(68 nodes) Carbohydrate catabolic process network (Streptomyces rubrolavendulae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	axeA	Cephalosporin-C deacetylase. (323 aa)
	celE	Endoglucanase E-5 precursor; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (411 aa)
	gbpA	GlcNAc-binding protein A precursor. (279 aa)
	dhaK	PTS-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK. (330 aa)
	dhaM	PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit DhaM. (154 aa)
	AOT57484.1	Endoglucanase E1 precursor. (743 aa)
	iolD	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family. (628 aa)
	csxA	Exo-beta-D-glucosaminidase precursor. (829 aa)
	abfB_1	Extracellular exo-alpha-L-arabinofuranosidase precursor. (489 aa)
	xynB_1	Beta-xylosidase; Belongs to the glycosyl hydrolase 43 family. (480 aa)
	pel_1	Pectate trisaccharide-lyase precursor. (520 aa)
	xlnA	Endo-1,4-beta-xylanase A precursor. (478 aa)
	araD	L-ribulose-5-phosphate 4-epimerase. (237 aa)
	araA	L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (511 aa)
	araB	Ribulokinase. (575 aa)
	galT_1	Galactose-1-phosphate uridylyltransferase. (368 aa)
	pfp_1	Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
	yceM	Putative oxidoreductase YceM. (302 aa)
	rpe	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
	glpK	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (510 aa)
	xylB_1	Xylulose kinase. (507 aa)
	AOT58200.1	Trehalase. (600 aa)
	AOT58259.1	Trehalase. (594 aa)
	fucA	L-fuculose phosphate aldolase. (237 aa)
	pel_2	Pectate lyase precursor. (462 aa)
	xynB_2	Beta-xylosidase; Belongs to the glycosyl hydrolase 43 family. (553 aa)
	AOT58300.1	Hypothetical protein. (291 aa)
	AOT58301.1	Oxidoreductase family, NAD-binding Rossmann fold. (419 aa)
	pgi	Glucose-6-phosphate isomerase; Belongs to the GPI family. (539 aa)
	tpiA	Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa)
	pgk	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa)
	gap2	Glyceraldehyde-3-phosphate dehydrogenase 2; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
	pyk_1	Pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa)
	glkA_1	Glucokinase. (313 aa)
	aceE_1	Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (897 aa)
	afr	1,5-anhydro-D-fructose reductase. (328 aa)
	aceE_2	Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa)
	xylB_2	Xylulose kinase; Belongs to the FGGY kinase family. (479 aa)
	ligC	4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase. (337 aa)
	yhhX	Putative oxidoreductase YhhX. (383 aa)
	pelX	Pectate disaccharide-lyase precursor. (530 aa)
	cbhB_1	Exoglucanase B precursor. (973 aa)
	cbhA	Exoglucanase A precursor; Belongs to the glycosyl hydrolase family 6. (577 aa)
	yvaA	Putative oxidoreductase YvaA. (417 aa)
	AOT59193.1	Bifunctional phosphoglucose/phosphomannose isomerase. (379 aa)
	eno	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
	galT_2	Galactose-1-phosphate uridylyltransferase. (349 aa)
	fbaA	Putative fructose-bisphosphate aldolase. (287 aa)
	gpmA	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (253 aa)
	pdhC	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. (488 aa)
	bkdB_2	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (457 aa)
	fba	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
	AOT60611.1	Metal-dependent hydrolase. (288 aa)
	deoC	Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (316 aa)
	chtA	Chitinase 63 precursor. (620 aa)
	pyk_2	Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa)
	pfp_2	Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
	glgX_1	Glycogen debranching enzyme; Belongs to the glycosyl hydrolase 13 family. (754 aa)
	AOT61325.1	Hypothetical protein. (282 aa)
	AOT61565.1	Glucan endo-1,3-beta-glucosidase precursor. (591 aa)
	cbhB_3	Exoglucanase B precursor. (1112 aa)
	cel1	Cellulase 1 precursor. (882 aa)
	glgX_2	Glycogen debranching enzyme; Belongs to the glycosyl hydrolase 13 family. (746 aa)
	idhA	Inositol 2-dehydrogenase. (333 aa)
	AOT61980.1	Metal-dependent hydrolase. (210 aa)
	AOT62059.1	Metal-dependent hydrolase. (387 aa)
	AOT62061.1	Metal-dependent hydrolase. (255 aa)
	AOT62158.1	Metal-dependent hydrolase. (399 aa)

Your Current Organism:

Streptomyces rubrolavendulae

NCBI taxonomy Id: 285473
Other names: S. rubrolavendulae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOT57484.1	abfB_1	A4G23_00273	A4G23_00442	Endoglucanase E1 precursor.	Extracellular exo-alpha-L-arabinofuranosidase precursor.	0.573
AOT57484.1	cbhA	A4G23_00273	A4G23_01863	Endoglucanase E1 precursor.	Exoglucanase A precursor; Belongs to the glycosyl hydrolase family 6.	0.978
AOT57484.1	cbhB_1	A4G23_00273	A4G23_01861	Endoglucanase E1 precursor.	Exoglucanase B precursor.	0.754
AOT57484.1	cel1	A4G23_00273	A4G23_00036	Endoglucanase E1 precursor.	Cellulase 1 precursor.	0.973
AOT57484.1	celE	A4G23_00273	A4G23_05286	Endoglucanase E1 precursor.	Endoglucanase E-5 precursor; Belongs to the glycosyl hydrolase 5 (cellulase A) family.	0.935
AOT57484.1	gbpA	A4G23_00273	A4G23_00110	Endoglucanase E1 precursor.	GlcNAc-binding protein A precursor.	0.423
AOT57484.1	pelX	A4G23_00273	A4G23_01796	Endoglucanase E1 precursor.	Pectate disaccharide-lyase precursor.	0.545
AOT57484.1	pel_1	A4G23_00273	A4G23_00035	Endoglucanase E1 precursor.	Pectate trisaccharide-lyase precursor.	0.465
AOT57484.1	xlnA	A4G23_00273	A4G23_00449	Endoglucanase E1 precursor.	Endo-1,4-beta-xylanase A precursor.	0.639
AOT58300.1	AOT58301.1	A4G23_01109	A4G23_01110	Hypothetical protein.	Oxidoreductase family, NAD-binding Rossmann fold.	0.997
AOT58300.1	cbhA	A4G23_01109	A4G23_01863	Hypothetical protein.	Exoglucanase A precursor; Belongs to the glycosyl hydrolase family 6.	0.504
AOT58300.1	cbhB_1	A4G23_01109	A4G23_01861	Hypothetical protein.	Exoglucanase B precursor.	0.486
AOT58300.1	iolD	A4G23_01109	A4G23_00276	Hypothetical protein.	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family.	0.604
AOT58300.1	pel_1	A4G23_01109	A4G23_00035	Hypothetical protein.	Pectate trisaccharide-lyase precursor.	0.602
AOT58300.1	pel_2	A4G23_01109	A4G23_01105	Hypothetical protein.	Pectate lyase precursor.	0.813
AOT58300.1	xynB_2	A4G23_01109	A4G23_01108	Hypothetical protein.	Beta-xylosidase; Belongs to the glycosyl hydrolase 43 family.	0.904
AOT58300.1	yhhX	A4G23_01109	A4G23_01791	Hypothetical protein.	Putative oxidoreductase YhhX.	0.673
AOT58301.1	AOT58300.1	A4G23_01110	A4G23_01109	Oxidoreductase family, NAD-binding Rossmann fold.	Hypothetical protein.	0.997
AOT58301.1	axeA	A4G23_01110	A4G23_05285	Oxidoreductase family, NAD-binding Rossmann fold.	Cephalosporin-C deacetylase.	0.406
AOT58301.1	iolD	A4G23_01110	A4G23_00276	Oxidoreductase family, NAD-binding Rossmann fold.	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family.	0.667