node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SPAC1B3.01c | ura4 | O13867 | P14965 | Uracil phosphoribosyltransferase 1; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. | 0.954 |
SPAC1B3.01c | ura6 | O13867 | O59771 | Uracil phosphoribosyltransferase 1; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.932 |
arg4 | arg5 | O94313 | O60060 | Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | 0.998 |
arg4 | cts1 | O94313 | O42644 | Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.474 |
arg4 | ura1 | O94313 | Q09794 | Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. | Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding three enzymatic activities of the pyrimidine pathway (GATase, CPSase, and ATCase). In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. | 0.916 |
arg4 | ura2 | O94313 | Q9UTI0 | Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. | Probable dihydroorotase. | 0.756 |
arg4 | ura3 | O94313 | P32747 | Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; In the de novo pyrimidine biosynthesis pathway, catalyzes the stereospecific oxidation of (S)-dihydroorotate to orotate with reduction of flavin and the transfer of electrons to ubiquinone, which is part of the repiratory chain. Does not use fumarate and NAD as electron acceptors; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.978 |
arg4 | ura4 | O94313 | P14965 | Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. | 0.708 |
arg4 | ura5 | O94313 | O94331 | Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily. | 0.639 |
arg5 | arg4 | O60060 | O94313 | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. | 0.998 |
arg5 | cts1 | O60060 | O42644 | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.418 |
arg5 | ura1 | O60060 | Q09794 | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding three enzymatic activities of the pyrimidine pathway (GATase, CPSase, and ATCase). In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. | 0.952 |
arg5 | ura2 | O60060 | Q9UTI0 | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | Probable dihydroorotase. | 0.757 |
arg5 | ura3 | O60060 | P32747 | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; In the de novo pyrimidine biosynthesis pathway, catalyzes the stereospecific oxidation of (S)-dihydroorotate to orotate with reduction of flavin and the transfer of electrons to ubiquinone, which is part of the repiratory chain. Does not use fumarate and NAD as electron acceptors; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.899 |
arg5 | ura4 | O60060 | P14965 | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. | 0.639 |
arg5 | ura5 | O60060 | O94331 | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP); Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily. | 0.745 |
cts1 | arg4 | O42644 | O94313 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Carbamoyl-phosphate synthase arginine-specific large chain; Belongs to the CarB family. | 0.474 |
cts1 | arg5 | O42644 | O60060 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Carbamoyl-phosphate synthase arginine-specific small chain; Belongs to the CarA family. | 0.418 |
cts1 | ura1 | O42644 | Q09794 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding three enzymatic activities of the pyrimidine pathway (GATase, CPSase, and ATCase). In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. | 0.710 |
cts1 | ura2 | O42644 | Q9UTI0 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Probable dihydroorotase. | 0.497 |