(19 nodes) Selenocompound metabolism network (Streptomyces agglomeratus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OEJ61950.1	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
	OEJ62864.1	Thiol reductase thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
	OEJ58124.1	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1172 aa)
	OEJ58387.1	Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
	OEJ58604.1	Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
	BGM19_12790	Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (568 aa)
	OEJ59801.1	Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
	OEJ59835.1	Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
	OEJ59836.1	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (114 aa)
	metG	methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (539 aa)
	OEJ60192.1	Redoxin domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
	OEJ60556.1	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
	OEJ60889.1	Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
	OEJ60903.1	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (117 aa)
	OEJ60954.1	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
	OEJ61337.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
	OEJ62672.1	Thiol reductase thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
	OEJ61451.1	Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (447 aa)
	OEJ61452.1	Sulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)

Your Current Organism:

Streptomyces agglomeratus

NCBI taxonomy Id: 285458
Other names: S. agglomeratus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGM19_12790	OEJ58124.1	BGM19_12790	BGM19_09185	Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.804
BGM19_12790	OEJ59801.1	BGM19_12790	BGM19_19265	Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.797
BGM19_12790	OEJ60556.1	BGM19_12790	BGM19_23700	Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.676
BGM19_12790	OEJ60954.1	BGM19_12790	BGM19_26030	Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.457
OEJ58124.1	BGM19_12790	BGM19_09185	BGM19_12790	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.804
OEJ58124.1	OEJ58387.1	BGM19_09185	BGM19_10725	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.	0.762
OEJ58124.1	OEJ58604.1	BGM19_09185	BGM19_11985	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.762
OEJ58124.1	OEJ59801.1	BGM19_09185	BGM19_19265	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.983
OEJ58124.1	OEJ59836.1	BGM19_09185	BGM19_19455	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	0.692
OEJ58124.1	OEJ60556.1	BGM19_09185	BGM19_23700	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.983
OEJ58124.1	OEJ60889.1	BGM19_09185	BGM19_25640	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.692
OEJ58124.1	OEJ60903.1	BGM19_09185	BGM19_25710	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.	0.692
OEJ58124.1	OEJ60954.1	BGM19_09185	BGM19_26030	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.981
OEJ58124.1	OEJ61950.1	BGM19_09185	BGM19_31950	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.692
OEJ58124.1	OEJ62672.1	BGM19_09185	BGM19_36610	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Thiol reductase thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.692
OEJ58124.1	metG	BGM19_09185	BGM19_19935	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.826
OEJ58387.1	OEJ58124.1	BGM19_10725	BGM19_09185	Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.762
OEJ58387.1	OEJ58604.1	BGM19_10725	BGM19_11985	Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.	Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.887
OEJ58387.1	OEJ59801.1	BGM19_10725	BGM19_19265	Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.	Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.767
OEJ58387.1	OEJ59835.1	BGM19_10725	BGM19_19450	Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.	Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.905