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psu1 psu1 asl1 asl1 pho4 pho4 tdh1 tdh1 isp3 isp3 plb4 plb4 pho1 pho1 knh2 knh2 aah1 aah1 meu10 meu10 map4 map4 yps1 yps1 psu2 psu2 mug56 mug56 bgl2 bgl2 ecm33 ecm33 plb3 plb3 cda1 cda1 gas5 gas5 mde10 mde10 aah3 aah3 plb5 plb5 mok14 mok14 mok12 mok12 plb2 plb2 crr1 crr1 gas2 gas2 ags1 ags1 SPBP23A10.11c SPBP23A10.11c gas1 gas1 mam3 mam3 cts2 cts2 bgs1 bgs1 knh1 knh1 eng2 eng2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
psu1Probable secreted beta-glucosidase PSU1; Involved in cell wall synthesis. May be required for the activation of 1,3-beta-glucan synthase; Belongs to the SUN family. (417 aa)
asl1Alkali-sensitive linkage protein 1. (530 aa)
pho4Thiamine-repressible acid phosphatase pho4; May dephosphorylate thiamine phosphates; Belongs to the histidine acid phosphatase family. (463 aa)
tdh1Glyceraldehyde-3-phosphate dehydrogenase 1; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
isp3Sexual differentiation process protein isp3. (182 aa)
plb4Putative lysophospholipase SPAC977.09c; Catalyzes the release of fatty acids from lysophospholipids. (673 aa)
pho1Acid phosphatase. (453 aa)
knh2UPF0619 GPI-anchored membrane protein C1322.10. (262 aa)
aah1Alpha-amylase 1. (625 aa)
meu10Meiotic expression up-regulated protein 10; Required for the formation of the mature spore wall, where it is needed to ensure correct localization of 1,3-beta-glucan. (416 aa)
map4P cell-type agglutination protein map4; P cell-type specific protein which involved in agglutination during conjugation. (948 aa)
yps1Aspartic proteinase yapsin-1; Cleaves at paired basic residues. Belongs to the peptidase A1 family. (521 aa)
psu2Probable secreted beta-glucosidase C2G2.17c; Cell surface beta-glucosidase involved in cell wall biogenesis; Belongs to the SUN family. (319 aa)
mug56Meiotically up-regulated gene 56 protein; Has a role in meiosis. (965 aa)
bgl2Glucan 1,3-beta-glucosidase; Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase. (321 aa)
ecm33Cell wall protein ecm33; Involved in the negative feedback regulation of pmk1 cell integrity signaling and is linked to cellular calcium signaling. (421 aa)
plb3Putative lysophospholipase SPAC1A6.03c; Catalyzes the release of fatty acids from lysophospholipids. Belongs to the lysophospholipase family. (662 aa)
cda1Chitin deacetylase 1; Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin. Required for proper spore formation. Belongs to the polysaccharide deacetylase family. (320 aa)
gas51,3-beta-glucanosyltransferase gas5; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. (510 aa)
mde10Zinc metalloprotease mde10; Has a role in the development of the spore envelope. (512 aa)
aah3Alpha-amylase 3; Has a role in cell wall biosynthesis where it is involved in maintaining cell wall strength and shape. (564 aa)
plb5Putative lysophospholipase C1450.09c; Catalyzes the release of fatty acids from lysophospholipids. (623 aa)
mok14Cell wall alpha-1,3-glucan synthase mok14. (1369 aa)
mok12Cell wall alpha-1,3-glucan synthase mok12. (2352 aa)
plb2Probable lysophospholipase C1786.02; Catalyzes the release of fatty acids from lysophospholipids. (644 aa)
crr1Probable glycosidase C21B10.07. (419 aa)
gas21,3-beta-glucanosyltransferase gas2; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall; Belongs to the glycosyl hydrolase 72 family. (459 aa)
ags1Cell wall alpha-1,3-glucan synthase ags1; Required for alpha-1,3-glucan and alpha-1,4-glucan production which are required for cell wall synthesis. (2410 aa)
SPBP23A10.11cUncharacterized serine-rich protein P23A10.11c. (507 aa)
gas11,3-beta-glucanosyltransferase gas1; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. (542 aa)
mam3M cell-type agglutination protein mam3; M cell-type specific protein involved in agglutination during conjugation; Belongs to the mam3/map4 family. (1082 aa)
cts2Chitinase-like protein PB1E7.04c. (1236 aa)
bgs11,3-beta-glucan synthase component bgs1; Required for the assembly of the division septum and maintenance of cell polarity. (1729 aa)
knh1Uncharacterized protein C11C11.05. (284 aa)
eng2Putative endo-1,3(4)-beta-glucanase 2; Belongs to the glycosyl hydrolase 81 family. (706 aa)
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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