(30 nodes) Butanoate metabolism network (Streptomyces rubrolavendulae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gabD1	Succinate-semialdehyde dehydrogenase [NADP(+)] 1. (463 aa)
	acsA_1	Acetyl-coenzyme A synthetase. (670 aa)
	fadB2_1	3-hydroxybutyryl-CoA dehydrogenase. (286 aa)
	ilvB	Acetolactate synthase large subunit; Belongs to the TPP enzyme family. (562 aa)
	yngG	Hydroxymethylglutaryl-CoA lyase YngG. (311 aa)
	thlA	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
	fadB_2	Putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (244 aa)
	paaH	3-hydroxyadipyl-CoA dehydrogenase. (539 aa)
	korB	2-oxoglutarate oxidoreductase subunit KorB. (350 aa)
	korA	2-oxoglutarate oxidoreductase subunit KorA. (741 aa)
	gabD2	Putative succinate-semialdehyde dehydrogenase [NADP(+)] 2; Belongs to the aldehyde dehydrogenase family. (589 aa)
	sdhB	Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (252 aa)
	sdhA	Succinate dehydrogenase flavoprotein subunit. (584 aa)
	AOT60647.1	Succinate dehydrogenase cytochrome b556 small membrane subunit. (159 aa)
	AOT60648.1	Succinate dehydrogenase/Fumarate reductase transmembrane subunit. (126 aa)
	fadB2_2	3-hydroxybutyryl-CoA dehydrogenase. (282 aa)
	AOT61109.1	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
	ilvB1	Acetolactate synthase large subunit IlvB1. (617 aa)
	ilvH	Acetolactate synthase small subunit. (174 aa)
	bioK_3	L-Lysine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
	gabT	4-aminobutyrate aminotransferase GabT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
	argD_2	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa)
	ccr	Crotonyl-CoA reductase. (445 aa)
	mmgB	Putative 3-hydroxybutyryl-CoA dehydrogenase. (594 aa)
	fadA	Putative acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
	fadJ_2	Fatty acid oxidation complex subunit alpha. (726 aa)
	AOT62337.1	Succinate dehydrogenase/Fumarate reductase transmembrane subunit. (207 aa)
	frdA	Fumarate reductase flavoprotein subunit. (649 aa)
	frdB	Fumarate reductase iron-sulfur subunit. (248 aa)
	bdhA	D-beta-hydroxybutyrate dehydrogenase. (263 aa)

Your Current Organism:

Streptomyces rubrolavendulae

NCBI taxonomy Id: 285473
Other names: S. rubrolavendulae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOT60647.1	AOT60648.1	A4G23_03522	A4G23_03523	Succinate dehydrogenase cytochrome b556 small membrane subunit.	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	0.999
AOT60647.1	AOT62337.1	A4G23_03522	A4G23_05233	Succinate dehydrogenase cytochrome b556 small membrane subunit.	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	0.900
AOT60647.1	frdA	A4G23_03522	A4G23_05234	Succinate dehydrogenase cytochrome b556 small membrane subunit.	Fumarate reductase flavoprotein subunit.	0.997
AOT60647.1	frdB	A4G23_03522	A4G23_05235	Succinate dehydrogenase cytochrome b556 small membrane subunit.	Fumarate reductase iron-sulfur subunit.	0.997
AOT60647.1	gabD1	A4G23_03522	A4G23_00148	Succinate dehydrogenase cytochrome b556 small membrane subunit.	Succinate-semialdehyde dehydrogenase [NADP(+)] 1.	0.903
AOT60647.1	gabD2	A4G23_03522	A4G23_03452	Succinate dehydrogenase cytochrome b556 small membrane subunit.	Putative succinate-semialdehyde dehydrogenase [NADP(+)] 2; Belongs to the aldehyde dehydrogenase family.	0.903
AOT60647.1	sdhA	A4G23_03522	A4G23_03521	Succinate dehydrogenase cytochrome b556 small membrane subunit.	Succinate dehydrogenase flavoprotein subunit.	0.999
AOT60647.1	sdhB	A4G23_03522	A4G23_03520	Succinate dehydrogenase cytochrome b556 small membrane subunit.	Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.999
AOT60648.1	AOT60647.1	A4G23_03523	A4G23_03522	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	Succinate dehydrogenase cytochrome b556 small membrane subunit.	0.999
AOT60648.1	AOT62337.1	A4G23_03523	A4G23_05233	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	0.900
AOT60648.1	acsA_1	A4G23_03523	A4G23_00643	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	Acetyl-coenzyme A synthetase.	0.413
AOT60648.1	fadJ_2	A4G23_03523	A4G23_05010	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	Fatty acid oxidation complex subunit alpha.	0.531
AOT60648.1	frdA	A4G23_03523	A4G23_05234	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	Fumarate reductase flavoprotein subunit.	0.999
AOT60648.1	frdB	A4G23_03523	A4G23_05235	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	Fumarate reductase iron-sulfur subunit.	0.999
AOT60648.1	gabD1	A4G23_03523	A4G23_00148	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	Succinate-semialdehyde dehydrogenase [NADP(+)] 1.	0.904
AOT60648.1	gabD2	A4G23_03523	A4G23_03452	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	Putative succinate-semialdehyde dehydrogenase [NADP(+)] 2; Belongs to the aldehyde dehydrogenase family.	0.904
AOT60648.1	korA	A4G23_03523	A4G23_03280	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	2-oxoglutarate oxidoreductase subunit KorA.	0.851
AOT60648.1	korB	A4G23_03523	A4G23_03279	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	2-oxoglutarate oxidoreductase subunit KorB.	0.429
AOT60648.1	sdhA	A4G23_03523	A4G23_03521	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	Succinate dehydrogenase flavoprotein subunit.	0.999
AOT60648.1	sdhB	A4G23_03523	A4G23_03520	Succinate dehydrogenase/Fumarate reductase transmembrane subunit.	Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.	0.999