STRINGSTRING
polX_2 polX_2 mug mug ung_2 ung_2 ypcP ypcP nfo nfo exoA exoA AOT61050.1 AOT61050.1 AOT61051.1 AOT61051.1 ykoV ykoV ligA ligA fpg1 fpg1 xthA xthA AOT62104.1 AOT62104.1 ykoU ykoU fpg2 fpg2 lig lig
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
polX_2DNA polymerase/3'-5' exonuclease PolX. (577 aa)
mugG/U mismatch-specific DNA glycosylase. (187 aa)
ung_2Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (227 aa)
ypcP5'-3' exonuclease. (310 aa)
nfoPutative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (358 aa)
exoAExodeoxyribonuclease. (281 aa)
AOT61050.1Putative DNA ligase-like protein. (306 aa)
AOT61051.1Putative DNA ligase-like protein. (328 aa)
ykoVPutative DNA repair protein YkoV; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (419 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (734 aa)
fpg1Formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (290 aa)
xthAExodeoxyribonuclease III. (259 aa)
AOT62104.1Putative DNA ligase-like protein. (362 aa)
ykoUPutative ATP-dependent DNA ligase YkoU. (331 aa)
fpg2Putative formamidopyrimidine-DNA glycosylase-like protein; Belongs to the FPG family. (286 aa)
ligPutative DNA ligase-like protein; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (518 aa)
Your Current Organism:
Streptomyces rubrolavendulae
NCBI taxonomy Id: 285473
Other names: S. rubrolavendulae
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