(28 nodes) Pyruvate metabolism network (Eremothecium gossypii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	AGOS_AGR103W	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (408 aa)
	ACS2	Acetyl-coenzyme A synthetase 2. (687 aa)
	AGOS_AGL068W	Malic enzyme. (621 aa)
	AGOS_AFR512W	Dihydrolipoyl dehydrogenase. (496 aa)
	PCK1	Phosphoenolpyruvate carboxykinase (ATP); Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (541 aa)
	ACH1	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation. (523 aa)
	AGOS_AFL201W	AFL201Wp; Belongs to the aldehyde dehydrogenase family. (497 aa)
	AGOS_AFL229W	AFL229Wp. (605 aa)
	AGOS_AER364W	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (453 aa)
	AGOS_AER321W	AER321Wp. (610 aa)
	AGOS_ADR417W	ADR417Wp; Belongs to the aldehyde dehydrogenase family. (507 aa)
	ACS1	Acetyl-coenzyme A synthetase 1; Belongs to the ATP-dependent AMP-binding enzyme family. (694 aa)
	PYK1	Pyruvate kinase. (501 aa)
	AGOS_ADR286C	ADR286Cp. (337 aa)
	AGOS_ADR252W	Malate dehydrogenase. (339 aa)
	AGOS_ADR165C	ADR165Cp; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
	AGOS_ADR152C	Malate dehydrogenase. (332 aa)
	AGOS_ADR107W	ADR107Wp; Belongs to the alpha-IPM synthase/homocitrate synthase family. (442 aa)
	AGOS_ADL015C	ADL015Cp. (578 aa)
	AGOS_ADL164C	ADL164Cp; Belongs to the LDH/MDH superfamily. (381 aa)
	AGOS_ACR268C	Malate synthase; Belongs to the malate synthase family. (552 aa)
	AGOS_ACR084C	ACR084Cp. (293 aa)
	AGOS_ACL021C	ACL021Cp. (534 aa)
	AGOS_ACR013C	ACR013Cp. (488 aa)
	AGOS_ACL044W	ACL044Wp; Belongs to the aldehyde dehydrogenase family. (513 aa)
	AGOS_AAR167C	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
	AGOS_AAR162C	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1171 aa)
	AGOS_AAR071W	AAR071Wp. (2231 aa)

Your Current Organism:

Eremothecium gossypii

NCBI taxonomy Id: 284811
Other names: Ashbya gossypii ATCC 10895, E. gossypii ATCC 10895, Eremothecium gossypii ATCC 10895

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACH1	ACS1	Q754Q2	Q758X0	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	Acetyl-coenzyme A synthetase 1; Belongs to the ATP-dependent AMP-binding enzyme family.	0.950
ACH1	ACS2	Q754Q2	Q750T7	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	Acetyl-coenzyme A synthetase 2.	0.950
ACH1	AGOS_AAR071W	Q754Q2	Q75EK8	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	AAR071Wp.	0.903
ACH1	AGOS_AAR162C	Q754Q2	Q75ED6	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.479
ACH1	AGOS_ACL044W	Q754Q2	Q75CG3	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	ACL044Wp; Belongs to the aldehyde dehydrogenase family.	0.930
ACH1	AGOS_ACR013C	Q754Q2	Q75CE3	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	ACR013Cp.	0.674
ACH1	AGOS_ACR268C	Q754Q2	Q75BK3	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	Malate synthase; Belongs to the malate synthase family.	0.962
ACH1	AGOS_ADL015C	Q754Q2	Q75AD2	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	ADL015Cp.	0.916
ACH1	AGOS_ADR107W	Q754Q2	Q75A20	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	ADR107Wp; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.916
ACH1	AGOS_ADR165C	Q754Q2	Q759V7	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	ADR165Cp; Belongs to the thiolase-like superfamily. Thiolase family.	0.948
ACH1	AGOS_ADR286C	Q754Q2	Q759J1	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	ADR286Cp.	0.723
ACH1	AGOS_ADR417W	Q754Q2	Q758W1	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	ADR417Wp; Belongs to the aldehyde dehydrogenase family.	0.930
ACH1	AGOS_AER364W	Q754Q2	Q756A3	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.918
ACH1	AGOS_AFL201W	Q754Q2	Q755L5	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	AFL201Wp; Belongs to the aldehyde dehydrogenase family.	0.930
ACH1	AGOS_AFL229W	Q754Q2	Q755P2	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	AFL229Wp.	0.916
ACH1	AGOS_AGL068W	Q754Q2	Q750Z9	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	Malic enzyme.	0.550
ACS1	ACH1	Q758X0	Q754Q2	Acetyl-coenzyme A synthetase 1; Belongs to the ATP-dependent AMP-binding enzyme family.	Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.	0.950
ACS1	ACS2	Q758X0	Q750T7	Acetyl-coenzyme A synthetase 1; Belongs to the ATP-dependent AMP-binding enzyme family.	Acetyl-coenzyme A synthetase 2.	0.939
ACS1	AGOS_AAR071W	Q758X0	Q75EK8	Acetyl-coenzyme A synthetase 1; Belongs to the ATP-dependent AMP-binding enzyme family.	AAR071Wp.	0.938
ACS1	AGOS_AAR162C	Q758X0	Q75ED6	Acetyl-coenzyme A synthetase 1; Belongs to the ATP-dependent AMP-binding enzyme family.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.880