STRINGSTRING
AGOS_AGL113C AGOS_AGL113C AGOS_AGL144C AGOS_AGL144C PHO85 PHO85 SSN3 SSN3 TEL1 TEL1 AGOS_AFR716C AGOS_AFR716C AGOS_AFR666C AGOS_AFR666C AGOS_AFR647C AGOS_AFR647C RBK1 RBK1 AGOS_AFR420W AGOS_AFR420W AGOS_AFR387C AGOS_AFR387C PKH3 PKH3 DGK1 DGK1 AGOS_AFR279C AGOS_AFR279C AGOS_AFR205C AGOS_AFR205C GRC3 GRC3 AGOS_AFR092W AGOS_AFR092W CBK1 CBK1 AGOS_AFR019W AGOS_AFR019W AGOS_AFL090W AGOS_AFL090W AGOS_AFL091W AGOS_AFL091W IPL1 IPL1 AGOS_AFL188C AGOS_AFL188C AGOS_AFL185W AGOS_AFL185W AGOS_AER393C AGOS_AER393C AGOS_AER354W AGOS_AER354W AGOS_AER335W AGOS_AER335W AGOS_AER270W AGOS_AER270W AGOS_AER232C AGOS_AER232C AGOS_AER222C AGOS_AER222C AGOS_AER188C AGOS_AER188C AGOS_AER143W AGOS_AER143W AGOS_AER264C AGOS_AER264C AGOS_AER082W AGOS_AER082W PGK1 PGK1 AGOS_AEL083W AGOS_AEL083W HAL5_ASHGO HAL5_ASHGO AGOS_AEL115C AGOS_AEL115C AGOS_AEL208W AGOS_AEL208W AGOS_AEL230W AGOS_AEL230W ISR1 ISR1 AGOS_ADR379C AGOS_ADR379C PYK1 PYK1 AGOS_ADR288W AGOS_ADR288W AGOS_ADR253W AGOS_ADR253W AGOS_ADR204W AGOS_ADR204W AGOS_ADR164C AGOS_ADR164C AGOS_ADR163W AGOS_ADR163W AGOS_ADR058C AGOS_ADR058C AGOS_ADR033W AGOS_ADR033W AGOS_ADL033W AGOS_ADL033W AGOS_ADL053C AGOS_ADL053C AGOS_ADL062W AGOS_ADL062W AGOS_ADL086C AGOS_ADL086C AGOS_ADL102C AGOS_ADL102C AGOS_ADL116C AGOS_ADL116C AGOS_ADL168C AGOS_ADL168C AGOS_ADL315C AGOS_ADL315C AGOS_ADL389W AGOS_ADL389W AGOS_ADL283W AGOS_ADL283W AGOS_ACR218W AGOS_ACR218W AGOS_ACR191C AGOS_ACR191C URA6 URA6 AGOS_ACL006W AGOS_ACL006W AGOS_ACR142W AGOS_ACR142W ATG1 ATG1 AGOS_ACL069C AGOS_ACL069C AGOS_ACL150W AGOS_ACL150W AGOS_ACL191C AGOS_ACL191C BUR1 BUR1 MEC1 MEC1 NDK1 NDK1 STE20 STE20 AGOS_ABR001W AGOS_ABR001W AGOS_ABL011C AGOS_ABL011C AGOS_ABL028W AGOS_ABL028W FMN1 FMN1 NRK1 NRK1 CLA4 CLA4 IPK1 IPK1 AGOS_AAR009W AGOS_AAR009W AGOS_AAR157C AGOS_AAR157C AGOS_AAR184W AGOS_AAR184W BUD32 BUD32 ADK1 ADK1 ADK2 ADK2 ARO1 ARO1 AGOS_AGR058W AGOS_AGR058W HOG1 HOG1 YFH7 YFH7 AGOS_AGL096W AGOS_AGL096W
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
AGOS_AGL113CPhosphatidylinositol 3-kinase VPS34. (870 aa)
AGOS_AGL144CKinase; Belongs to the inositol phosphokinase (IPK) family. (339 aa)
PHO85Negative regulator of the PHO system; When phosphate concentrations are high it phosphorylates the PHO4 transcription factor thus establishing repression; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. (301 aa)
SSN3Serine/threonine-protein kinase SSN3; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity). (581 aa)
TEL1Serine/threonine-protein kinase TEL1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2768 aa)
AGOS_AFR716CPhosphotransferase. (493 aa)
AGOS_AFR666CAFR666Cp; Belongs to the PI3/PI4-kinase family. (997 aa)
AGOS_AFR647CFolic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. (820 aa)
RBK1Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (335 aa)
AGOS_AFR420WSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2462 aa)
AGOS_AFR387CThiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (347 aa)
PKH3Serine/threonine-protein kinase PKH3; Serine/threonine-protein kinase. (726 aa)
DGK1CTP-dependent diacylglycerol kinase 1; CTP-dependent diacylglycerol kinase that catalyzes the phosphorylation of diacylglycerol (DAG) to phosphatidate (PA). Controls phosphatidate levels at the nuclear envelope. May be involved in vesicle trafficking between the endoplasmic reticulum and the Golgi apparatus. Involved in pre-tRNA splicing (By similarity). Belongs to the DGK1 family. (317 aa)
AGOS_AFR279CPhosphotransferase. (488 aa)
AGOS_AFR205CAFR205Cp; Belongs to the protein kinase superfamily. (457 aa)
GRC3Polynucleotide 5'-hydroxyl-kinase GRC3; Polynucleotide 5'-kinase involved in rRNA processing. Belongs to the Clp1 family. NOL9/GRC3 subfamily. (633 aa)
AGOS_AFR092WAFR092Wp. (1423 aa)
CBK1Serine/threonine-protein kinase CBK1; Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation. (719 aa)
AGOS_AFR019WMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
AGOS_AFL090WAFL090Wp; Belongs to the protein kinase superfamily. (346 aa)
AGOS_AFL091WAFL091Wp; Belongs to the protein kinase superfamily. (478 aa)
IPL1Spindle assembly checkpoint kinase; Required for high-fidelity chromosome segregation during the later part of each cell cycle. Acts in opposition to the phosphatase PP1. Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles. The promotion of bi-orientation is achieved by selectively detaching kinetochore-microtubule attachments that are not under tension. Phosphorylates histone H3 to form H3S10ph during mitosis and meiosis (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Au [...] (367 aa)
AGOS_AFL188CAFL188Cp; Belongs to the protein kinase superfamily. (472 aa)
AGOS_AFL185WATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (958 aa)
AGOS_AER393CAER393Cp; Belongs to the PI3/PI4-kinase family. (3697 aa)
AGOS_AER354WPhosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (446 aa)
AGOS_AER335WMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (428 aa)
AGOS_AER270WProtein-serine/threonine kinase. (489 aa)
AGOS_AER232CMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (569 aa)
AGOS_AER222CAER222Cp; Belongs to the protein kinase superfamily. (423 aa)
AGOS_AER188CAER188Cp. (2174 aa)
AGOS_AER143WPhosphotransferase. (425 aa)
AGOS_AER264CMAP kinase kinase kinase. (1483 aa)
AGOS_AER082WInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1142 aa)
PGK1Phosphoglycerate kinase. (416 aa)
AGOS_AEL083WAEL083Wp. (536 aa)
HAL5_ASHGOProbable serine/threonine-protein kinase HAL5-like; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NPR/HAL subfamily. HAL5 sub-subfamily. (683 aa)
AGOS_AEL115CAEL115Cp; Belongs to the protein kinase superfamily. (386 aa)
AGOS_AEL208WATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (987 aa)
AGOS_AEL230WNon-specific serine/threonine protein kinase. (608 aa)
ISR1Serine/threonine-protein kinase ISR1; Probable serine/threonine protein kinase which may function redundantly with MPK1-independent branch of the PCK1 pathway. (342 aa)
AGOS_ADR379CADR379Cp; Belongs to the protein kinase superfamily. (475 aa)
PYK1Pyruvate kinase. (501 aa)
AGOS_ADR288WUridine kinase; Belongs to the uridine kinase family. (498 aa)
AGOS_ADR253WADR253Wp; Belongs to the protein kinase superfamily. (380 aa)
AGOS_ADR204WADR204Wp; Belongs to the protein kinase superfamily. (339 aa)
AGOS_ADR164CGluconokinase; Belongs to the gluconokinase GntK/GntV family. (199 aa)
AGOS_ADR163WADR163Wp; Belongs to the protein kinase superfamily. (426 aa)
AGOS_ADR058CADR058Cp; Belongs to the protein kinase superfamily. (295 aa)
AGOS_ADR033WNon-specific serine/threonine protein kinase. (577 aa)
AGOS_ADL033WADL033Wp; Belongs to the PI3/PI4-kinase family. (1916 aa)
AGOS_ADL053CADL053Cp; Belongs to the protein kinase superfamily. (471 aa)
AGOS_ADL062WADL062Wp; In the N-terminal section; belongs to the acetylglutamate kinase family. (855 aa)
AGOS_ADL086CAspartokinase. (552 aa)
AGOS_ADL102CADL102Cp; Belongs to the protein kinase superfamily. (372 aa)
AGOS_ADL116CProtein-serine/threonine kinase. (435 aa)
AGOS_ADL168CADL168Cp; Belongs to the protein kinase superfamily. (362 aa)
AGOS_ADL315CADL315Cp; Belongs to the protein kinase superfamily. (434 aa)
AGOS_ADL389WNon-specific serine/threonine protein kinase. (711 aa)
AGOS_ADL283WADL283Wp; Belongs to the protein kinase superfamily. (306 aa)
AGOS_ACR218WACR218Wp. (1568 aa)
AGOS_ACR191CProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1149 aa)
URA6Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (289 aa)
AGOS_ACL006WSerine/threonine-protein kinase. (709 aa)
AGOS_ACR142WSerine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. (847 aa)
ATG1Serine/threonine-protein kinase ATG1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...] (972 aa)
AGOS_ACL069CACL069Cp; Belongs to the FGGY kinase family. (644 aa)
AGOS_ACL150WAdenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (219 aa)
AGOS_ACL191CMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa)
BUR1Serine/threonine-protein kinase BUR1; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity). (753 aa)
MEC1Serine/threonine-protein kinase MEC1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Recruited to DNA lesions in order to initiate the DNA repair by homologous recombination. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, also involved in the regulation of DNA damage response mechanism. Required for cell growth and meiotic recombina [...] (2324 aa)
NDK1Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity); Belongs to the NDK family. (151 aa)
STE20Serine/threonine-protein kinase STE20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity). Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (970 aa)
AGOS_ABR001WAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (215 aa)
AGOS_ABL011CABL011Cp. (700 aa)
AGOS_ABL028WNon-specific serine/threonine protein kinase. (722 aa)
FMN1Riboflavin kinase; Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme; Belongs to the flavokinase family. (186 aa)
NRK1Nicotinamide riboside kinase; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN); Belongs to the uridine kinase family. NRK subfamily. (241 aa)
CLA4Serine/threonine-protein kinase CLA4; Required for hyphal maturation and for septation. (793 aa)
IPK1Inositol-pentakisphosphate 2-kinase; Has kinase activity and phosphorylates inositol-1,3,4,5,6- pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6- hexakisphosphate (InsP6), also known as phytate; Belongs to the IPK1 type 1 family. (278 aa)
AGOS_AAR009WAAR009Wp; Belongs to the protein kinase superfamily. (453 aa)
AGOS_AAR157CProtein-serine/threonine kinase. (503 aa)
AGOS_AAR184WKinase; Belongs to the inositol phosphokinase (IPK) family. (836 aa)
BUD32EKC/KEOPS complex subunit BUD32; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is r [...] (260 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (277 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (251 aa)
ARO13-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1577 aa)
AGOS_AGR058WNon-specific serine/threonine protein kinase. (1071 aa)
HOG1Mitogen-activated protein kinase HOG1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (447 aa)
YFH7ATP-dependent kinase YFH7; ATP-dependent kinase that could be involved in endoplasmic reticulum membrane assembly. (334 aa)
AGOS_AGL096WAGL096Wp. (547 aa)
Your Current Organism:
Eremothecium gossypii
NCBI taxonomy Id: 284811
Other names: Ashbya gossypii ATCC 10895, E. gossypii ATCC 10895, Eremothecium gossypii ATCC 10895
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