 2; Involved in the mitochondrial expression of subunits 6 and 8 of the F0-F1 ATP synthase. (569 aa)
AGOS_AFR295WGlycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (631 aa)
ATG32Autophagy-related protein 32; Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Promotes also autophagy- dependent peroxisome degradation (By similarity); Belongs to the ATG32 family. (452 aa)
AGOS_AFR148WAFR148Wp. (92 aa)
SEN34tRNA-splicing endonuclease subunit SEN34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (292 aa)
AGOS_AFL152WAFL152Wp. (425 aa)
AGOS_AFL183CAFL183Cp. (386 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (590 aa)
AGOS_AER428WAER428Wp. (498 aa)
AGOS_AER403CAER403Cp. (480 aa)
AGOS_AER365WAER365Wp. (60 aa)
AGOS_AER357CCDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (276 aa)
AGOS_AEL018CAEL018Cp. (383 aa)
AGOS_AEL161WAEL161Wp. (356 aa)
TSC103-ketodihydrosphingosine reductase TSC10; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (307 aa)
AGOS_AEL242WAEL242Wp; Belongs to the peptidase C19 family. (613 aa)
AGOS_AEL275CDolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (265 aa)
MDV1Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family. (715 aa)
AGOS_AEL317CAEL317Cp. (162 aa)
AGOS_AEL318WAEL318Wp. (181 aa)
AGOS_AEL332WAEL332Wp. (205 aa)
MDM10Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (465 aa)
GEM1Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. (661 aa)
AGOS_ADR303WADR303Wp. (310 aa)
ERG6Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (373 aa)
AGOS_ADR182WADR182Wp. (585 aa)
AGOS_ADR136CADR136Cp. (284 aa)
FMP52Protein FMP52, mitochondrial. (224 aa)
FIS1Mitochondrial fission 1 protein; Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity). (155 aa)
AGOS_ADL061WActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
CBR1NADH-cytochrome b5 reductase 1; Electron donor reductase for cytochrome b5. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes (By similarity). (287 aa)
AGOS_ADL185WADL185Wp. (477 aa)
AGOS_ACR231CACR231Cp. (479 aa)
AGOS_ACR164CACR164Cp; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (868 aa)
AGOS_ACR149CACR149Cp. (455 aa)
AGOS_ACR114CACR114Cp. (234 aa)
AGOS_ACR080CACR080Cp. (58 aa)
MCR1NADH-cytochrome b5 reductase 2; May mediate the reduction of outer membrane cytochrome b5. Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (306 aa)
MDM12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (264 aa)
AGOS_ACL018WACL018Wp. (134 aa)
AGOS_ACL062CACL062Cp. (382 aa)
AGOS_ABR210WABR210Wp. (208 aa)
AGOS_ABR195CABR195Cp; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (808 aa)
AGOS_ABR194CABR194Cp. (450 aa)
AGOS_ABR163WCAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (453 aa)
AGOS_ABR131WABR131Wp. (594 aa)
AGOS_ABR036WABR036Wp; Belongs to the AAA ATPase family. (360 aa)
AGOS_ABL001WABL001Wp; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (685 aa)
AGOS_AAR106CAAR106Cp. (50 aa)
AGOS_AAR037WCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (262 aa)
NCP1NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (688 aa)
AGOS_AAL152WAAL152Wp. (787 aa)
AGOS_AAL174CAAL174Cp; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (756 aa)
MMM1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (444 aa)
Your Current Organism:
Eremothecium gossypii
NCBI taxonomy Id: 284811
Other names: Ashbya gossypii ATCC 10895, E. gossypii ATCC 10895, Eremothecium gossypii ATCC 10895
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