STRINGSTRING
rti1 rti1 dmc1 dmc1 rad55 rad55 rad57 rad57 swi5 swi5 sfr1 sfr1 rad51 rad51 rad52 rad52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rti1DNA repair and recombination protein rti1; Active in the repair of DNA damage and in mating-type switching. Probably involved in the repair of DNA double-strands breaks. Has a role in promoting S phase completion. (371 aa)
dmc1Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily. (332 aa)
rad55DNA repair protein rhp55; Required for radiation resistance and meiotic viability and acts in recombination and recombinational DNA repair pathways. (350 aa)
rad57DNA repair protein rhp57; Involved in recombination DNA repair and in the repair of gamma-ray-induced damage. (354 aa)
swi5Mating-type switching protein swi5; Required for normal mating-type switching. Also involved in the rhp51-dependent recombination DNA repair pathway. (85 aa)
sfr1Swi5-dependent recombination DNA repair protein 1; Involved in DNA recombination repair and meiotic chromosome segregation; Belongs to the SFR1/MEI5 family. (299 aa)
rad51DNA repair protein rhp51; Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments. Belongs to the RecA family. RAD51 subfamily. (365 aa)
rad52DNA repair and recombination protein rad22; Active in the repair of DNA damage and in mating-type switching. Probably involved in the repair of DNA double-strands breaks. Has a role in promoting S phase completion; Belongs to the RAD52 family. (469 aa)
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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