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| | mrpl3 | 54S ribosomal protein L3, mitochondrial; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL44 subfamily. (326 aa) |
| | mrpl16 | 54S ribosomal protein L16, mitochondrial. (215 aa) |
| | mrp15 | 54S ribosomal protein L15, mitochondrial; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL57 subfamily. (210 aa) |
| | mrpl37 | 54S ribosomal protein L37, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL54 family. (139 aa) |
| | SPCC63.03 | Uncharacterized J domain-containing protein C63.03. (612 aa) |
| | rml2 | 54S ribosomal protein rml2, mitochondrial; Belongs to the universal ribosomal protein uL2 family. (362 aa) |
| | mrpl10 | 54S ribosomal protein L10, mitochondrial; Belongs to the universal ribosomal protein uL15 family. (254 aa) |
| | mrpl25 | 54S ribosomal protein L25, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL59 family. (145 aa) |
| | mdm34 | Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. (452 aa) |
| | mrpl51 | 54S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL43 family. (145 aa) |
| | mrps17 | 37S ribosomal protein S17, mitochondrial; Belongs to the universal ribosomal protein uS17 family. (90 aa) |
| | mtx1 | Metaxin-like protein C409.19c; May be involved in transport of proteins into the mitochondrion; Belongs to the metaxin family. (450 aa) |
| | cox1101 | Cytochrome c oxidase assembly protein cox11-1; Rsm22-1 is involved in mitochondrion-encoded protein synthesis; In the C-terminal section; belongs to the COX11/CtaG family. (753 aa) |
| | mrpl19 | 54S ribosomal protein L19, mitochondrial; Belongs to the universal ribosomal protein uL11 family. (144 aa) |
| | sdh1 | Probable succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (641 aa) |
| | mim1 | Mitochondrial import protein 1; Required for the assembly of the TOM (translocase of outer membrane) receptor complex, which is responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins; Belongs to the MIM1 family. (71 aa) |
| | tim16 | Mitochondrial import inner membrane translocase subunit tim16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (ssc1) via its interaction with PAM18/TIM14. May act by positioning pam18/tim14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. (128 aa) |
| | mdm12 | Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pat [...] (273 aa) |
| | mrp21 | 37S ribosomal protein mrp21, mitochondrial; Belongs to the bacterial ribosomal protein bS21 family. (121 aa) |
| | cox1102 | Cytochrome c oxidase assembly protein cox11-2; Rsm22-2 is involved in mitochondrion-encoded protein synthesis; In the C-terminal section; belongs to the COX11/CtaG family. (753 aa) |
| | mrpl27 | 54S ribosomal protein L27, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL41 family. (93 aa) |
| | pog1 | DNA polymerase gamma; Involved in the replication of mitochondrial DNA. (1018 aa) |
| | pda1 | Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (409 aa) |
| | tim13 | Mitochondrial import inner membrane translocase subunit tim13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (95 aa) |
| | sam50 | SAM50-like protein SPAC17C9.06; May be required for the assembly pathway of mitochondrial outer membrane proteins; Belongs to the SAM50/omp85 family. (475 aa) |
| | mrp5 | Probable 37S ribosomal protein S5, mitochondrial. (387 aa) |
| | img2 | 54S ribosomal protein img2, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL49 family. (105 aa) |
| | mrpl6 | Putative 54S ribosomal protein L6, mitochondrial. (213 aa) |
| | tim8 | Mitochondrial import inner membrane translocase subunit tim8; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex is non essential and only mediates [...] (98 aa) |
| | atp20 | ATP synthase subunit g, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (118 aa) |
| | tim15 | Uncharacterized protein C24H6.02c. (175 aa) |
| | mrp20 | 54S ribosomal protein L23, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (161 aa) |
| | mrp11 | 54S ribosomal protein L11, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (216 aa) |
| | rsm24 | 37S ribosomal protein S24, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (258 aa) |
| | pdb1 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (366 aa) |
| | rip1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical g [...] (228 aa) |
| | atp15 | Putative ATP synthase subunit epsilon, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechan [...] (67 aa) |
| | mrpl4 | 54S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL29 family. (144 aa) |
| | mic19 | MICOS complex subunit mic19; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (162 aa) |
| | tim22 | Mitochondrial import inner membrane translocase subunit tim22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (175 aa) |
| | mgr2 | Protein mgr2; Required for cell viability in cells lacking mitochondrial DNA; Belongs to the MGR2 family. (120 aa) |
| | cox4 | Cytochrome c oxidase subunit 4, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (164 aa) |
| | qcr2 | Cytochrome b-c1 complex subunit 2, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradie [...] (426 aa) |
| | mrpl44 | 54S ribosomal protein L44, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (100 aa) |
| | atp1 | ATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (536 aa) |
| | ssc1 | Heat shock 70 kDa protein, mitochondrial; Belongs to the heat shock protein 70 family. (674 aa) |
| | atp2 | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (525 aa) |
| | sdh2 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (275 aa) |
| | var1 | Ribosomal protein var1, mitochondrial; Essential for mitochondrial protein synthesis and required for the maturation of small ribosomal subunits. (227 aa) |
| | atp9 | ATP synthase subunit 9, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (74 aa) |
| | atp8 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (48 aa) |
| | atp6 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (257 aa) |
| | cox2 | Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (248 aa) |
| | cox3 | Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (269 aa) |
| | ina17 | Inner membrane assembly complex subunit 17; Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase. INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain. (112 aa) |
| | tom6 | Uncharacterized protein SPAC823.17. (48 aa) |
| | cox1 | Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (537 aa) |
| | cob1 | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (387 aa) |
| | mas2 | Probable mitochondrial-processing peptidase subunit alpha; Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. (502 aa) |
| | mrpl20 | 54S ribosomal protein L20, mitochondrial. (197 aa) |
| | pdx1 | Probable pyruvate dehydrogenase protein X component, mitochondrial; Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex (By similarity). (456 aa) |
| | cox9 | Cytochrome c oxidase subunit 9, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (58 aa) |
| | rtc6 | 54S ribosomal protein c83.06c, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. (92 aa) |
| | kgd2 | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (452 aa) |
| | tim54 | Mitochondrial import inner membrane translocase subunit tim54; Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as external driving force (By similarity). (347 aa) |
| | cox12 | Cytochrome c oxidase subunit 12, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (86 aa) |
| | mic26 | Uncharacterized protein C1442.05c. (177 aa) |
| | pam17 | Presequence translocated-associated motor subunit pam17, mitochondrial; Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. (209 aa) |
| | rpm2 | ATP-dependent RNA helicase suv3, mitochondrial; Required for intron-independent turnover and processing of mitochondrial RNA. It is a key control element in nuclear-mitochondrial interactions (By similarity). (647 aa) |
| | mrpl17 | 54S ribosomal protein L17, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL46 family. (268 aa) |
| | atp7 | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (175 aa) |
| | mrpl32 | Probable 54S ribosomal protein L32, mitochondrial; Component of the large subunit of mitochondrial ribosome. Belongs to the bacterial ribosomal protein bL32 family. (103 aa) |
| | atp17 | ATP synthase subunit f, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (96 aa) |
| | atp4 | ATP synthase subunit 4, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (244 aa) |
| | mrpl8 | 54S ribosomal protein L8, mitochondrial; Belongs to the bacterial ribosomal protein bL17 family. (207 aa) |
| | mrpl38 | 54S ribosomal protein L38, mitochondrial. (136 aa) |
| | cox5 | Cytochrome c oxidase polypeptide 5, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembr [...] (186 aa) |
| | vms1 | VMS1 homolog C1827.04; Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Component of an evolutionarily conserved system for ubiquitin-mediated mitochondria-associated protein degradation (MAD), which is necessary to maintain mitochondrial, cellular, and organismal viability (By similarity); Belongs to the ANKZF1/VMS1 family. (600 aa) |
| | fyv4 | Protein fyv4, mitochondrial; Involved in telomere length regulation; Belongs to the mitochondrion-specific ribosomal protein mS41 family. (113 aa) |
| | mrps8 | 37S ribosomal protein subunit S8, mitochondrial; Belongs to the universal ribosomal protein uS8 family. (152 aa) |
| | sdh3 | Succinate dehydrogenase cytochrome B subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (180 aa) |
| | snr1 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has an indirect role in endocytic membrane trafficking. May have a function in protein biosynthesis in mitochondrial small ribosomal subunit (By similarity). (429 aa) |
| | yml6 | 54S ribosomal protein yml6, mitochondrial; Belongs to the universal ribosomal protein uL4 family. (261 aa) |
| | mmp1 | Mitochondrial inner membrane protease subunit 1; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. (157 aa) |
| | atp3 | ATP synthase subunit gamma, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (301 aa) |
| | qcr7 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inn [...] (137 aa) |
| | atp5 | ATP synthase subunit 5, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (216 aa) |
| | cox13 | Cytochrome c oxidase subunit 13, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (130 aa) |
| | mrpl22 | 54S ribosomal protein L22, mitochondrial. (249 aa) |
| | qcr9 | Cytochrome b-c1 complex subunit 9; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inn [...] (67 aa) |
| | mrpl39 | 54S ribosomal protein L39, mitochondrial. (55 aa) |
| | SPBC3H7.04 | Putative 37S ribosomal protein S26B, mitochondrial. (220 aa) |
| | kgd1 | 2-oxoglutarate dehydrogenase, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (1009 aa) |
| | mmm1 | Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 su [...] (313 aa) |
| | rsm10 | 37S ribosomal protein S10, mitochondrial; Involved in mitochondrial genome encoded proteins translation. Involved in the binding of tRNA to the ribosomes (By similarity). (228 aa) |
| | mhr1 | Uncharacterized protein C18H10.17c. (175 aa) |
| | mrpl23 | 54S ribosomal protein L23, mitochondrial; Belongs to the universal ribosomal protein uL13 family. (157 aa) |
| | bot1 | 37S ribosomal protein S35, mitochondrial; Required for mitochondrial protein synthesis. Has a role in mitochondrial integrity and cell respiration. (315 aa) |
| | mrpl24 | 54S ribosomal protein L24, mitochondrial. (176 aa) |
| | tim44 | Mitochondrial import inner membrane translocase subunit tim44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 and its co-chaperone (mge1) to drive protein translocation into the matrix using ATP as an energy source. (427 aa) |
| | nam9 | 37S ribosomal protein S4-like, mitochondrial. (327 aa) |
| | mrpl33 | Probable 54S ribosomal protein L33, mitochondrial. (97 aa) |
| | yme1 | ATP-dependent zinc metalloprotease YME1 homolog; Putative ATP-dependent protease; In the C-terminal section; belongs to the peptidase M41 family. (709 aa) |
| | lat1 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (483 aa) |
| | gem1 | Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. (630 aa) |
| | sws2 | 37S ribosomal protein subunit sws2, mitochondrial; Belongs to the universal ribosomal protein uS13 family. (151 aa) |
| | mic60 | MICOS complex subunit mic60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity). (550 aa) |
| | cyt1 | Cytochrome c1, heme protein, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient ove [...] (307 aa) |
| | rsm23 | 37S ribosomal protein S23, mitochondrial; Required for maintenance of mitochondrial DNA. (476 aa) |
| | atp14 | ATP synthase subunit H, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (103 aa) |
| | mge1 | GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of ssc1 to substrate proteins (By similarity). (223 aa) |
| | mrps16 | Probable 37S ribosomal protein S16, mitochondrial. (96 aa) |
| | mug178 | Meiotically up-regulated gene 178 protein; Has a role in meiosis. (225 aa) |
| | tom7 | Mitochondrial import receptor subunit tom7; Belongs to the Tom7 family. (52 aa) |
| | qcr6 | Cytochrome b-c1 complex subunit 6; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inn [...] (214 aa) |
| | SPBC16A3.14 | Putative 37S ribosomal protein S26A, mitochondrial. (268 aa) |
| | rsm25 | 37S ribosomal protein S25, mitochondrial. (220 aa) |
| | mrp2 | Probable 37S ribosomal protein mrp2, mitochondrial. (105 aa) |
| | mrp51 | 37S ribosomal protein mrp51, mitochondrial. (303 aa) |
| | rsm27 | 37S ribosomal protein S27, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (93 aa) |
| | mrpl35 | 54S ribosomal protein L35, mitochondrial; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily. (308 aa) |
| | mrpl7 | Probable 54S ribosomal protein L7, mitochondrial. (287 aa) |
| | tom20 | Mitochondrial import receptor subunit tom20; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore (By similarity). (152 aa) |
| | tom70 | Probable mitochondrial import receptor subunit tom70; Receptor that accelerates the import of all mitochondrial precursor proteins. (625 aa) |
| | mrps12 | Probable 37S ribosomal protein S12, mitochondrial. (162 aa) |
| | mrpl28 | 54S ribosomal protein L28, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (118 aa) |
| | mrpl40 | 54S ribosomal protein L40, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (279 aa) |
| | mrps9 | 37S ribosomal protein S9, mitochondrial. (271 aa) |
| | rpo41 | DNA-directed RNA polymerase, mitochondrial; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Combines in the mitochondrion with mitochondrial transcription factor mtf1 as a holoenzyme to recognize and initiate transcription at the core mitochondrial promoters. (1154 aa) |
| | mrp10 | 37S ribosomal protein mrp10, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (88 aa) |
| | mrp4 | 37S ribosomal protein mrp4, mitochondrial; Belongs to the universal ribosomal protein uS2 family. (263 aa) |
| | atp18 | ATP synthase subunit J, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (60 aa) |
| | mrps18 | Putative 37S ribosomal protein S18, mitochondrial; Belongs to the universal ribosomal protein uS11 family. (223 aa) |
| | mdm10 | Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the recepto [...] (370 aa) |
| | tom22 | Mitochondrial import receptor subunit tom22; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom20 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore. Docks tom20 and tom70 for interaction with the general tom40 import pore (GIP) complex. May regulate the TOM machinery organization, stability and channel gating (By similarity). (144 aa) |
| | rsm7 | 37S ribosomal protein S7, mitochondrial. (259 aa) |
| | tom40 | Probable mitochondrial import receptor subunit tom40; Channel-forming protein essential for import of protein precursors into mitochondria. (344 aa) |
| | mrps28 | Probable 37S ribosomal protein S28, mitochondrial; Essential component of the small mitochondrial ribosomal subunit; Belongs to the universal ribosomal protein uS15 family. (288 aa) |
| | dld1 | Dihydrolipoyl dehydrogenase, mitochondrial; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes (By similarity). Malfunction of this protein blocks the progression of cell cycle from G1 to S phase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (511 aa) |
| | tam9 | 54S ribosomal protein L36, mitochondrial. (86 aa) |
| | tom5 | Mitochondrial import receptor subunit tom5; Component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. (49 aa) |
| | cox7 | Cytochrome c oxidase subunit 7; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (59 aa) |
| | kgd4 | 37S ribosomal protein YMR-31, mitochondrial. (89 aa) |
| | new15 | Putative mitochondrial ribosomal protein new15, mitochondrial. (86 aa) |
| | mim2 | Mitochondrial import protein 2; Component of the MIM complex required for outer membrane protein import (By similarity). Involved in import of the subset of proteins with multiple alpha-helical transmembrane segments (By similarity). (72 aa) |
| | mrp49 | Probable 54S ribosomal protein MRP49, mitochondrial; Involved in mitochondrial translation. (135 aa) |
| | atp19 | ATP synthase subunit K, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (68 aa) |
| | cox6 | Cytochrome c oxidase subunit 6, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (140 aa) |
| | tim10 | Mitochondrial import inner membrane translocase subunit tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (89 aa) |
| | img1 | 54S ribosomal protein subunit img1, mitochondrial. (182 aa) |
| | mrp17 | 37S ribosomal protein MRP17, mitochondrial; Belongs to the bacterial ribosomal protein bS6 family. (111 aa) |
| | tim14 | Mitochondrial import inner membrane translocase subunit tim14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (ssc1) (By similarity); Belongs to the TIM14 family. (140 aa) |
| | mmp2 | Mitochondrial inner membrane protease subunit 2; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. (180 aa) |
| | rsm18 | 37S ribosomal protein rsm18, mitochondrial; Belongs to the bacterial ribosomal protein bS18 family. (166 aa) |
| | mrpl12 | 54S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. (173 aa) |
| | mtf1 | Mitochondrial transcription factor 1; Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (366 aa) |
| | rsm19 | Probable ribosomal protein S19, mitochondrial. (93 aa) |
| | tim11 | ATP synthase subunit e, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (92 aa) |
| | mrpl31 | 54S ribosomal protein L31, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL60 family. (115 aa) |
| | SPCC777.17c | Probable 54S ribosomal protein L9, mitochondrial. (101 aa) |
| | qcr1 | Probable mitochondrial-processing peptidase subunit beta; Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (By similarity). Preferentially, cleaves after an arginine at position P2 (By similarity). Belongs to the peptidase M16 family. (457 aa) |
| | tim18 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (159 aa) |
| | mgr3 | TPR repeat-containing protein P27G11.02. (356 aa) |
| | mrx14 | Probable 54S ribosomal protein L34, mitochondrial. (108 aa) |
| | tim9 | Mitochondrial import inner membrane translocase subunit tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (84 aa) |
| | qcr10 | Cytochrome b-c1 complex subunit 10; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the in [...] (79 aa) |
| | aco2 | Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (918 aa) |
| | npl4 | Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (572 aa) |
| | atp16 | ATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (167 aa) |
| | pkp1 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial; Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism. (425 aa) |
| | mrpl9 | 54S ribosomal protein L9, mitochondrial; Belongs to the universal ribosomal protein uL3 family. (259 aa) |
| | mrpl1 | 54S ribosomal protein L1, mitochondrial; Belongs to the universal ribosomal protein uL1 family. (253 aa) |
| | cox8 | Cytochrome c oxidase polypeptide VIII, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transme [...] (66 aa) |
| | cdc48 | Cell division cycle protein 48; ATP-dependent chaperone which probably uses the energy provided by ATP hydrolysis to generate mechanical force to unfold substrate proteins, disassemble protein complexes, and disaggregate protein aggregates. By recruiting and promoting the degradation of ubiquitinated proteins, plays a role in the ubiquitin fusion degradation (UFD) pathway. Has a role in the endoplasmic reticulum- associated degradation (ERAD) pathway which mediates the cytoplasmic elimination of misfolded proteins exported from the ER. Involved in spindle disassembly. Component of the [...] (815 aa) |
| | yta12 | Mitochondrial respiratory chain complexes assembly protein rca1; Acts as a component of the m-AAA protease complex which is a ATP-dependent metalloprotease mediating degradation of non-assembled mitochondrial inner membrane proteins. The complex is necessary for the assembly of mitochondrial respiratory chain and ATPase complexes. Function both in post-translational assembly and in the turnover of mistranslated or misfolded polypeptides (By similarity); In the C-terminal section; belongs to the peptidase M41 family. (773 aa) |
| | mic10 | MICOS complex subunit mic10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (86 aa) |
| | mtx2 | Metaxin-1; Involved in transport of proteins into the mitochondrion. (271 aa) |
| | mrp7 | 54S ribosomal protein L27, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (153 aa) |
