(27 nodes) Helicase superfamily 1/2, ATP-binding domain network (Streptomyces rubrolavendulae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	cshA	DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family. (676 aa)
	srmB	ATP-dependent RNA helicase SrmB. (830 aa)
	rhlE_2	ATP-dependent RNA helicase RhlE. (497 aa)
	hrpB_2	ATP-dependent RNA helicase HrpB. (1319 aa)
	rhlE_1	ATP-dependent RNA helicase RhlE. (749 aa)
	AOT58061.1	Ski2-like helicase. (942 aa)
	AOT57759.1	Hypothetical protein; SNF2 family N-terminal domain. (608 aa)
	AOT57705.1	Ski2-like helicase. (837 aa)
	recQ_1	ATP-dependent DNA helicase RecQ. (567 aa)
	uvrB	UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (722 aa)
	mfd	Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1176 aa)
	secA	Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (936 aa)
	rgy	Reverse gyrase. (562 aa)
	hsdR_2	Type I restriction enzyme EcoR124II R protein. (1185 aa)
	hsdR_1	Type-1 restriction enzyme R protein; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1032 aa)
	hrpB_1	ATP-dependent RNA helicase HrpB. (897 aa)
	AOT58374.1	ATP-dependent helicase HepA. (989 aa)
	AOT62537.1	ATP-dependent helicase HepA. (977 aa)
	rhlE_4	ATP-dependent RNA helicase RhlE. (475 aa)
	recQ_3	ATP-dependent DNA helicase RecQ. (613 aa)
	cas3	CRISPR-associated nuclease/helicase Cas3. (1594 aa)
	AOT59558.1	Hypothetical protein; Helicase conserved C-terminal domain. (547 aa)
	rhlE_3	ATP-dependent RNA helicase RhlE. (499 aa)
	recQ_2	ATP-dependent DNA helicase RecQ. (720 aa)
	dinG	Putative ATP-dependent helicase DinG. (655 aa)
	AOT61390.1	Putative ATP-dependent helicase Lhr. (1544 aa)
	recG	ATP-dependent DNA helicase RecG. (762 aa)

Your Current Organism:

Streptomyces rubrolavendulae

NCBI taxonomy Id: 285473
Other names: S. rubrolavendulae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOT57705.1	hrpB_2	A4G23_00495	A4G23_02612	Ski2-like helicase.	ATP-dependent RNA helicase HrpB.	0.509
AOT57759.1	AOT59558.1	A4G23_00549	A4G23_02400	Hypothetical protein; SNF2 family N-terminal domain.	Hypothetical protein; Helicase conserved C-terminal domain.	0.536
AOT57759.1	cshA	A4G23_00549	A4G23_03778	Hypothetical protein; SNF2 family N-terminal domain.	DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family.	0.429
AOT57759.1	dinG	A4G23_00549	A4G23_04309	Hypothetical protein; SNF2 family N-terminal domain.	Putative ATP-dependent helicase DinG.	0.779
AOT57759.1	recQ_1	A4G23_00549	A4G23_00325	Hypothetical protein; SNF2 family N-terminal domain.	ATP-dependent DNA helicase RecQ.	0.545
AOT57759.1	recQ_2	A4G23_00549	A4G23_04321	Hypothetical protein; SNF2 family N-terminal domain.	ATP-dependent DNA helicase RecQ.	0.551
AOT57759.1	recQ_3	A4G23_00549	A4G23_04637	Hypothetical protein; SNF2 family N-terminal domain.	ATP-dependent DNA helicase RecQ.	0.579
AOT57759.1	rgy	A4G23_00549	A4G23_01951	Hypothetical protein; SNF2 family N-terminal domain.	Reverse gyrase.	0.536
AOT57759.1	rhlE_1	A4G23_00549	A4G23_02600	Hypothetical protein; SNF2 family N-terminal domain.	ATP-dependent RNA helicase RhlE.	0.429
AOT57759.1	rhlE_2	A4G23_00549	A4G23_02890	Hypothetical protein; SNF2 family N-terminal domain.	ATP-dependent RNA helicase RhlE.	0.429
AOT57759.1	rhlE_3	A4G23_00549	A4G23_04406	Hypothetical protein; SNF2 family N-terminal domain.	ATP-dependent RNA helicase RhlE.	0.429
AOT57759.1	rhlE_4	A4G23_00549	A4G23_05430	Hypothetical protein; SNF2 family N-terminal domain.	ATP-dependent RNA helicase RhlE.	0.429
AOT58374.1	AOT59558.1	A4G23_01183	A4G23_02400	ATP-dependent helicase HepA.	Hypothetical protein; Helicase conserved C-terminal domain.	0.536
AOT58374.1	cshA	A4G23_01183	A4G23_03778	ATP-dependent helicase HepA.	DEAD-box ATP-dependent RNA helicase CshA; Belongs to the DEAD box helicase family.	0.438
AOT58374.1	dinG	A4G23_01183	A4G23_04309	ATP-dependent helicase HepA.	Putative ATP-dependent helicase DinG.	0.814
AOT58374.1	recQ_1	A4G23_01183	A4G23_00325	ATP-dependent helicase HepA.	ATP-dependent DNA helicase RecQ.	0.576
AOT58374.1	recQ_2	A4G23_01183	A4G23_04321	ATP-dependent helicase HepA.	ATP-dependent DNA helicase RecQ.	0.562
AOT58374.1	recQ_3	A4G23_01183	A4G23_04637	ATP-dependent helicase HepA.	ATP-dependent DNA helicase RecQ.	0.556
AOT58374.1	rgy	A4G23_01183	A4G23_01951	ATP-dependent helicase HepA.	Reverse gyrase.	0.536
AOT58374.1	rhlE_1	A4G23_01183	A4G23_02600	ATP-dependent helicase HepA.	ATP-dependent RNA helicase RhlE.	0.429