STRINGSTRING
AGOS_AEL204C AGOS_AEL204C AGOS_AGR364C AGOS_AGR364C AGOS_AGR273C AGOS_AGR273C AGOS_AGR238C AGOS_AGR238C AGOS_AGR166W AGOS_AGR166W AGOS_AGR149W AGOS_AGR149W AGOS_AGL014C AGOS_AGL014C AGOS_AGL044C AGOS_AGL044C AGOS_AGL022W AGOS_AGL022W AGOS_AGL076W AGOS_AGL076W AGOS_AGL086C AGOS_AGL086C AGOS_AGL094W AGOS_AGL094W AGOS_AGL113C AGOS_AGL113C SCC2 SCC2 AGOS_AGL147C AGOS_AGL147C AGOS_AGL078W AGOS_AGL078W AGOS_AGL298C AGOS_AGL298C AGOS_AGL305W AGOS_AGL305W AGOS_AGL349C AGOS_AGL349C CWC22 CWC22 AGOS_AGL364C AGOS_AGL364C AGOS_AFR669W AGOS_AFR669W AGOS_AFR666C AGOS_AFR666C LIA1 LIA1 LOS1 LOS1 AGOS_AFR420W AGOS_AFR420W AGOS_AFR396W AGOS_AFR396W AGOS_AFR342C AGOS_AFR342C AGOS_AFR301C AGOS_AFR301C AGOS_AFR273W AGOS_AFR273W AGOS_AFR269W AGOS_AFR269W AGOS_AFR200W AGOS_AFR200W AGOS_AFR169W AGOS_AFR169W CBC1 CBC1 UTP10 UTP10 AGOS_AFL020W AGOS_AFL020W AGOS_AFL068C AGOS_AFL068C APL5 APL5 AGOS_AFL131W AGOS_AFL131W AGOS_AFL147C AGOS_AFL147C AGOS_AFL222W AGOS_AFL222W AGOS_AER400C AGOS_AER400C AGOS_AER393C AGOS_AER393C AGOS_AER389C AGOS_AER389C AGOS_AER378W AGOS_AER378W AGOS_AER377C AGOS_AER377C AGOS_AER359W AGOS_AER359W EFR3 EFR3 TOM1 TOM1 AGOS_AER273C AGOS_AER273C AGOS_AER219C AGOS_AER219C AGOS_AER174W AGOS_AER174W AGOS_AER284W AGOS_AER284W AGOS_AER093C AGOS_AER093C AGOS_AER055W AGOS_AER055W AGOS_AER049W AGOS_AER049W AGOS_AER045C AGOS_AER045C AGOS_AEL006W AGOS_AEL006W VAC8 VAC8 AGOS_AEL061W AGOS_AEL061W AGOS_AEL094C AGOS_AEL094C AGOS_AEL193W AGOS_AEL193W AGOS_AEL194W AGOS_AEL194W AGOS_AEL256C AGOS_AEL256C AGOS_AEL333W AGOS_AEL333W AGOS_ADR378W AGOS_ADR378W AGOS_ADR342C AGOS_ADR342C APL6 APL6 AGOS_ADR334W AGOS_ADR334W AGOS_ADR331C AGOS_ADR331C AGOS_ADR292W AGOS_ADR292W IPI1 IPI1 AGOS_ADR064C AGOS_ADR064C AGOS_ADL033W AGOS_ADL033W AGOS_ADL056W AGOS_ADL056W AGOS_ADL093W AGOS_ADL093W AGOS_ADL128C AGOS_ADL128C AGOS_ADL233W AGOS_ADL233W AGOS_ADL277W AGOS_ADL277W STU1 STU1 AGOS_ADL302W AGOS_ADL302W AGOS_ADL316C AGOS_ADL316C FES1 FES1 AGOS_ACR279C AGOS_ACR279C AGOS_ACR181C AGOS_ACR181C AGOS_ACR159C AGOS_ACR159C AGOS_ACR072C AGOS_ACR072C NOP9 NOP9 AGOS_ACR032C AGOS_ACR032C AGOS_ACR020C AGOS_ACR020C RPN2 RPN2 AGOS_ACL063W AGOS_ACL063W AGOS_ACL132C AGOS_ACL132C AGOS_ACL187W AGOS_ACL187W AGOS_ABR214C AGOS_ABR214C MEC1 MEC1 AGOS_ABR035C AGOS_ABR035C AGOS_ABR013W AGOS_ABR013W AGOS_ABL068C AGOS_ABL068C RIX1 RIX1 AGOS_ABL112W AGOS_ABL112W AGOS_ABL150W AGOS_ABL150W AGOS_AAR140W AGOS_AAR140W AGOS_AAR115C AGOS_AAR115C CTR86 CTR86 TEF3 TEF3 AGOS_AAL150W AGOS_AAL150W AGOS_AAL152W AGOS_AAL152W
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGOS_AEL204CAEL204Cp. (1591 aa)
AGOS_AGR364CAGR364Cp. (1001 aa)
AGOS_AGR273CCondensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1158 aa)
AGOS_AGR238CAGR238Cp. (904 aa)
AGOS_AGR166WAGR166Wp. (1013 aa)
AGOS_AGR149WVacuolar protein sorting-associated protein 41; Required for vacuolar assembly and vacuolar traffic. Belongs to the VPS41 family. (885 aa)
AGOS_AGL014CAGL014Cp. (1212 aa)
AGOS_AGL044CAGL044Cp. (1023 aa)
AGOS_AGL022WAGL022Wp. (2145 aa)
AGOS_AGL076WAGL076Wp. (1268 aa)
AGOS_AGL086CAGL086Cp. (735 aa)
AGOS_AGL094WAGL094Wp. (731 aa)
AGOS_AGL113CPhosphatidylinositol 3-kinase VPS34. (870 aa)
SCC2Sister chromatid cohesion protein 2; Plays a structural role in chromatin. Probably involved in sister chromatid cohesion, possibly by interacting with the cohesin complex (By similarity); Belongs to the SCC2/Nipped-B family. (1479 aa)
AGOS_AGL147CAGL147Cp. (1896 aa)
AGOS_AGL078WAGL078Wp. (1037 aa)
AGOS_AGL298CAGL298Cp. (1115 aa)
AGOS_AGL305WAGL305Wp. (1057 aa)
AGOS_AGL349CAGL349Cp. (1092 aa)
CWC22Pre-mRNA-splicing factor CWC22; May be involved in pre-mRNA splicing. (554 aa)
AGOS_AGL364CAGL364Cp. (1260 aa)
AGOS_AFR669WAFR669Wp. (1959 aa)
AGOS_AFR666CAFR666Cp; Belongs to the PI3/PI4-kinase family. (997 aa)
LIA1Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. (322 aa)
LOS1Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity); Belongs to the exportin family. (1051 aa)
AGOS_AFR420WSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2462 aa)
AGOS_AFR396WAFR396Wp. (949 aa)
AGOS_AFR342CAFR342Cp. (649 aa)
AGOS_AFR301CAFR301Cp. (1655 aa)
AGOS_AFR273WAFR273Wp. (969 aa)
AGOS_AFR269WAFR269Wp. (1017 aa)
AGOS_AFR200WAP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (694 aa)
AGOS_AFR169WAFR169Wp. (2671 aa)
CBC1Nuclear cap-binding protein complex subunit 1; Component of the cap-binding complex (CBC) involved in the nuclear export of capped U snRNAs. The CBC complex is required for efficient pre-mRNA splicing through efficient commitment complex and spliceosome formation; and involved in rRNA processing at sites A0, A1 and A2 (By similarity). (860 aa)
UTP10U3 small nucleolar RNA-associated protein 10; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity). (1774 aa)
AGOS_AFL020WAFL020Wp. (504 aa)
AGOS_AFL068CAFL068Cp. (780 aa)
APL5AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole (By similarity). (899 aa)
AGOS_AFL131WAFL131Wp. (1190 aa)
AGOS_AFL147CAFL147Cp. (938 aa)
AGOS_AFL222WAFL222Wp. (732 aa)
AGOS_AER400CAER400Cp. (401 aa)
AGOS_AER393CAER393Cp; Belongs to the PI3/PI4-kinase family. (3697 aa)
AGOS_AER389CAER389Cp. (758 aa)
AGOS_AER378WAER378Wp. (2409 aa)
AGOS_AER377CAER377Cp. (1012 aa)
AGOS_AER359WClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1649 aa)
EFR3Protein EFR3; Belongs to the EFR3 family. (724 aa)
TOM1Probable E3 ubiquitin-protein ligase TOM1; Probable ubiquitin ligase protein, which may be involved in mRNA export. E3 ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. Participates in mRNA export from the nucleus by regulating the transport of hnRNP proteins; Belongs to the UPL family. TOM1/PTR1 subfamily. (3258 aa)
AGOS_AER273CAER273Cp. (1421 aa)
AGOS_AER219CAER219Cp. (909 aa)
AGOS_AER174WAER174Wp. (971 aa)
AGOS_AER284WAER284Wp. (1625 aa)
AGOS_AER093CAER093Cp. (362 aa)
AGOS_AER055WAER055Wp. (613 aa)
AGOS_AER049WAER049Wp. (857 aa)
AGOS_AER045CAER045Cp. (1292 aa)
AGOS_AEL006WAEL006Wp. (2491 aa)
VAC8Vacuolar protein 8; Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole; Belongs to the beta-catenin family. (568 aa)
AGOS_AEL061WAEL061Wp. (1393 aa)
AGOS_AEL094CAEL094Cp. (1221 aa)
AGOS_AEL193WCoatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (932 aa)
AGOS_AEL194WAEL194Wp. (373 aa)
AGOS_AEL256CAEL256Cp. (1866 aa)
AGOS_AEL333WSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (630 aa)
AGOS_ADR378WADR378Wp. (1021 aa)
AGOS_ADR342CAP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (697 aa)
APL6AP-3 complex subunit beta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole (By similarity). (781 aa)
AGOS_ADR334WADR334Wp. (956 aa)
AGOS_ADR331CADR331Cp. (1561 aa)
AGOS_ADR292WADR292Wp. (989 aa)
IPI1Pre-rRNA-processing protein IPI1; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA. (338 aa)
AGOS_ADR064CAP-1 complex subunit gamma. (791 aa)
AGOS_ADL033WADL033Wp; Belongs to the PI3/PI4-kinase family. (1916 aa)
AGOS_ADL056WADL056Wp. (807 aa)
AGOS_ADL093WADL093Wp. (1120 aa)
AGOS_ADL128CADL128Cp. (1082 aa)
AGOS_ADL233WLeucine aminopeptidase 2; Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro). (623 aa)
AGOS_ADL277WADL277Wp. (694 aa)
STU1Protein STU1; Microtubule binding protein that promotes the stabilization of dynamic microtubules. Required for mitotic spindle formation (By similarity). (1475 aa)
AGOS_ADL302WAP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (957 aa)
AGOS_ADL316CADL316Cp. (1411 aa)
FES1Hsp70 nucleotide exchange factor FES1; Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity). Belongs to the FES1 family. (289 aa)
AGOS_ACR279CACR279Cp. (603 aa)
AGOS_ACR181CV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (473 aa)
AGOS_ACR159CACR159Cp. (1025 aa)
AGOS_ACR072C26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (990 aa)
NOP9Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family. (678 aa)
AGOS_ACR032CNucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (680 aa)
AGOS_ACR020CACR020Cp. (1002 aa)
RPN226S proteasome regulatory subunit RPN2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (930 aa)
AGOS_ACL063WACL063Wp. (1850 aa)
AGOS_ACL132CACL132Cp. (954 aa)
AGOS_ACL187WACL187Wp. (861 aa)
AGOS_ABR214CABR214Cp. (1348 aa)
MEC1Serine/threonine-protein kinase MEC1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Recruited to DNA lesions in order to initiate the DNA repair by homologous recombination. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, also involved in the regulation of DNA damage response mechanism. Required for cell growth and meiotic recombina [...] (2324 aa)
AGOS_ABR035CABR035Cp. (980 aa)
AGOS_ABR013WABR013Wp. (1424 aa)
AGOS_ABL068CABL068Cp. (1041 aa)
RIX1Pre-rRNA-processing protein RIX1; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre- 60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1. (764 aa)
AGOS_ABL112WCoatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (971 aa)
AGOS_ABL150WImportin subunit alpha; Belongs to the importin alpha family. (543 aa)
AGOS_AAR140WAAR140Wp. (648 aa)
AGOS_AAR115CAAR115Cp. (964 aa)
CTR86Copper transport protein 86; Essential protein which may be involved in threonine biosynthesis; Belongs to the CTR86 family. (534 aa)
TEF3Elongation factor 3; The main role of EF-3 may be to transduce nucleoside triphosphate energy into mechanical energy for translocation during translation. EF-3 stimulates EF-1-alpha-dependent binding of aminoacyl- tRNA to the ribosome (By similarity); Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. (1044 aa)
AGOS_AAL150WAAL150Wp. (373 aa)
AGOS_AAL152WAAL152Wp. (787 aa)
Your Current Organism:
Eremothecium gossypii
NCBI taxonomy Id: 284811
Other names: Ashbya gossypii ATCC 10895, E. gossypii ATCC 10895, Eremothecium gossypii ATCC 10895
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