6 items (Schizosaccharomyces pombe) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	wsp1	Wiskott-Aldrich syndrome protein homolog 1; Has a role in regulating actin assembly, so regulating polarized growth. (574 aa)
	cdc12	Cell division control protein 12; Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, thus preventing subunit addition and dissociation. In the presence of profilin, nucleates actin filaments that grow rapidly from their barbed ends. Belongs to the formin homology family. BNI1 subfamily. (1841 aa)
	cdc8	Tropomyosin; Forms part of the F-actin contractile ring during cytokinesis. (161 aa)
	cdc42	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily. (192 aa)
	act1	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (375 aa)
	for3	Formin-3; Involved in controlling polarized cell growth. Required for interphase actin cable formation and microtubule organization. Belongs to the formin homology family. (1461 aa)

Your Current Organism:

Schizosaccharomyces pombe

NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
act1	cdc12	P10989	Q10059	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	Cell division control protein 12; Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, thus preventing subunit addition and dissociation. In the presence of profilin, nucleates actin filaments that grow rapidly from their barbed ends. Belongs to the formin homology family. BNI1 subfamily.	0.995
act1	cdc42	P10989	Q01112	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	0.995
act1	cdc8	P10989	Q02088	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	Tropomyosin; Forms part of the F-actin contractile ring during cytokinesis.	0.999
act1	for3	P10989	O94532	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	Formin-3; Involved in controlling polarized cell growth. Required for interphase actin cable formation and microtubule organization. Belongs to the formin homology family.	0.976
act1	wsp1	P10989	O36027	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	Wiskott-Aldrich syndrome protein homolog 1; Has a role in regulating actin assembly, so regulating polarized growth.	0.992
cdc12	act1	Q10059	P10989	Cell division control protein 12; Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, thus preventing subunit addition and dissociation. In the presence of profilin, nucleates actin filaments that grow rapidly from their barbed ends. Belongs to the formin homology family. BNI1 subfamily.	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	0.995
cdc12	cdc42	Q10059	Q01112	Cell division control protein 12; Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, thus preventing subunit addition and dissociation. In the presence of profilin, nucleates actin filaments that grow rapidly from their barbed ends. Belongs to the formin homology family. BNI1 subfamily.	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	0.984
cdc12	cdc8	Q10059	Q02088	Cell division control protein 12; Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, thus preventing subunit addition and dissociation. In the presence of profilin, nucleates actin filaments that grow rapidly from their barbed ends. Belongs to the formin homology family. BNI1 subfamily.	Tropomyosin; Forms part of the F-actin contractile ring during cytokinesis.	0.939
cdc12	for3	Q10059	O94532	Cell division control protein 12; Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, thus preventing subunit addition and dissociation. In the presence of profilin, nucleates actin filaments that grow rapidly from their barbed ends. Belongs to the formin homology family. BNI1 subfamily.	Formin-3; Involved in controlling polarized cell growth. Required for interphase actin cable formation and microtubule organization. Belongs to the formin homology family.	0.963
cdc12	wsp1	Q10059	O36027	Cell division control protein 12; Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, thus preventing subunit addition and dissociation. In the presence of profilin, nucleates actin filaments that grow rapidly from their barbed ends. Belongs to the formin homology family. BNI1 subfamily.	Wiskott-Aldrich syndrome protein homolog 1; Has a role in regulating actin assembly, so regulating polarized growth.	0.806
cdc42	act1	Q01112	P10989	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	0.995
cdc42	cdc12	Q01112	Q10059	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	Cell division control protein 12; Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, thus preventing subunit addition and dissociation. In the presence of profilin, nucleates actin filaments that grow rapidly from their barbed ends. Belongs to the formin homology family. BNI1 subfamily.	0.984
cdc42	cdc8	Q01112	Q02088	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	Tropomyosin; Forms part of the F-actin contractile ring during cytokinesis.	0.749
cdc42	for3	Q01112	O94532	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	Formin-3; Involved in controlling polarized cell growth. Required for interphase actin cable formation and microtubule organization. Belongs to the formin homology family.	0.996
cdc42	wsp1	Q01112	O36027	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	Wiskott-Aldrich syndrome protein homolog 1; Has a role in regulating actin assembly, so regulating polarized growth.	0.951
cdc8	act1	Q02088	P10989	Tropomyosin; Forms part of the F-actin contractile ring during cytokinesis.	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	0.999
cdc8	cdc12	Q02088	Q10059	Tropomyosin; Forms part of the F-actin contractile ring during cytokinesis.	Cell division control protein 12; Plays a role in the cell cycle. Involved in cytokinesis. Component of the cell division ring. In the absence of profilin, caps the barbed end of actin filaments, thus preventing subunit addition and dissociation. In the presence of profilin, nucleates actin filaments that grow rapidly from their barbed ends. Belongs to the formin homology family. BNI1 subfamily.	0.939
cdc8	cdc42	Q02088	Q01112	Tropomyosin; Forms part of the F-actin contractile ring during cytokinesis.	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	0.749
cdc8	for3	Q02088	O94532	Tropomyosin; Forms part of the F-actin contractile ring during cytokinesis.	Formin-3; Involved in controlling polarized cell growth. Required for interphase actin cable formation and microtubule organization. Belongs to the formin homology family.	0.815
cdc8	wsp1	Q02088	O36027	Tropomyosin; Forms part of the F-actin contractile ring during cytokinesis.	Wiskott-Aldrich syndrome protein homolog 1; Has a role in regulating actin assembly, so regulating polarized growth.	0.725