10 items (Schizosaccharomyces pombe) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	hal3	Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily. (625 aa)
	cts1	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (600 aa)
	urk1	Uridine kinase; Catalyzes the conversion of uridine into UMP and cytidine into CMP in the pyrimidine salvage pathway. (454 aa)
	arg4	Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. (1160 aa)
	tmp1	Thymidylate kinase; Catalyzes the conversion of dTMP to dTDP. (210 aa)
	cdc22	Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (811 aa)
	suc22	Ribonucleoside-diphosphate reductase small chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (391 aa)
	ndk1	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (151 aa)
	ura1	Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding three enzymatic activities of the pyrimidine pathway (GATase, CPSase, and ATCase). In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. (2244 aa)
	yfh7	Putative uridine kinase C227.14. (235 aa)

Your Current Organism:

Schizosaccharomyces pombe

NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
arg4	cts1	O94313	O42644	Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.474
arg4	ura1	O94313	Q09794	Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family.	Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding three enzymatic activities of the pyrimidine pathway (GATase, CPSase, and ATCase). In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.	0.916
cdc22	cts1	P36602	O42644	Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.613
cdc22	hal3	P36602	Q9UTI7	Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily.	0.935
cdc22	ndk1	P36602	P49740	Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.983
cdc22	suc22	P36602	P36603	Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Ribonucleoside-diphosphate reductase small chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	0.999
cdc22	tmp1	P36602	P36590	Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Thymidylate kinase; Catalyzes the conversion of dTMP to dTDP.	0.984
cts1	arg4	O42644	O94313	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family.	0.474
cts1	cdc22	O42644	P36602	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.613
cts1	hal3	O42644	Q9UTI7	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily.	0.729
cts1	ndk1	O42644	P49740	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.985
cts1	tmp1	O42644	P36590	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Thymidylate kinase; Catalyzes the conversion of dTMP to dTDP.	0.586
cts1	ura1	O42644	Q09794	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding three enzymatic activities of the pyrimidine pathway (GATase, CPSase, and ATCase). In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.	0.710
hal3	cdc22	Q9UTI7	P36602	Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily.	Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.935
hal3	cts1	Q9UTI7	O42644	Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.729
hal3	ndk1	Q9UTI7	P49740	Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.730
hal3	suc22	Q9UTI7	P36603	Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily.	Ribonucleoside-diphosphate reductase small chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	0.615
hal3	tmp1	Q9UTI7	P36590	Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily.	Thymidylate kinase; Catalyzes the conversion of dTMP to dTDP.	0.994
hal3	yfh7	Q9UTI7	Q9UTC5	Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily.	Putative uridine kinase C227.14.	0.729
ndk1	cdc22	P49740	P36602	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.983