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leuA_2 leuA_2 leuA_1 leuA_1 yngG yngG AOT60663.1 AOT60663.1 leuA_3 leuA_3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
leuA_22-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (535 aa)
leuA_12-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (589 aa)
yngGHydroxymethylglutaryl-CoA lyase YngG. (311 aa)
AOT60663.14-hydroxy-2-oxovalerate aldolase. (340 aa)
leuA_32-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (391 aa)
Your Current Organism:
Streptomyces rubrolavendulae
NCBI taxonomy Id: 285473
Other names: S. rubrolavendulae
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