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cyt2 cyt2 hem1 hem1 met8 met8 hem15 hem15 met1 met1 cyc3 cyc3 SPCC417.11c SPCC417.11c hem2 hem2 hem4 hem4 hem3 hem3 hem14 hem14 ymc1 ymc1 hem12 hem12 hem13 hem13 cox10 cox10 shy1 shy1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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cyt2Putative cytochrome c1 heme lyase; Involved in the final maturation of cytochrome c1, it links covalently the heme group to the apoprotein. (216 aa)
hem15-aminolevulinate synthase, mitochondrial; Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis. (558 aa)
met8Siroheme biosynthesis protein met8; Catalyzes the conversion of precorrin-2 into siroheme. This reaction consist of the NAD-dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity); Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. MET8 subfamily. (264 aa)
hem15Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (423 aa)
met1Probable uroporphyrinogen-III C-methyltransferase; Siroheme synthase involved in methionine biosynthesis. Belongs to the precorrin methyltransferase family. (496 aa)
cyc3Putative cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (377 aa)
SPCC417.11cUncharacterized aminotransferase C417.11c; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (438 aa)
hem2Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity). (329 aa)
hem4Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (251 aa)
hem3Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (336 aa)
hem14Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (490 aa)
ymc1Uncharacterized mitochondrial carrier C4G9.20c. (298 aa)
hem12Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (355 aa)
hem13Probable oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX (By similarity). (312 aa)
cox10Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. (387 aa)
shy1Cytochrome oxidase assembly protein shy1; Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane; Belongs to the SURF1 family. (290 aa)
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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