STRINGSTRING
hsp90 hsp90 cdc42 cdc42 hob3 hob3 act1 act1 hob1 hob1 dss4 dss4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hsp90Heat shock protein 90 homolog; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Interacts with the wee1 protein kinase; which re [...] (704 aa)
cdc42Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily. (192 aa)
hob3Protein hob3; Involved in cytokinesis and septation where it has a role in the localization of F-actin. (264 aa)
act1Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (375 aa)
hob1Protein hob1; Has a role in DNA damage signaling as a part of stress response processes. (466 aa)
dss4Guanine nucleotide exchange factor MSS4 homolog; Guanine-nucleotide-releasing protein that acts on members of the sec4/ypt1/rab subfamily. (100 aa)
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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