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arg4 arg4 SPAC1B3.01c SPAC1B3.01c cts1 cts1 dcd1 dcd1 ura6 ura6 SPCC965.14c SPCC965.14c urk1 urk1 ura5 ura5 ura4 ura4 ura3 ura3 tmp1 tmp1 cdc22 cdc22 suc22 suc22 ndk1 ndk1 ura1 ura1 uck2 uck2 dut1 dut1 urg2 urg2 ynd1 ynd1 yfh7 yfh7 ura2 ura2 hal3 hal3
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second shell of interactors
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arg4Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. (1160 aa)
SPAC1B3.01cUracil phosphoribosyltransferase 1; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (219 aa)
cts1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (600 aa)
dcd1Deoxycytidylate deaminase; Supplies the nucleotide substrate for thymidylate synthetase. Belongs to the cytidine and deoxycytidylate deaminase family. (322 aa)
ura6Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (191 aa)
SPCC965.14cProbable cytosine deaminase; Converts cytosine to uracil or 5-methylcytosine to thymine by deaminating carbon number 4; Belongs to the cytidine and deoxycytidylate deaminase family. (162 aa)
urk1Uridine kinase; Catalyzes the conversion of uridine into UMP and cytidine into CMP in the pyrimidine salvage pathway. (454 aa)
ura5Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily. (215 aa)
ura4Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (264 aa)
ura3Dihydroorotate dehydrogenase (quinone), mitochondrial; In the de novo pyrimidine biosynthesis pathway, catalyzes the stereospecific oxidation of (S)-dihydroorotate to orotate with reduction of flavin and the transfer of electrons to ubiquinone, which is part of the repiratory chain. Does not use fumarate and NAD as electron acceptors; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (443 aa)
tmp1Thymidylate kinase; Catalyzes the conversion of dTMP to dTDP. (210 aa)
cdc22Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (811 aa)
suc22Ribonucleoside-diphosphate reductase small chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (391 aa)
ndk1Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (151 aa)
ura1Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding three enzymatic activities of the pyrimidine pathway (GATase, CPSase, and ATCase). In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. (2244 aa)
uck2Uracil phosphoribosyltransferase 2; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (220 aa)
dut1Probable deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (140 aa)
urg2Putative uracil phosphoribosyltransferase urg2; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate; Belongs to the UPRTase family. (204 aa)
ynd1Golgi apyrase; Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates. Required for Golgi glycosylation and cell wall integrity. Involved in N-mannosylation of proteins in Golgi. (572 aa)
yfh7Putative uridine kinase C227.14. (235 aa)
ura2Probable dihydroorotase. (337 aa)
hal3Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily. (625 aa)
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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