STRINGSTRING
utp24 utp24 rps1002 rps1002 rpl8 rpl8 rps2401 rps2401 ebp2 ebp2 imp4 imp4 imp3 imp3 nan1 nan1 rrp40 rrp40 mpp10 mpp10 tsr1 tsr1 pno1 pno1 utp21 utp21 rps1201 rps1201 rpl44 rpl44 mpp6 mpp6 mtr4 mtr4 rps5 rps5 rpp203 rpp203 rio1 rio1 rpl1902 rpl1902 rpl2102 rpl2102 rpl1602 rpl1602 rrp41 rrp41 rrp46 rrp46 rpl3201 rpl3201 las1 las1 ulp1 ulp1 rps1701 rps1701 rpl1601 rpl1601 nop14 nop14 rpl1702 rpl1702 csl4 csl4 rps2402 rps2402 utp20 utp20 enp1 enp1 rrp42 rrp42 rps3 rps3 rpl701 rpl701 utp4 utp4 ppp1 ppp1 utp10 utp10 utp6 utp6 rps2501 rps2501 rpl13 rpl13 rpl502 rpl502 rps29 rps29 rps27 rps27 sof1 sof1 rpl2502 rpl2502 erb1 erb1 cti1 cti1 rpl2702 rpl2702 snu13 snu13 mis3 mis3 grn1 grn1 rrp5 rrp5 rpl101 rpl101 rpp0 rpp0 rps2 rps2 rps20 rps20 rpl15 rpl15 rpl35 rpl35 rrp45 rrp45 utp25 utp25 rpl14 rpl14 utp15 utp15 noc4 noc4 rex4 rex4 nop56 nop56 bms1 bms1 rpl3602 rpl3602 utp22 utp22 rrp7 rrp7 rps1501 rps1501 ipi1 ipi1 rpl3702 rpl3702 rps21 rps21 rpl39 rpl39 rps1401 rps1401 rps1402 rps1402 rps2201 rps2201 rps2202 rps2202 rpl2301 rpl2301 rpl2302 rpl2302 rps1601 rps1601 rps1602 rps1602 rps1801 rps1801 rps1802 rps1802 rpl2001 rpl2001 rpl2002 rpl2002 rpl801 rpl801 rpl802 rpl802 rpl803 rpl803 rps1101 rps1101 rps1102 rps1102 rps23 rps23 rps2302 rps2302 rpl1101 rpl1101 rpl1102 rpl1102 rps2801 rps2801 rps2802 rps2802 rpl1201 rpl1201 rpl1202 rpl1202 rpp101 rpp101 rpp102 rpp102 rps13 rps13 fib1 fib1 rpl402 rpl402 rpl302 rpl302 rpl2802 rpl2802 dis3 dis3 hhp1 hhp1 hhp2 hhp2 rpl301 rpl301 rpl3001 rpl3001 rpl2801 rpl2801 rps1901 rps1901 utp18 utp18 rpl26 rpl26 rpl6 rpl6 rpp1 rpp1 utp14 utp14 rps401 rps401 dip2 dip2 rix1 rix1 eri1 eri1 rpl1001 rpl1001 rrp4 rrp4 rps901 rps901 rok1 rok1 rps101 rps101 rcl1 rcl1 rps7 rps7 utp11 utp11 mra1 mra1 rrp6 rrp6 bud23 bud23 ltv1 ltv1 rpl1801 rpl1801 rrp43 rrp43 rpl901 rpl901 crb3 crb3 rpp40 rpp40 utp3 utp3 rpl1802 rpl1802 rpl2401 rpl2401 rpl3601 rpl3601 rpl29 rpl29 rps602 rps602 pwp2 pwp2 dhx37 dhx37 utp5 utp5 dbp8 dbp8 rps502 rps502 rps403 rps403 utp7 utp7 rrp3 rrp3 rrp36 rrp36 rpl1002 rpl1002 rps802 rps802 rrp9 rrp9 rps1702 rps1702 mtr3 mtr3 nop58 nop58 rio2 rio2 rpl31 rpl31 ytm1 ytm1 rpl1502 rpl1502 rpl35A01 rpl35A01 utp13 utp13 rpl3801 rpl3801 rps402 rps402 rps2602 rps2602 rpl42 rpl42 nob1 nob1 rps1502 rps1502 grc3 grc3 rpl2101 rpl2101 rps001 rps001 rpr2 rpr2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
utp24rRNA-processing protein fcf1; Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites (By similarity). Belongs to the UTP23/FCF1 family. FCF1 subfamily. (192 aa)
rps100240S ribosomal protein S10-B. (147 aa)
rpl860S ribosomal protein L8; Belongs to the eukaryotic ribosomal protein eL8 family. (259 aa)
rps240140S ribosomal protein S24-A. (134 aa)
ebp2Probable rRNA-processing protein ebp2; Required for the processing of the 27S pre-rRNA. (333 aa)
imp4U3 small nucleolar ribonucleoprotein protein imp4; Component of the U3 small nucleolar ribonucleoprotein. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing (By similarity). (289 aa)
imp3U3 small nucleolar ribonucleoprotein protein imp3; Component of the U3 small nucleolar ribonucleoprotein. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing (By similarity). (183 aa)
nan1U3 small nucleolar RNA-associated protein 17; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t- UTPs) (By similarity). (806 aa)
rrp40Exosome complex component rrp40; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplas [...] (240 aa)
mpp10U3 small nucleolar ribonucleoprotein protein mpp10; Component of the U3 small nucleolar ribonucleoprotein. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing (By similarity). (598 aa)
tsr1Ribosome biogenesis protein tsr1; Required for 40S ribosomal subunit synthesis. Required for normal export of the pre-40S particles from the nucleus to the cytoplasm (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily. (783 aa)
pno1Pre-rRNA-processing protein pno1; Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species. (241 aa)
utp21U3 small nucleolar RNA-associated protein 21 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (902 aa)
rps120140S ribosomal protein S12-A. (145 aa)
rpl44Probable 60S ribosomal protein L28e; Belongs to the eukaryotic ribosomal protein eL28 family. (134 aa)
mpp6Uncharacterized protein UNK4.11c; Belongs to the MPP6 family. (188 aa)
mtr4ATP-dependent RNA helicase mtr4; Component of the TRAMP complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information. Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates (By similarity). Required for heterochromatic gene silencing at centromeric repeats by either exosome- or RNAi-mediated degradation of heterochromatic transcripts. (1117 aa)
rps540S ribosomal protein S5-A. (203 aa)
rpp20360S acidic ribosomal protein P2-C; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. (110 aa)
rio1Serine/threonine-protein kinase rio1; Required for the final endonucleolytic cleavage at site D converting 20S pre-rRNA into the mature 18S rRNA. Required for the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). (497 aa)
rpl190260S ribosomal protein L19-B. (193 aa)
rpl210260S ribosomal protein L21-B. (160 aa)
rpl160260S ribosomal protein L16-A. (197 aa)
rrp41Exosome complex component ski6; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm [...] (242 aa)
rrp46Exosome complex component rrp46; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplas [...] (226 aa)
rpl320160S ribosomal protein L32-B. (127 aa)
las1Pre-rRNA-processing protein las1; Required for both pre-rRNA processing and heterochromatic gene silencing. (470 aa)
ulp1Ubiquitin-like-specific protease 1; A cysteine protease that proteolytically removes the C- terminus of pmt3. (568 aa)
rps170140S ribosomal protein S17-A. (131 aa)
rpl160160S ribosomal protein L16-B. (197 aa)
nop14Probable nucleolar complex protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity). (827 aa)
rpl170260S ribosomal protein L17-B. (187 aa)
csl4Exosome complex component csl4; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm [...] (181 aa)
rps240240S ribosomal protein S24-B. (134 aa)
utp20U3 small nucleolar RNA-associated protein 20; Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (2493 aa)
enp1Uncharacterized protein C13G1.09; Belongs to the bystin family. (449 aa)
rrp42Exosome complex component rrp42; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplas [...] (299 aa)
rps340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (249 aa)
rpl70160S ribosomal protein L7-C. (251 aa)
utp4U3 small nucleolar RNA-associated protein 4; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t- UTPs) (By similarity). (710 aa)
ppp1Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (607 aa)
utp10U3 small nucleolar RNA-associated protein 10; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t- UTPs). Involved in ribosome biosynthesis (By similarity). (1649 aa)
utp6U3 small nucleolar RNA-associated protein 6; Component of the SSU processome, a pre-ribosomal particle required for the maturation of the 18S rRNA from the 35S pre-rRNA precursor. (488 aa)
rps250140S ribosomal protein S25-B; Belongs to the eukaryotic ribosomal protein eS25 family. (88 aa)
rpl1360S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (208 aa)
rpl50260S ribosomal protein L5-B; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] (294 aa)
rps2940S ribosomal protein S29; Belongs to the universal ribosomal protein uS14 family. (56 aa)
rps2740S ribosomal protein S27. (83 aa)
sof1Protein sof1; Required for ribosomal RNA processing. (436 aa)
rpl250260S ribosomal protein L25-B; This protein binds to a specific region on the 26S rRNA. Belongs to the universal ribosomal protein uL23 family. (141 aa)
erb1Ribosome biogenesis protein erb1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (740 aa)
cti1Exosome complex protein C1739.07; Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites (By similarity); Belongs to the C1D family. (133 aa)
rpl270260S ribosomal protein L27-B. (136 aa)
snu1313 kDa ribonucleoprotein-associated protein; Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity). (125 aa)
mis3KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (327 aa)
grn1GTPase grn1; Required for optimal growth. Required for normal processing of ribosomal pre-rRNA. Required for nuclear export of ribosomal protein rpl2501; Belongs to the TRAFAC class YlqF/YawG GTPase family. (470 aa)
rrp5rRNA biogenesis protein rrp5; Involved in the biogenesis of rRNA. Required for the formation of 18S and 5.8S rRNA (By similarity). (1690 aa)
rpl10160S ribosomal protein L1-B. (216 aa)
rpp060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (312 aa)
rps240S ribosomal protein S2. (253 aa)
rps2040S ribosomal protein S20; Belongs to the universal ribosomal protein uS10 family. (118 aa)
rpl1560S ribosomal protein L15-A. (201 aa)
rpl3560S ribosomal protein L35; Belongs to the universal ribosomal protein uL29 family. (122 aa)
rrp45Exosome complex component rrp45; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplas [...] (291 aa)
utp25U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (652 aa)
rpl1460S ribosomal protein L14; Belongs to the eukaryotic ribosomal protein eL14 family. (134 aa)
utp15U3 small nucleolar RNA-associated protein 15; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t- UTPs) (By similarity). (494 aa)
noc4Uncharacterized protein C1604.06c. (485 aa)
rex4RNA exonuclease 4; Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity); Belongs to the REXO4 family. (260 aa)
nop56Nucleolar protein 56; Required for 60S ribosomal subunit synthesis. (497 aa)
bms1Ribosome biogenesis protein bms1; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. BMS1 subfamily. (1121 aa)
rpl360260S ribosomal protein L36-B. (99 aa)
utp22U3 small nucleolar RNA-associated protein 22; Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (1097 aa)
rrp7Ribosomal RNA-processing protein 7; Plays an important role in the synthesis of 18S rRNA but is not required for the 5.8S and 25S pathway. Is necessary for the cleavage at site A2 (By similarity); Belongs to the RRP7 family. (238 aa)
rps150140S ribosomal protein S15-A. (153 aa)
ipi1Pre-rRNA-processing protein ipi1; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA. (413 aa)
rpl370260S ribosomal protein L37-B; Binds to the 23S rRNA. (91 aa)
rps2140S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability. Belongs to the eukaryotic ribosomal protein eS21 family. (87 aa)
rpl3960S ribosomal protein L39. (51 aa)
rps140140S ribosomal protein S14-A. (139 aa)
rps140240S ribosomal protein S14-B. (139 aa)
rps220140S ribosomal protein S22-A. (130 aa)
rps220240S ribosomal protein S22-B. (130 aa)
rpl230160S ribosomal protein L23-A. (139 aa)
rpl230260S ribosomal protein L23-B. (139 aa)
rps160140S ribosomal protein S16-A. (140 aa)
rps160240S ribosomal protein S16-B. (140 aa)
rps180140S ribosomal protein S18-A; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA. (152 aa)
rps180240S ribosomal protein S18-B; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA. (152 aa)
rpl200160S ribosomal protein L20-A. (176 aa)
rpl200260S ribosomal protein L20-B. (176 aa)
rpl80160S ribosomal protein L2-A. (253 aa)
rpl80260S ribosomal protein L2-B. (253 aa)
rpl80360S ribosomal protein L2-C. (253 aa)
rps110140S ribosomal protein S11-A. (152 aa)
rps110240S ribosomal protein S11-B. (152 aa)
rps2340S ribosomal protein S23-A; Belongs to the universal ribosomal protein uS12 family. (143 aa)
rps230240S ribosomal protein S23-B; Belongs to the universal ribosomal protein uS12 family. (143 aa)
rpl110160S ribosomal protein L11-A; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throu [...] (174 aa)
rpl110260S ribosomal protein L11-B; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throu [...] (174 aa)
rps280140S ribosomal protein S28-A. (68 aa)
rps280240S ribosomal protein S28-B. (68 aa)
rpl120160S ribosomal protein L12-A; This protein binds directly to 26S ribosomal RNA. Belongs to the universal ribosomal protein uL11 family. (165 aa)
rpl120260S ribosomal protein L12-B; This protein binds directly to 26S ribosomal RNA. Belongs to the universal ribosomal protein uL11 family. (165 aa)
rpp10160S acidic ribosomal protein P1-alpha 1; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. (109 aa)
rpp10260S acidic ribosomal protein P1-alpha 3; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. (110 aa)
rps1340S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
fib1rRNA 2'-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification [...] (305 aa)
rpl40260S ribosomal protein L4-A. (363 aa)
rpl30260S ribosomal protein L3-B; Belongs to the universal ribosomal protein uL3 family. (388 aa)
rpl280260S ribosomal protein L28-A. (148 aa)
dis3Exosome complex exonuclease dis3; Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. [...] (970 aa)
hhp1Casein kinase I homolog hhp1; Involved in DNA repair. Has a probable role in repairing alkylated DNA and may regulate the activity of protein(s) involved in double strand break repair caused by gamma rays; Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. (365 aa)
hhp2Casein kinase I homolog hhp2; Involved in DNA repair. May regulate the activity of protein(s) involved in double strand break repair caused by gamma rays; Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. (400 aa)
rpl30160S ribosomal protein L3-A; Belongs to the universal ribosomal protein uL3 family. (388 aa)
rpl300160S ribosomal protein L30-1. (109 aa)
rpl280160S ribosomal protein L28-B. (148 aa)
rps190140S ribosomal protein S19-A. (144 aa)
utp18Probable U3 small nucleolar RNA-associated protein 18; Involved in nucleolar processing of pre-18S ribosomal RNA. (519 aa)
rpl2660S ribosomal protein L26; Belongs to the universal ribosomal protein uL24 family. (126 aa)
rpl660S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family. (195 aa)
rpp1Probable ribonuclease P protein subunit 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (235 aa)
utp14Uncharacterized protein C57A7.06. (929 aa)
rps40140S ribosomal protein S4-A; Belongs to the eukaryotic ribosomal protein eS4 family. (262 aa)
dip2Uncharacterized WD repeat-containing protein C3D6.12; Belongs to the WD repeat WDR3/UTP12 family. (922 aa)
rix1Pre-rRNA-processing protein rix1; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre- 60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor mdn1 (By similarity). Also required for heterochromatic gene silencing. (828 aa)
eri13'-5' exonuclease eri1; RNA exonuclease that acts as a negative regulator of RNA interference (RNAi). Acts by degrading the 3'-overhangs of double- stranded short interfering RNAs (siRNAs). Represses the accumulation of heterochromatic siRNAs leading to negative regulation of the RNAi- mediated heterochromoatin assembly. Also involved in rRNA biogenesis, trimming the 5.8S ribosomal RNA (rRNA) from a slightly longer pre-5.8S RNA in the cytoplasm. (313 aa)
rpl100160S ribosomal protein L10-A. (221 aa)
rrp4Exosome complex component rrp4; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm [...] (329 aa)
rps90140S ribosomal protein S9-A; Belongs to the universal ribosomal protein uS4 family. (191 aa)
rok1ATP-dependent RNA helicase rok1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA. (481 aa)
rps10140S ribosomal protein S1-A. (252 aa)
rcl1Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. (363 aa)
rps740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (195 aa)
utp11Probable U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (249 aa)
mra1Ribosomal RNA small subunit methyltransferase mra1; S-adenosyl-L-methionine-dependent pseudouridine N(1)- methyltransferase that methylates the pseudouridine corresponding to position 1189 (Psi1189) in S.cerevisiae 18S rRNA. Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3- carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA. Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre- ribosomes (By similarity [...] (359 aa)
rrp6Exosome complex exonuclease rrp6; Nuclear-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export t [...] (777 aa)
bud2318S rRNA (guanine-N(7))-methyltransferase bud23; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity (By similarity). (268 aa)
ltv1Protein LTV1; Involved in protein transport. Non-ribosomal factor required for efficient nuclear export of the ribosomal 40S subunit. May participate in intracellular sorting of GAP1 out of the endosome (By similarity); Belongs to the LTV1 family. (386 aa)
rpl180160S ribosomal protein L18-A. (187 aa)
rrp43Exosome complex component rrp43; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplas [...] (270 aa)
rpl90160S ribosomal protein L9-A. (190 aa)
crb3Pre-rRNA-processing protein crb3/ipi3; Required for both pre-rRNA processing and heterochromatic gene silencing; Belongs to the WD repeat IPI3/WDR18 family. (446 aa)
rpp40Uncharacterized protein C6C3.09. (335 aa)
utp3Uncharacterized protein C3B8.09. (597 aa)
rpl180260S ribosomal protein L18-B. (187 aa)
rpl240160S ribosomal protein L24-A. (149 aa)
rpl360160S ribosomal protein L36-A. (99 aa)
rpl2960S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family. (61 aa)
rps60240S ribosomal protein S6-B. (239 aa)
pwp2Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family. (854 aa)
dhx37Putative ATP-dependent RNA helicase PB1A10.06c; Belongs to the DEAD box helicase family. DEAH subfamily. (1183 aa)
utp5U3 small nucleolar RNA-associated protein 5; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t- UTPs) (By similarity). (666 aa)
dbp8ATP-dependent RNA helicase dbp8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily. (453 aa)
rps50240S ribosomal protein S5-B. (203 aa)
rps40340S ribosomal protein S4-C; Belongs to the eukaryotic ribosomal protein eS4 family. (262 aa)
utp7Probable U3 small nucleolar RNA-associated protein 7; Involved in nucleolar processing of pre-18S ribosomal RNA. (520 aa)
rrp3ATP-dependent rRNA helicase rrp3; ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA. (465 aa)
rrp36rRNA biogenesis protein rrp36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity). (265 aa)
rpl100260S ribosomal protein L10-B. (221 aa)
rps80240S ribosomal protein S8-B. (200 aa)
rrp9Uncharacterized WD repeat-containing protein C2E1P5.05. (524 aa)
rps170240S ribosomal protein S17-B. (132 aa)
mtr3Exosome complex component mtr3; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm [...] (257 aa)
nop58Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family. (508 aa)
rio2Serine/threonine-protein kinase rio2; Required for the final endonucleolytic cleavage of 20S pre- rRNA at site D in the cytoplasm, converting it into the mature 18S rRNA. Involved in normal export of the pre-40S particles from the nucleus to the cytoplasm (By similarity); Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (344 aa)
rpl3160S ribosomal protein L31; Belongs to the eukaryotic ribosomal protein eL31 family. (113 aa)
ytm1Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (440 aa)
rpl150260S ribosomal protein L15-B. (201 aa)
rpl35A0160S ribosomal protein L33-B. (108 aa)
utp13Probable U3 small nucleolar RNA-associated protein 13; Involved in nucleolar processing of pre-18S ribosomal RNA. (777 aa)
rpl380160S ribosomal protein L38-1. (74 aa)
rps40240S ribosomal protein S4-B; Belongs to the eukaryotic ribosomal protein eS4 family. (262 aa)
rps260240S ribosomal protein S26-B. (119 aa)
rpl4260S ribosomal protein L42; Belongs to the eukaryotic ribosomal protein eL42 family. (106 aa)
nob120S-pre-rRNA D-site endonuclease nob1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm (By similarity). (388 aa)
rps150240S ribosomal protein S15-B. (154 aa)
grc3Polynucleotide 5'-hydroxyl-kinase grc3; Polynucleotide 5'-kinase required for both rRNA processing and heterochromatic gene silencing. (736 aa)
rpl210160S ribosomal protein L21-A. (160 aa)
rps00140S ribosomal protein S0-A; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (292 aa)
rpr2Ribonuclease P protein subunit rpr2; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 4 family. (107 aa)
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
Server load: low (18%) [HD]