(55 nodes) Mixed, incl. Phosphopantetheine, and Siderophore metabolic process network (Streptomyces rubrolavendulae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOT57482.1	Cytochrome P450 107B1. (410 aa)
	srfAB_1	Surfactin synthase subunit 2. (506 aa)
	acpM	Meromycolate extension acyl carrier protein. (88 aa)
	AOT57686.1	Holo-(acyl carrier protein) synthase 2; Belongs to the P-Pant transferase superfamily. (234 aa)
	fabD	Malonyl CoA-acyl carrier protein transacylase. (307 aa)
	ppsB	Plipastatin synthase subunit B; Belongs to the ATP-dependent AMP-binding enzyme family. (527 aa)
	lgrD_1	Linear gramicidin synthase subunit D. (89 aa)
	mbtB	Phenyloxazoline synthase MbtB. (279 aa)
	ydfG	NADP-dependent 3-hydroxy acid dehydrogenase YdfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)
	acpS	Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (122 aa)
	tycC_1	Tyrocidine synthase 3. (614 aa)
	AOT61489.1	MbtH-like protein. (63 aa)
	lgrB_1	Linear gramicidin synthase subunit B. (462 aa)
	lgrB_2	Linear gramicidin synthase subunit B. (553 aa)
	lgrE_1	Linear gramicidin dehydrogenase LgrE. (262 aa)
	srfAA_1	Surfactin synthase subunit 1; Belongs to the ATP-dependent AMP-binding enzyme family. (1089 aa)
	tycC_2	Tyrocidine synthase 3. (1073 aa)
	tycC_3	Tyrocidine synthase 3. (2125 aa)
	lgrD_2	Linear gramicidin synthase subunit D. (4618 aa)
	lgrD_3	Linear gramicidin synthase subunit D. (2614 aa)
	AOT61524.1	MbtH-like protein. (69 aa)
	cypX	Pulcherriminic acid synthase; Belongs to the cytochrome P450 family. (411 aa)
	pksJ	Polyketide synthase PksJ. (3156 aa)
	pksN	Polyketide synthase PksN. (3208 aa)
	AOT61583.1	Phenolphthiocerol synthesis polyketide synthase type I Pks15/1. (2148 aa)
	bioF	8-amino-7-oxononanoate synthase. (1399 aa)
	srfAD	Surfactin synthase thioesterase subunit. (256 aa)
	AOT61593.1	Holo-(acyl carrier protein) synthase 2; Belongs to the P-Pant transferase superfamily. (248 aa)
	AOT61629.1	Hypothetical protein. (306 aa)
	ptlI_2	Pentalenene oxygenase; Belongs to the cytochrome P450 family. (517 aa)
	ptlI_3	Pentalenene oxygenase; Belongs to the cytochrome P450 family. (452 aa)
	lgrD_4	Linear gramicidin synthase subunit D. (315 aa)
	tycC_4	Tyrocidine synthase 3. (803 aa)
	npt	4'-phosphopantetheinyl transferase Npt; Belongs to the P-Pant transferase superfamily. (237 aa)
	ppsD	Plipastatin synthase subunit D. (1277 aa)
	srfAB_2	Surfactin synthase subunit 2. (86 aa)
	lgrE_2	Linear gramicidin dehydrogenase LgrE. (241 aa)
	lgrD_5	Linear gramicidin synthase subunit D; Belongs to the ATP-dependent AMP-binding enzyme family. (513 aa)
	dhbF_1	Dimodular nonribosomal peptide synthase. (2443 aa)
	tycC_5	Tyrocidine synthase 3. (2564 aa)
	tycA	Tyrocidine synthase 1; Belongs to the ATP-dependent AMP-binding enzyme family. (500 aa)
	AOT62435.1	MbtH-like protein. (72 aa)
	phzD	Putative isochorismatase. (218 aa)
	car	Carboxylic acid reductase. (1139 aa)
	linC_2	2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase. (254 aa)
	hsaD	4,5:9,10-diseco-3-hydroxy-5,9, 17-trioxoandrosta-1(10),2-diene-4-oate hydrolase. (330 aa)
	AOT62602.1	Acyl carrier protein. (78 aa)
	bacD_4	Alanine-anticapsin ligase BacD. (454 aa)
	srfAA_2	Surfactin synthase subunit 1. (496 aa)
	AOT62609.1	Cytochrome P450-terp. (412 aa)
	lgrB_3	Linear gramicidin synthase subunit B. (664 aa)
	lgrE_3	Linear gramicidin dehydrogenase LgrE. (242 aa)
	bacE	Putative bacilysin exporter BacE. (425 aa)
	dhbF_2	Dimodular nonribosomal peptide synthase. (1937 aa)
	AOT62619.1	MbtH-like protein. (69 aa)

Your Current Organism:

Streptomyces rubrolavendulae

NCBI taxonomy Id: 285473
Other names: S. rubrolavendulae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOT57482.1	AOT61583.1	A4G23_00271	A4G23_04471	Cytochrome P450 107B1.	Phenolphthiocerol synthesis polyketide synthase type I Pks15/1.	0.731
AOT57482.1	bioF	A4G23_00271	A4G23_04473	Cytochrome P450 107B1.	8-amino-7-oxononanoate synthase.	0.650
AOT57482.1	dhbF_1	A4G23_00271	A4G23_04866	Cytochrome P450 107B1.	Dimodular nonribosomal peptide synthase.	0.928
AOT57482.1	dhbF_2	A4G23_00271	A4G23_05512	Cytochrome P450 107B1.	Dimodular nonribosomal peptide synthase.	0.917
AOT57482.1	lgrB_2	A4G23_00271	A4G23_04382	Cytochrome P450 107B1.	Linear gramicidin synthase subunit B.	0.802
AOT57482.1	lgrD_1	A4G23_00271	A4G23_02053	Cytochrome P450 107B1.	Linear gramicidin synthase subunit D.	0.923
AOT57482.1	lgrD_2	A4G23_00271	A4G23_04410	Cytochrome P450 107B1.	Linear gramicidin synthase subunit D.	0.746
AOT57482.1	lgrD_5	A4G23_00271	A4G23_04856	Cytochrome P450 107B1.	Linear gramicidin synthase subunit D; Belongs to the ATP-dependent AMP-binding enzyme family.	0.779
AOT57482.1	pksJ	A4G23_00271	A4G23_04469	Cytochrome P450 107B1.	Polyketide synthase PksJ.	0.898
AOT57482.1	ppsD	A4G23_00271	A4G23_04733	Cytochrome P450 107B1.	Plipastatin synthase subunit D.	0.759
AOT57482.1	ptlI_2	A4G23_00271	A4G23_04518	Cytochrome P450 107B1.	Pentalenene oxygenase; Belongs to the cytochrome P450 family.	0.705
AOT57482.1	ptlI_3	A4G23_00271	A4G23_04519	Cytochrome P450 107B1.	Pentalenene oxygenase; Belongs to the cytochrome P450 family.	0.694
AOT57482.1	srfAA_1	A4G23_00271	A4G23_04384	Cytochrome P450 107B1.	Surfactin synthase subunit 1; Belongs to the ATP-dependent AMP-binding enzyme family.	0.917
AOT57482.1	srfAB_2	A4G23_00271	A4G23_04853	Cytochrome P450 107B1.	Surfactin synthase subunit 2.	0.985
AOT57482.1	tycC_3	A4G23_00271	A4G23_04390	Cytochrome P450 107B1.	Tyrocidine synthase 3.	0.987
AOT57482.1	tycC_4	A4G23_00271	A4G23_04550	Cytochrome P450 107B1.	Tyrocidine synthase 3.	0.738
AOT57482.1	tycC_5	A4G23_00271	A4G23_05326	Cytochrome P450 107B1.	Tyrocidine synthase 3.	0.779
AOT57686.1	AOT61489.1	A4G23_00476	A4G23_04377	Holo-(acyl carrier protein) synthase 2; Belongs to the P-Pant transferase superfamily.	MbtH-like protein.	0.448
AOT57686.1	AOT61524.1	A4G23_00476	A4G23_04412	Holo-(acyl carrier protein) synthase 2; Belongs to the P-Pant transferase superfamily.	MbtH-like protein.	0.404
AOT57686.1	AOT61583.1	A4G23_00476	A4G23_04471	Holo-(acyl carrier protein) synthase 2; Belongs to the P-Pant transferase superfamily.	Phenolphthiocerol synthesis polyketide synthase type I Pks15/1.	0.947