5 items (Schizosaccharomyces pombe) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdc15	Cell division control protein 15; After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Appears to mediate cytoskeletal rearrangements required for cytokinesis. Essential for viability. (927 aa)
	cdc42	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily. (192 aa)
	act1	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (375 aa)
	hob1	Protein hob1; Has a role in DNA damage signaling as a part of stress response processes. (466 aa)
	rpe1	Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)

Your Current Organism:

Schizosaccharomyces pombe

NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
act1	cdc15	P10989	Q09822	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	Cell division control protein 15; After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Appears to mediate cytoskeletal rearrangements required for cytokinesis. Essential for viability.	0.954
act1	cdc42	P10989	Q01112	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	0.995
act1	hob1	P10989	O74352	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	Protein hob1; Has a role in DNA damage signaling as a part of stress response processes.	0.958
cdc15	act1	Q09822	P10989	Cell division control protein 15; After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Appears to mediate cytoskeletal rearrangements required for cytokinesis. Essential for viability.	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	0.954
cdc15	cdc42	Q09822	Q01112	Cell division control protein 15; After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Appears to mediate cytoskeletal rearrangements required for cytokinesis. Essential for viability.	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	0.750
cdc15	hob1	Q09822	O74352	Cell division control protein 15; After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Appears to mediate cytoskeletal rearrangements required for cytokinesis. Essential for viability.	Protein hob1; Has a role in DNA damage signaling as a part of stress response processes.	0.522
cdc42	act1	Q01112	P10989	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	0.995
cdc42	cdc15	Q01112	Q09822	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	Cell division control protein 15; After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Appears to mediate cytoskeletal rearrangements required for cytokinesis. Essential for viability.	0.750
cdc42	hob1	Q01112	O74352	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	Protein hob1; Has a role in DNA damage signaling as a part of stress response processes.	0.731
hob1	act1	O74352	P10989	Protein hob1; Has a role in DNA damage signaling as a part of stress response processes.	Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	0.958
hob1	cdc15	O74352	Q09822	Protein hob1; Has a role in DNA damage signaling as a part of stress response processes.	Cell division control protein 15; After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Appears to mediate cytoskeletal rearrangements required for cytokinesis. Essential for viability.	0.522
hob1	cdc42	O74352	Q01112	Protein hob1; Has a role in DNA damage signaling as a part of stress response processes.	Cell division control protein 42 homolog; Involved in development of cell polarity during the cell division cycle; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	0.731