STRINGSTRING
ybdK_1 ybdK_1 ybdK_2 ybdK_2 AOT57515.1 AOT57515.1 ybdK_3 ybdK_3 murI murI sbnA_1 sbnA_1 gpx2 gpx2 haeIIIM haeIIIM AOT58046.1 AOT58046.1 lvr lvr feaB feaB glnA2_1 glnA2_1 lldR lldR yhdG_2 yhdG_2 AOT58052.1 AOT58052.1 ald ald alaA_1 alaA_1 pepN_1 pepN_1 gltB_1 gltB_1 gltB_2 gltB_2 pepA pepA glnA glnA glnII glnII glnE glnE glnA2_2 glnA2_2 pepN_2 pepN_2 pepN_3 pepN_3 gdhB_1 gdhB_1 ahcY ahcY cbs cbs mutE mutE AOT59529.1 AOT59529.1 metC metC patB patB argA argA metB metB alaA_2 alaA_2 AOT60872.1 AOT60872.1 nrgA nrgA glnB glnB glnD glnD ybdK_5 ybdK_5 glsA glsA ggt ggt tyrB tyrB mmuM mmuM ybdK_6 ybdK_6 gdhA gdhA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ybdK_1Carboxylate-amine ligase YbdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (413 aa)
ybdK_2Carboxylate-amine ligase YbdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (364 aa)
AOT57515.1Hypothetical protein. (309 aa)
ybdK_3Carboxylate-amine ligase YbdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (363 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (258 aa)
sbnA_1Putative siderophore biosynthesis protein SbnA. (403 aa)
gpx2Hydroperoxy fatty acid reductase gpx2; Belongs to the glutathione peroxidase family. (162 aa)
haeIIIMModification methylase HaeIII. (452 aa)
AOT58046.1Hypothetical protein. (336 aa)
lvrLevodione reductase. (327 aa)
feaBPhenylacetaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (454 aa)
glnA2_1Putative glutamine synthetase 2. (458 aa)
lldRPutative L-lactate dehydrogenase operon regulatory protein. (254 aa)
yhdG_2Putative amino acid permease YhdG. (489 aa)
AOT58052.1Putative glutamine amidotransferase. (243 aa)
aldAlanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa)
alaA_1Glutamate-pyruvate aminotransferase AlaA. (403 aa)
pepN_1Aminopeptidase N. (833 aa)
gltB_1Glutamate synthase [NADPH] small chain. (486 aa)
gltB_2Glutamate synthase [NADPH] large chain. (1520 aa)
pepACytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (506 aa)
glnAGlutamine synthetase. (469 aa)
glnIIGlutamine synthetase 2. (343 aa)
glnEGlutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (995 aa)
glnA2_2Putative glutamine synthetase 2. (453 aa)
pepN_2Aminopeptidase N. (848 aa)
pepN_3Aminopeptidase N. (854 aa)
gdhB_1NAD-specific glutamate dehydrogenase. (1646 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (485 aa)
cbsPutative cystathionine beta-synthase. (461 aa)
mutEMethylaspartate mutase E chain. (457 aa)
AOT59529.1Methylaspartate mutase subunit S. (204 aa)
metCCystathionine beta-lyase. (380 aa)
patBCystathionine beta-lyase PatB. (389 aa)
argAAmino-acid acetyltransferase; Belongs to the acetyltransferase family. (234 aa)
metBCystathionine gamma-synthase. (384 aa)
alaA_2Glutamate-pyruvate aminotransferase AlaA. (403 aa)
AOT60872.1Ribosomal-protein-alanine N-acetyltransferase. (351 aa)
nrgAAmmonium transporter NrgA. (452 aa)
glnBNitrogen regulatory protein P-II. (112 aa)
glnDBifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (854 aa)
ybdK_5Carboxylate-amine ligase YbdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (366 aa)
glsAThermolabile glutaminase; Belongs to the glutaminase family. (305 aa)
ggtGamma-glutamyltranspeptidase precursor. (620 aa)
tyrBAromatic-amino-acid aminotransferase. (391 aa)
mmuMHomocysteine S-methyltransferase. (336 aa)
ybdK_6Carboxylate-amine ligase YbdK; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (374 aa)
gdhANADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa)
Your Current Organism:
Streptomyces rubrolavendulae
NCBI taxonomy Id: 285473
Other names: S. rubrolavendulae
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.