node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
act1 | pmk1 | P10989 | Q92398 | Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Mitogen-activated protein kinase spm1; Regulates cell integrity and functions coordinately with the protein kinase C pathway (pck1 and pck2). Involved the regulation of wall architecture, cell shape, cytokinesis in exponential and stationary phase, and metabolism of ions. | 0.687 |
act1 | sty1 | P10989 | Q09892 | Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...] | 0.872 |
atf1 | mkh1 | P52890 | Q10407 | Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26. | MAP kinase kinase kinase mkh1; May regulate cell morphology, cell wall integrity, salt resistance, cell cycle reentry from stationary-phase arrest, and filamentous growth in response to stress. Activates the MAP kinase kinase skh1/pek1 by phosphorylation. | 0.510 |
atf1 | pek1 | P52890 | Q9Y884 | Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26. | MAP kinase kinase skh1/pek1; Involved in the mkh1 signal transduction pathway that plays a role in cell wall integrity. Activates spm1/pmk1 via phosphorylation. | 0.466 |
atf1 | pmk1 | P52890 | Q92398 | Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26. | Mitogen-activated protein kinase spm1; Regulates cell integrity and functions coordinately with the protein kinase C pathway (pck1 and pck2). Involved the regulation of wall architecture, cell shape, cytokinesis in exponential and stationary phase, and metabolism of ions. | 0.891 |
atf1 | sty1 | P52890 | Q09892 | Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26. | Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...] | 0.999 |
atf1 | win1 | P52890 | O74304 | Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26. | MAP kinase kinase kinase win1; Involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Activates the wis1 MAP kinase kinase by phosphorylation. | 0.675 |
atf1 | wis1 | P52890 | P33886 | Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26. | Protein kinase wis1; Dosage-dependent regulator of mitosis with serine/ threonine protein kinase activity. May play a role in the integration of nutritional sensing with the control over entry into mitosis. It may interact with cdc25, wee1 and win1. May activate sty1. | 0.934 |
atf1 | wis4 | P52890 | O14299 | Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26. | MAP kinase kinase kinase wis4; Involved in a signal transduction pathway that is activated in under conditions of heat shock, oxidative stress or limited nutrition. Unlike win1, it is not activated by changes in the osmolarity of the extracellular environment. Activates the wis1 MAP kinase kinase by phosphorylation. | 0.675 |
mkh1 | atf1 | Q10407 | P52890 | MAP kinase kinase kinase mkh1; May regulate cell morphology, cell wall integrity, salt resistance, cell cycle reentry from stationary-phase arrest, and filamentous growth in response to stress. Activates the MAP kinase kinase skh1/pek1 by phosphorylation. | Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26. | 0.510 |
mkh1 | pek1 | Q10407 | Q9Y884 | MAP kinase kinase kinase mkh1; May regulate cell morphology, cell wall integrity, salt resistance, cell cycle reentry from stationary-phase arrest, and filamentous growth in response to stress. Activates the MAP kinase kinase skh1/pek1 by phosphorylation. | MAP kinase kinase skh1/pek1; Involved in the mkh1 signal transduction pathway that plays a role in cell wall integrity. Activates spm1/pmk1 via phosphorylation. | 0.998 |
mkh1 | pmk1 | Q10407 | Q92398 | MAP kinase kinase kinase mkh1; May regulate cell morphology, cell wall integrity, salt resistance, cell cycle reentry from stationary-phase arrest, and filamentous growth in response to stress. Activates the MAP kinase kinase skh1/pek1 by phosphorylation. | Mitogen-activated protein kinase spm1; Regulates cell integrity and functions coordinately with the protein kinase C pathway (pck1 and pck2). Involved the regulation of wall architecture, cell shape, cytokinesis in exponential and stationary phase, and metabolism of ions. | 0.918 |
mkh1 | sty1 | Q10407 | Q09892 | MAP kinase kinase kinase mkh1; May regulate cell morphology, cell wall integrity, salt resistance, cell cycle reentry from stationary-phase arrest, and filamentous growth in response to stress. Activates the MAP kinase kinase skh1/pek1 by phosphorylation. | Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...] | 0.597 |
mkh1 | win1 | Q10407 | O74304 | MAP kinase kinase kinase mkh1; May regulate cell morphology, cell wall integrity, salt resistance, cell cycle reentry from stationary-phase arrest, and filamentous growth in response to stress. Activates the MAP kinase kinase skh1/pek1 by phosphorylation. | MAP kinase kinase kinase win1; Involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Activates the wis1 MAP kinase kinase by phosphorylation. | 0.509 |
mkh1 | wis1 | Q10407 | P33886 | MAP kinase kinase kinase mkh1; May regulate cell morphology, cell wall integrity, salt resistance, cell cycle reentry from stationary-phase arrest, and filamentous growth in response to stress. Activates the MAP kinase kinase skh1/pek1 by phosphorylation. | Protein kinase wis1; Dosage-dependent regulator of mitosis with serine/ threonine protein kinase activity. May play a role in the integration of nutritional sensing with the control over entry into mitosis. It may interact with cdc25, wee1 and win1. May activate sty1. | 0.855 |
mkh1 | wis4 | Q10407 | O14299 | MAP kinase kinase kinase mkh1; May regulate cell morphology, cell wall integrity, salt resistance, cell cycle reentry from stationary-phase arrest, and filamentous growth in response to stress. Activates the MAP kinase kinase skh1/pek1 by phosphorylation. | MAP kinase kinase kinase wis4; Involved in a signal transduction pathway that is activated in under conditions of heat shock, oxidative stress or limited nutrition. Unlike win1, it is not activated by changes in the osmolarity of the extracellular environment. Activates the wis1 MAP kinase kinase by phosphorylation. | 0.525 |
pek1 | atf1 | Q9Y884 | P52890 | MAP kinase kinase skh1/pek1; Involved in the mkh1 signal transduction pathway that plays a role in cell wall integrity. Activates spm1/pmk1 via phosphorylation. | Transcription factor atf1; Transcription factor required for sexual development and entry into stationary phase. Binds and activates meiotic recombination hot spot ade6-M26. | 0.466 |
pek1 | mkh1 | Q9Y884 | Q10407 | MAP kinase kinase skh1/pek1; Involved in the mkh1 signal transduction pathway that plays a role in cell wall integrity. Activates spm1/pmk1 via phosphorylation. | MAP kinase kinase kinase mkh1; May regulate cell morphology, cell wall integrity, salt resistance, cell cycle reentry from stationary-phase arrest, and filamentous growth in response to stress. Activates the MAP kinase kinase skh1/pek1 by phosphorylation. | 0.998 |
pek1 | pmk1 | Q9Y884 | Q92398 | MAP kinase kinase skh1/pek1; Involved in the mkh1 signal transduction pathway that plays a role in cell wall integrity. Activates spm1/pmk1 via phosphorylation. | Mitogen-activated protein kinase spm1; Regulates cell integrity and functions coordinately with the protein kinase C pathway (pck1 and pck2). Involved the regulation of wall architecture, cell shape, cytokinesis in exponential and stationary phase, and metabolism of ions. | 0.993 |
pek1 | sty1 | Q9Y884 | Q09892 | MAP kinase kinase skh1/pek1; Involved in the mkh1 signal transduction pathway that plays a role in cell wall integrity. Activates spm1/pmk1 via phosphorylation. | Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...] | 0.814 |