8 items (Schizosaccharomyces pombe) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rad55	DNA repair protein rhp55; Required for radiation resistance and meiotic viability and acts in recombination and recombinational DNA repair pathways. (350 aa)
	swi5	Mating-type switching protein swi5; Required for normal mating-type switching. Also involved in the rhp51-dependent recombination DNA repair pathway. (85 aa)
	rad57	DNA repair protein rhp57; Involved in recombination DNA repair and in the repair of gamma-ray-induced damage. (354 aa)
	sfr1	Swi5-dependent recombination DNA repair protein 1; Involved in DNA recombination repair and meiotic chromosome segregation; Belongs to the SFR1/MEI5 family. (299 aa)
	dmc1	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily. (332 aa)
	rad51	DNA repair protein rhp51; Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments. Belongs to the RecA family. RAD51 subfamily. (365 aa)
	mcp7	Meiotic coiled-coil protein 7; Required for meiotic recombination. (210 aa)
	meu13	Homologous-pairing protein 2; Required for proper homologous pairing and efficient cross- over and intragenic recombination during meiosis. Acts indirectly in a process facilitating homologous recombination. Acts during mid- to late-horse-tail period. (216 aa)

Your Current Organism:

Schizosaccharomyces pombe

NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dmc1	mcp7	O42634	Q09739	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily.	Meiotic coiled-coil protein 7; Required for meiotic recombination.	0.892
dmc1	meu13	O42634	Q9HGK2	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily.	Homologous-pairing protein 2; Required for proper homologous pairing and efficient cross- over and intragenic recombination during meiosis. Acts indirectly in a process facilitating homologous recombination. Acts during mid- to late-horse-tail period.	0.933
dmc1	rad51	O42634	P36601	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily.	DNA repair protein rhp51; Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments. Belongs to the RecA family. RAD51 subfamily.	0.925
dmc1	rad55	O42634	O14129	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily.	DNA repair protein rhp55; Required for radiation resistance and meiotic viability and acts in recombination and recombinational DNA repair pathways.	0.916
dmc1	rad57	O42634	Q9UUL2	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily.	DNA repair protein rhp57; Involved in recombination DNA repair and in the repair of gamma-ray-induced damage.	0.977
dmc1	sfr1	O42634	Q9USV1	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily.	Swi5-dependent recombination DNA repair protein 1; Involved in DNA recombination repair and meiotic chromosome segregation; Belongs to the SFR1/MEI5 family.	0.887
dmc1	swi5	O42634	Q9UUB7	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily.	Mating-type switching protein swi5; Required for normal mating-type switching. Also involved in the rhp51-dependent recombination DNA repair pathway.	0.816
mcp7	dmc1	Q09739	O42634	Meiotic coiled-coil protein 7; Required for meiotic recombination.	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily.	0.892
mcp7	meu13	Q09739	Q9HGK2	Meiotic coiled-coil protein 7; Required for meiotic recombination.	Homologous-pairing protein 2; Required for proper homologous pairing and efficient cross- over and intragenic recombination during meiosis. Acts indirectly in a process facilitating homologous recombination. Acts during mid- to late-horse-tail period.	0.999
mcp7	rad51	Q09739	P36601	Meiotic coiled-coil protein 7; Required for meiotic recombination.	DNA repair protein rhp51; Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments. Belongs to the RecA family. RAD51 subfamily.	0.826
mcp7	rad57	Q09739	Q9UUL2	Meiotic coiled-coil protein 7; Required for meiotic recombination.	DNA repair protein rhp57; Involved in recombination DNA repair and in the repair of gamma-ray-induced damage.	0.527
mcp7	swi5	Q09739	Q9UUB7	Meiotic coiled-coil protein 7; Required for meiotic recombination.	Mating-type switching protein swi5; Required for normal mating-type switching. Also involved in the rhp51-dependent recombination DNA repair pathway.	0.548
meu13	dmc1	Q9HGK2	O42634	Homologous-pairing protein 2; Required for proper homologous pairing and efficient cross- over and intragenic recombination during meiosis. Acts indirectly in a process facilitating homologous recombination. Acts during mid- to late-horse-tail period.	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily.	0.933
meu13	mcp7	Q9HGK2	Q09739	Homologous-pairing protein 2; Required for proper homologous pairing and efficient cross- over and intragenic recombination during meiosis. Acts indirectly in a process facilitating homologous recombination. Acts during mid- to late-horse-tail period.	Meiotic coiled-coil protein 7; Required for meiotic recombination.	0.999
meu13	rad51	Q9HGK2	P36601	Homologous-pairing protein 2; Required for proper homologous pairing and efficient cross- over and intragenic recombination during meiosis. Acts indirectly in a process facilitating homologous recombination. Acts during mid- to late-horse-tail period.	DNA repair protein rhp51; Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments. Belongs to the RecA family. RAD51 subfamily.	0.738
meu13	rad55	Q9HGK2	O14129	Homologous-pairing protein 2; Required for proper homologous pairing and efficient cross- over and intragenic recombination during meiosis. Acts indirectly in a process facilitating homologous recombination. Acts during mid- to late-horse-tail period.	DNA repair protein rhp55; Required for radiation resistance and meiotic viability and acts in recombination and recombinational DNA repair pathways.	0.431
rad51	dmc1	P36601	O42634	DNA repair protein rhp51; Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments. Belongs to the RecA family. RAD51 subfamily.	Meiotic recombination protein dmc1; Required for meiotic recombination and cell cycle progression. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical and stacked ring nucleoprotein filaments. Belongs to the RecA family. DMC1 subfamily.	0.925
rad51	mcp7	P36601	Q09739	DNA repair protein rhp51; Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments. Belongs to the RecA family. RAD51 subfamily.	Meiotic coiled-coil protein 7; Required for meiotic recombination.	0.826
rad51	meu13	P36601	Q9HGK2	DNA repair protein rhp51; Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments. Belongs to the RecA family. RAD51 subfamily.	Homologous-pairing protein 2; Required for proper homologous pairing and efficient cross- over and intragenic recombination during meiosis. Acts indirectly in a process facilitating homologous recombination. Acts during mid- to late-horse-tail period.	0.738
rad51	rad55	P36601	O14129	DNA repair protein rhp51; Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments. Belongs to the RecA family. RAD51 subfamily.	DNA repair protein rhp55; Required for radiation resistance and meiotic viability and acts in recombination and recombinational DNA repair pathways.	0.963