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| | any2 | Uncharacterized protein C1F12.05. (377 aa) |
| | sec3 | Uncharacterized protein C17G8.12. (608 aa) |
| | arc5 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (152 aa) |
| | neo1 | Putative phospholipid-transporting ATPase C6C3.06c; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1033 aa) |
| | mug64 | Meiotically up-regulated gene 64 protein; Has a role in meiosis. (286 aa) |
| | pan1 | Actin cytoskeleton-regulatory complex protein pan1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (1794 aa) |
| | chc1 | Probable clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. (1666 aa) |
| | aly3 | Arrestin domain-containing protein C584.15c; Belongs to the arrestin family. (594 aa) |
| | SPAC23D3.13c | Protein MON2 homolog; Required for traffic between late Golgi and early endosomes. Required for endocytosis and maintenance of vacuolar structure (By similarity). (1616 aa) |
| | cdc15 | Cell division control protein 15; After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Appears to mediate cytoskeletal rearrangements required for cytokinesis. Essential for viability. (927 aa) |
| | bzz1 | Protein BZZ1; Plays a role in endocytosis and trafficking to the vacuole. Functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress (By similarity); Belongs to the BZZ1 family. (642 aa) |
| | rod1 | Arrestin domain-containing protein C31A2.12. (596 aa) |
| | apm4 | AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP50 is a subunit of the plasma membrane adaptor (Potential). (446 aa) |
| | cdc42 | Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily. (192 aa) |
| | sst4 | Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (610 aa) |
| | lsb5 | Protein lsb5; Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking; Belongs to the LSB5 family. (304 aa) |
| | ent3 | ENTH domain-containing protein C794.11c. (476 aa) |
| | arc1 | Actin-related protein 2/3 complex subunit 1; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (377 aa) |
| | pik3 | Phosphatidylinositol 3-kinase vps34; Phosphatidylinositol 3-kinase homolog required for vacuolar sorting and segregation; Belongs to the PI3/PI4-kinase family. (801 aa) |
| | hhp2 | Casein kinase I homolog hhp2; Involved in DNA repair. May regulate the activity of protein(s) involved in double strand break repair caused by gamma rays; Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. (400 aa) |
| | hhp1 | Casein kinase I homolog hhp1; Involved in DNA repair. Has a probable role in repairing alkylated DNA and may regulate the activity of protein(s) involved in double strand break repair caused by gamma rays; Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. (365 aa) |
| | cki2 | Casein kinase I homolog 2; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. May contribute to the regulation of morphology. (435 aa) |
| | cki1 | Casein kinase I homolog 1; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. (446 aa) |
| | ypt5 | GTP-binding protein ypt5; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (211 aa) |
| | irc6 | Uncharacterized protein C19A8.11c. (246 aa) |
| | osh3 | Oxysterol-binding protein homolog C23H4.01c. (945 aa) |
| | irs4 | Increased rDNA silencing protein 4 homolog; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity). (1379 aa) |
| | pil2 | Probable sphingolipid long chain base-responsive protein pil2; Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase ksg1/ppk21 activity and regulating their downstream CWI pathways pck2-MAP kinase pathway and protein kinase gad8 pathway. Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress (By similarity). (383 aa) |
| | arc2 | Actin-related protein 2/3 complex subunit 2; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). (317 aa) |
| | osh2 | Oxysterol-binding protein homolog C2F12.05c. (1310 aa) |
| | wsp1 | Wiskott-Aldrich syndrome protein homolog 1; Has a role in regulating actin assembly, so regulating polarized growth. (574 aa) |
| | sip1 | Pof6 interactor protein 1; Required for endocytosis. Also involved in cytokinesis and cell division. (1919 aa) |
| | apl1 | AP-2 complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Beta adaptin is a subunit of the plasma membrane adaptor (By similarity). (677 aa) |
| | syp1 | Cytoskeletal protein syp1; Multi-functional protein that contributes to the endocytic process, but also to events that occur at the neck during cytokinesis. Plays a role as an endocytic adapters with membrane-tubulation activity that associates with transmembrane cargo proteins and initiates the formation of endocytic sites. Contributes to the stabilization of the nascent clathrin-coated pit. Plays also a role in late endocytosis by mediating vesiculation. Involved in the regulation of cell cycle- dependent dynamics of the septin cytoskeleton by promoting septin turnover in different c [...] (818 aa) |
| | pal2 | Uncharacterized protein C6B1.03c. (272 aa) |
| | fim1 | Fimbrin; Binds to actin, and functionally associates with actin structures involved in the development and maintenance of cell polarity. Plays a role in cytokinesis. Plays important roles in mating and in spore formation. (614 aa) |
| | any1 | Uncharacterized protein C18H10.20c. (361 aa) |
| | rcr1 | Uncharacterized protein C19C7.05. (150 aa) |
| | yap18 | ENTH domain-containing protein C19F8.03c. (649 aa) |
| | cki3 | Casein kinase I homolog 3; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. (439 aa) |
| | ucp3 | UBA domain-containing protein 3. (601 aa) |
| | hob1 | Protein hob1; Has a role in DNA damage signaling as a part of stress response processes. (466 aa) |
| | SPBC32F12.07c | Uncharacterized RING finger protein C32F12.07c. (340 aa) |
| | ent1 | Epsin-1; Binds to membranes enriched in phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin. Belongs to the epsin family. (702 aa) |
| | erv29 | Surfeit locus protein 4 homolog; Belongs to the SURF4 family. (302 aa) |
| | SPBC19C2.10 | Uncharacterized protein C19C2.10. (501 aa) |
| | osh6 | Oxysterol-binding protein homolog C23B6.01c. (479 aa) |
| | mug170 | Meiotically up-regulated gene 170 protein; Has a role in meiosis; Belongs to the arrestin family. (426 aa) |
| | pal1 | Protein pal1; Involved in cellular morphogenesis and cell wall integrity. Important for the maintenance of a cylindrical cell shape. (425 aa) |
| | apl4 | AP-1 complex subunit gamma-1; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. The AP-1 complex interacts directly with clathrin (By similarity). (865 aa) |
| | SPAC824.09c | Uncharacterized protein C824.09c; GTPase-activating protein for the ADP ribosylation factor family. (320 aa) |
| | end3 | Actin cytoskeleton-regulatory complex protein end3; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (375 aa) |
| | clc1 | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. (229 aa) |
| | vps1 | Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (678 aa) |
| | arp3 | Actin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). May be involved in cytokinesis. (427 aa) |
| | act1 | Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (375 aa) |
| | meu14 | Meiotic expression up-regulated protein 14; Has a role in nuclear division during meiosis II where it stabilizes the proper segregation of the spindle pole bodies. Also has a role in the formation and extension of the forespore membrane. (335 aa) |
| | ucp8 | UBA domain-containing protein 8. (829 aa) |
| | apm3 | AP-3 complex subunit mu; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole (By similarity); Belongs to the adaptor complexes medium subunit family. (425 aa) |
| | ypt7 | GTP-binding protein ypt7; Needed for homotypic vacuole fusion, the last step in the vacuole inheritance process; Belongs to the small GTPase superfamily. Rab family. (205 aa) |
| | mug137 | Meiotically up-regulated gene 137 protein; Has a role in meiosis and sporulation. (420 aa) |
| | ypp1 | Putative cargo-transport protein ypp1; Involved in endocytosis; Belongs to the YPP1 family. (862 aa) |
| | pil1 | Probable sphingolipid long chain base-responsive protein pil1; Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase ksg1/ppk21 activity and regulating their downstream CWI pathways pck2-MAP kinase pathway and protein kinase gad8 pathway. Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress (By similarity). (351 aa) |
| | pof6 | F-box protein pof6; Together with skp1, essential for septum processing and cell separation. (872 aa) |
| | aly2 | Putative arrestin-related trafficking adapter C2D10.04; May regulate endocytosis in response to extracellular stimuli; Belongs to the ALY1 family. (658 aa) |
| | dip1 | Protein dip1; May be involved in protein-linked oligosaccharide phosphorylation; Belongs to the LDB17 family. (374 aa) |
| | sec8 | Exocyst complex component sec8; Component of the exocyst complex involved in the delivery of secretory vesicles to the plasma membrane. Also required for polarized cell growth and division septum assembly. The exocyst complex plays an important role in the targeting of rho3, as well as the two main hydrolases required for cell separation, eng1 and agn1, to the cell wall surrounding the septum before cell separation begins. (1073 aa) |
| | ync13 | Uncharacterized protein C11E3.02c. (1237 aa) |
| | shd1 | Actin cytoskeleton-regulatory complex protein sla1; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). (1420 aa) |
| | ucp7 | UBA domain-containing protein 7. (697 aa) |
| | SPBC17A3.03c | Probable tyrosine-protein phosphatase C17A3.03c; Belongs to the protein-tyrosine phosphatase family. (287 aa) |
| | arp2 | Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). During cytokinesis it colocalizes to the cortical actin patches until spetation is complete. Has a role in the mobility of these patches. Essential for viability. (390 aa) |
| | hob3 | Protein hob3; Involved in cytokinesis and septation where it has a role in the localization of F-actin. (264 aa) |
| | myo1 | Myosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Contributes to proper septation by transporting vesicles containing septal material to the division site and is involved in the formation of sterol-rich membrane domains at the cell division site. Required also for mating. (1217 aa) |
| | arc3 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (174 aa) |
| | aps2 | AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). (143 aa) |
| | lsb4 | SH3 domain-containing protein PJ696.02; Belongs to the SH3YL1 family. (430 aa) |
| | ubp9 | Probable ubiquitin carboxyl-terminal hydrolase 9; Ubiquitin C-terminal hydrolase involved in regulating actin dynamics and/or endocytosis at cell tips and septa. Belongs to the peptidase C19 family. (585 aa) |
| | nbr1 | ZZ-type zinc finger-containing protein P35G2.11c. (397 aa) |
| | vrp1 | Verprolin; Involved in cytoskeletal organization and cellular growth. May exert its effects on the cytoskeleton directly, or indirectly via proline-binding proteins such as profilin or proteins possessing SH3 domains. Plays a role in actin patch assembly by enhancing the ability of myo1 to stimulate actin polymerization by the Arp2/3 complex. (309 aa) |
| | end4 | Endocytosis protein end4; Required for cellular morphogenesis and polarization of the cortical cytoskeleton. Required for establishment of new polarized growth zones where it acts in actin organization. Involved plasma membrane internalization and is essential for fluid-phase endocytosis. Belongs to the SLA2 family. (1102 aa) |
| | ede1 | Uncharacterized calcium-binding protein C800.10c. (1116 aa) |
| | ypt71 | GTP-binding protein ypt71. (208 aa) |
| | apl3 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adaptor (By similarity). (878 aa) |
| | arc4 | Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). (168 aa) |
| | shu1 | Uncharacterized GPI-anchored protein C1F8.02c. (226 aa) |
| | aly1 | Putative arrestin-related trafficking adapter SPBC839.02; May regulate endocytosis in response to extracellular stimuli. (504 aa) |
| | sst6 | ESCRT-I complex subunit vps23; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex (By similarity). (487 aa) |
| | svp26 | Protein svp26; May play a role in retention of a subset of membrane proteins in the early Golgi compartments; Belongs to the SVP26 family. (227 aa) |
