9 items (Schizosaccharomyces pombe) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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Your Input:
	clp1	Tyrosine-protein phosphatase CDC14 homolog; Protein phosphatase which antagonizes mitotic cyclin- dependent kinase cdc2, the inactivation of which is essential for exit from mitosis. To access its substrates, is released from nucleolar sequestration during mitosis. Plays an essential in coordinating the nuclear division cycle with cytokinesis through the cytokinesis checkpoint. Involved in chromosome segregation, where it is required for meiosis I spindle dissambly as well as for establishing two consecutive chromosome segregation phases. Allows damaged actomyosin rings to be maintaine [...] (537 aa)
	SPBC17A3.03c	Probable tyrosine-protein phosphatase C17A3.03c; Belongs to the protein-tyrosine phosphatase family. (287 aa)
	pyp3	Tyrosine-protein phosphatase 3; Contributes to dephosphorylation of tyrosine 15 of cdc2. (303 aa)
	pyp2	Tyrosine-protein phosphatase 2; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2. (711 aa)
	pyp1	Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2. (550 aa)
	ptn1	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase ptn1; Acts as a phosphoinositide 3-phosphatase and regulates PtdIns(3,4,5)P3 levels. (348 aa)
	ymr1	Phosphoinositide 3-phosphatase; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P). Involved in the control of PI3P-dependent signaling and in the maintenance of endosomal system integrity (By similarity). (559 aa)
	pmp1	Tyrosine-protein phosphatase pmp1; Dual specificity phosphatase that dephosphorylates MAP kinase pmk1 on a Tyr. Has a role in chloride ion homeostasis by inactivating this pmk1 MAP kinase pathway; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (278 aa)
	SPBC17A3.06	Tyrosine-protein phosphatase yvh1; May be directly involved in signal transduction and/or cell cycle regulation. It is necessary for maintaining growth rate or spore germination. Could show both activity toward tyrosine-protein phosphate as well as with serine-protein phosphate (By similarity). (330 aa)

Your Current Organism:

Schizosaccharomyces pombe

NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPBC17A3.06	ymr1	O13632	O13819	Tyrosine-protein phosphatase yvh1; May be directly involved in signal transduction and/or cell cycle regulation. It is necessary for maintaining growth rate or spore germination. Could show both activity toward tyrosine-protein phosphate as well as with serine-protein phosphate (By similarity).	Phosphoinositide 3-phosphatase; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P). Involved in the control of PI3P-dependent signaling and in the maintenance of endosomal system integrity (By similarity).	0.619
pmp1	pyp1	O13453	P27574	Tyrosine-protein phosphatase pmp1; Dual specificity phosphatase that dephosphorylates MAP kinase pmk1 on a Tyr. Has a role in chloride ion homeostasis by inactivating this pmk1 MAP kinase pathway; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	0.522
pmp1	pyp2	O13453	P32586	Tyrosine-protein phosphatase pmp1; Dual specificity phosphatase that dephosphorylates MAP kinase pmk1 on a Tyr. Has a role in chloride ion homeostasis by inactivating this pmk1 MAP kinase pathway; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase 2; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	0.766
ptn1	ymr1	O94526	O13819	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase ptn1; Acts as a phosphoinositide 3-phosphatase and regulates PtdIns(3,4,5)P3 levels.	Phosphoinositide 3-phosphatase; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P). Involved in the control of PI3P-dependent signaling and in the maintenance of endosomal system integrity (By similarity).	0.765
pyp1	pmp1	P27574	O13453	Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	Tyrosine-protein phosphatase pmp1; Dual specificity phosphatase that dephosphorylates MAP kinase pmk1 on a Tyr. Has a role in chloride ion homeostasis by inactivating this pmk1 MAP kinase pathway; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.522
pyp1	pyp2	P27574	P32586	Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	Tyrosine-protein phosphatase 2; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	0.844
pyp1	pyp3	P27574	P32587	Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	Tyrosine-protein phosphatase 3; Contributes to dephosphorylation of tyrosine 15 of cdc2.	0.597
pyp2	pmp1	P32586	O13453	Tyrosine-protein phosphatase 2; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	Tyrosine-protein phosphatase pmp1; Dual specificity phosphatase that dephosphorylates MAP kinase pmk1 on a Tyr. Has a role in chloride ion homeostasis by inactivating this pmk1 MAP kinase pathway; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.766
pyp2	pyp1	P32586	P27574	Tyrosine-protein phosphatase 2; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	0.844
pyp2	pyp3	P32586	P32587	Tyrosine-protein phosphatase 2; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	Tyrosine-protein phosphatase 3; Contributes to dephosphorylation of tyrosine 15 of cdc2.	0.568
pyp3	pyp1	P32587	P27574	Tyrosine-protein phosphatase 3; Contributes to dephosphorylation of tyrosine 15 of cdc2.	Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	0.597
pyp3	pyp2	P32587	P32586	Tyrosine-protein phosphatase 3; Contributes to dephosphorylation of tyrosine 15 of cdc2.	Tyrosine-protein phosphatase 2; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2.	0.568
ymr1	SPBC17A3.06	O13819	O13632	Phosphoinositide 3-phosphatase; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P). Involved in the control of PI3P-dependent signaling and in the maintenance of endosomal system integrity (By similarity).	Tyrosine-protein phosphatase yvh1; May be directly involved in signal transduction and/or cell cycle regulation. It is necessary for maintaining growth rate or spore germination. Could show both activity toward tyrosine-protein phosphate as well as with serine-protein phosphate (By similarity).	0.619
ymr1	ptn1	O13819	O94526	Phosphoinositide 3-phosphatase; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P). Involved in the control of PI3P-dependent signaling and in the maintenance of endosomal system integrity (By similarity).	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase ptn1; Acts as a phosphoinositide 3-phosphatase and regulates PtdIns(3,4,5)P3 levels.	0.765