(5 nodes) RecQ zinc-binding, and DNA topoisomerase type I (single strand cut, ATP-independent) activity network (Streptomyces rubrolavendulae)

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Your Input:
	AOT57435.1	Eukaryotic DNA topoisomerase I, catalytic core. (342 aa)
	recQ_1	ATP-dependent DNA helicase RecQ. (567 aa)
	topA	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (954 aa)
	recQ_2	ATP-dependent DNA helicase RecQ. (720 aa)
	recQ_3	ATP-dependent DNA helicase RecQ. (613 aa)

Your Current Organism:

Streptomyces rubrolavendulae

NCBI taxonomy Id: 285473
Other names: S. rubrolavendulae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOT57435.1	recQ_1	A4G23_00222	A4G23_00325	Eukaryotic DNA topoisomerase I, catalytic core.	ATP-dependent DNA helicase RecQ.	0.724
AOT57435.1	recQ_2	A4G23_00222	A4G23_04321	Eukaryotic DNA topoisomerase I, catalytic core.	ATP-dependent DNA helicase RecQ.	0.724
AOT57435.1	recQ_3	A4G23_00222	A4G23_04637	Eukaryotic DNA topoisomerase I, catalytic core.	ATP-dependent DNA helicase RecQ.	0.724
AOT57435.1	topA	A4G23_00222	A4G23_03042	Eukaryotic DNA topoisomerase I, catalytic core.	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.532
recQ_1	AOT57435.1	A4G23_00325	A4G23_00222	ATP-dependent DNA helicase RecQ.	Eukaryotic DNA topoisomerase I, catalytic core.	0.724
recQ_1	recQ_2	A4G23_00325	A4G23_04321	ATP-dependent DNA helicase RecQ.	ATP-dependent DNA helicase RecQ.	0.924
recQ_1	recQ_3	A4G23_00325	A4G23_04637	ATP-dependent DNA helicase RecQ.	ATP-dependent DNA helicase RecQ.	0.921
recQ_1	topA	A4G23_00325	A4G23_03042	ATP-dependent DNA helicase RecQ.	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.968
recQ_2	AOT57435.1	A4G23_04321	A4G23_00222	ATP-dependent DNA helicase RecQ.	Eukaryotic DNA topoisomerase I, catalytic core.	0.724
recQ_2	recQ_1	A4G23_04321	A4G23_00325	ATP-dependent DNA helicase RecQ.	ATP-dependent DNA helicase RecQ.	0.924
recQ_2	recQ_3	A4G23_04321	A4G23_04637	ATP-dependent DNA helicase RecQ.	ATP-dependent DNA helicase RecQ.	0.924
recQ_2	topA	A4G23_04321	A4G23_03042	ATP-dependent DNA helicase RecQ.	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.968
recQ_3	AOT57435.1	A4G23_04637	A4G23_00222	ATP-dependent DNA helicase RecQ.	Eukaryotic DNA topoisomerase I, catalytic core.	0.724
recQ_3	recQ_1	A4G23_04637	A4G23_00325	ATP-dependent DNA helicase RecQ.	ATP-dependent DNA helicase RecQ.	0.921
recQ_3	recQ_2	A4G23_04637	A4G23_04321	ATP-dependent DNA helicase RecQ.	ATP-dependent DNA helicase RecQ.	0.924
recQ_3	topA	A4G23_04637	A4G23_03042	ATP-dependent DNA helicase RecQ.	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.968
topA	AOT57435.1	A4G23_03042	A4G23_00222	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	Eukaryotic DNA topoisomerase I, catalytic core.	0.532
topA	recQ_1	A4G23_03042	A4G23_00325	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	ATP-dependent DNA helicase RecQ.	0.968
topA	recQ_2	A4G23_03042	A4G23_04321	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	ATP-dependent DNA helicase RecQ.	0.968
topA	recQ_3	A4G23_03042	A4G23_04637	DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	ATP-dependent DNA helicase RecQ.	0.968