node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
act1 | dis3 | P10989 | P37202 | Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Exosome complex exonuclease dis3; Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...] | 0.419 |
act1 | pck1 | P10989 | P36582 | Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Protein kinase C-like 1; Involved in the control of the cell shape. Target of the inhibitor staurosporine; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.695 |
act1 | sty1 | P10989 | Q09892 | Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...] | 0.872 |
dis3 | act1 | P37202 | P10989 | Exosome complex exonuclease dis3; Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...] | Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | 0.419 |
dis3 | sts5 | P37202 | O74454 | Exosome complex exonuclease dis3; Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...] | Protein sts5; Required for the maintenance of cell shape during interphase. Required for localization of cortical actin to the growing tips before mitosis. | 0.698 |
pck1 | act1 | P36582 | P10989 | Protein kinase C-like 1; Involved in the control of the cell shape. Target of the inhibitor staurosporine; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | 0.695 |
pck1 | sts5 | P36582 | O74454 | Protein kinase C-like 1; Involved in the control of the cell shape. Target of the inhibitor staurosporine; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | Protein sts5; Required for the maintenance of cell shape during interphase. Required for localization of cortical actin to the growing tips before mitosis. | 0.731 |
pyp1 | sts5 | P27574 | O74454 | Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2. | Protein sts5; Required for the maintenance of cell shape during interphase. Required for localization of cortical actin to the growing tips before mitosis. | 0.594 |
pyp1 | sty1 | P27574 | Q09892 | Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2. | Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...] | 0.980 |
pyp1 | wis1 | P27574 | P33886 | Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2. | Protein kinase wis1; Dosage-dependent regulator of mitosis with serine/ threonine protein kinase activity. May play a role in the integration of nutritional sensing with the control over entry into mitosis. It may interact with cdc25, wee1 and win1. May activate sty1. | 0.931 |
sts5 | dis3 | O74454 | P37202 | Protein sts5; Required for the maintenance of cell shape during interphase. Required for localization of cortical actin to the growing tips before mitosis. | Exosome complex exonuclease dis3; Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...] | 0.698 |
sts5 | pck1 | O74454 | P36582 | Protein sts5; Required for the maintenance of cell shape during interphase. Required for localization of cortical actin to the growing tips before mitosis. | Protein kinase C-like 1; Involved in the control of the cell shape. Target of the inhibitor staurosporine; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.731 |
sts5 | pyp1 | O74454 | P27574 | Protein sts5; Required for the maintenance of cell shape during interphase. Required for localization of cortical actin to the growing tips before mitosis. | Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2. | 0.594 |
sts5 | wis1 | O74454 | P33886 | Protein sts5; Required for the maintenance of cell shape during interphase. Required for localization of cortical actin to the growing tips before mitosis. | Protein kinase wis1; Dosage-dependent regulator of mitosis with serine/ threonine protein kinase activity. May play a role in the integration of nutritional sensing with the control over entry into mitosis. It may interact with cdc25, wee1 and win1. May activate sty1. | 0.464 |
sty1 | act1 | Q09892 | P10989 | Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...] | Actin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | 0.872 |
sty1 | pyp1 | Q09892 | P27574 | Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...] | Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2. | 0.980 |
sty1 | wis1 | Q09892 | P33886 | Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...] | Protein kinase wis1; Dosage-dependent regulator of mitosis with serine/ threonine protein kinase activity. May play a role in the integration of nutritional sensing with the control over entry into mitosis. It may interact with cdc25, wee1 and win1. May activate sty1. | 0.998 |
wis1 | pyp1 | P33886 | P27574 | Protein kinase wis1; Dosage-dependent regulator of mitosis with serine/ threonine protein kinase activity. May play a role in the integration of nutritional sensing with the control over entry into mitosis. It may interact with cdc25, wee1 and win1. May activate sty1. | Tyrosine-protein phosphatase 1; Plays a role in inhibiting the onset of mitosis. Dephosphorylates sty1/spc1 and wis1/spc2/sty2. | 0.931 |
wis1 | sts5 | P33886 | O74454 | Protein kinase wis1; Dosage-dependent regulator of mitosis with serine/ threonine protein kinase activity. May play a role in the integration of nutritional sensing with the control over entry into mitosis. It may interact with cdc25, wee1 and win1. May activate sty1. | Protein sts5; Required for the maintenance of cell shape during interphase. Required for localization of cortical actin to the growing tips before mitosis. | 0.464 |
wis1 | sty1 | P33886 | Q09892 | Protein kinase wis1; Dosage-dependent regulator of mitosis with serine/ threonine protein kinase activity. May play a role in the integration of nutritional sensing with the control over entry into mitosis. It may interact with cdc25, wee1 and win1. May activate sty1. | Mitogen-activated protein kinase sty1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in osmoregulation and stress response pathways leading to an efficient start of sexual differentiation. Supports translation initiation and facilitates adaptation to environmental stress in part through reducing eIF2-alpha phosphorylation. Links the cell-cycle G2/M control with changes in the extracellular environment that a [...] | 0.998 |