(58 nodes) Rossmann-like alpha/beta/alpha sandwich fold network (Azospirillum oryzae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	SMF47316.1	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase. (437 aa)
	tyrS-2	tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (422 aa)
	nadD	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (213 aa)
	SMF82131.1	NAD+ synthase; Belongs to the NAD synthetase family. (555 aa)
	gltX-2	glutamyl-tRNA synthetase /glutamate--tRNA(Gln) ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (447 aa)
	cysS	cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (459 aa)
	mnmA	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (387 aa)
	SMF79715.1	Deoxyribodipyrimidine photo-lyase; Belongs to the DNA photolyase family. (489 aa)
	metG	methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (516 aa)
	SMF78967.1	Uncharacterized SAM-binding protein YcdF, DUF218 family. (264 aa)
	guaA	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (522 aa)
	SMF77198.1	Electron transfer flavoprotein alpha subunit apoprotein. (308 aa)
	SMF77192.1	Electron transfer flavoprotein beta subunit. (249 aa)
	coaD	Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (187 aa)
	valS	valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (882 aa)
	gltX	glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (468 aa)
	tilS	tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (448 aa)
	SMF71402.1	Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. (236 aa)
	SMF71393.1	Sulfate adenylyltransferase subunit 2. (265 aa)
	ileS	Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (943 aa)
	SMF69390.1	Electron transfer flavoprotein alpha subunit apoprotein. (359 aa)
	SMF69387.1	Electron transfer flavoprotein beta subunit. (283 aa)
	SMF69243.1	Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (313 aa)
	queC	preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (238 aa)
	tyrS	tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (415 aa)
	SMF65525.1	Electron transfer flavoprotein alpha subunit apoprotein. (308 aa)
	SMF65517.1	Electron transfer flavoprotein beta subunit. (249 aa)
	leuS	leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (856 aa)
	nadE-2	NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (681 aa)
	SMF48985.1	Two-component system, OmpR family, sensor histidine kinase KdpD. (903 aa)
	SMF43553.1	Asparagine synthase (glutamine-hydrolysing). (641 aa)
	SMF91142.1	Uncharacterized SAM-binding protein YcdF, DUF218 family. (213 aa)
	SMF21192.1	Nucleotide-binding universal stress protein, UspA family. (284 aa)
	SMF21200.1	Nucleotide-binding universal stress protein, UspA family. (364 aa)
	SMF28281.1	Asparagine synthase (glutamine-hydrolysing). (591 aa)
	nadE	NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (334 aa)
	SMF28831.1	Asparagine synthase (glutamine-hydrolysing). (683 aa)
	argS	arginyl-tRNA synthetase. (586 aa)
	panC	Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (293 aa)
	SMF34047.1	7-cyano-7-deazaguanine synthase (queuosine biosynthesis). (458 aa)
	SMF36234.1	Electron transfer flavoprotein beta subunit. (249 aa)
	SMF36248.1	Electron transfer flavoprotein alpha subunit apoprotein. (308 aa)
	cysD	Sulfate adenylyltransferase subunit 2. (333 aa)
	SMF42196.1	Asparagine synthase (glutamine-hydrolyzing). (569 aa)
	SMF90023.1	Electron transfer flavoprotein beta subunit. (253 aa)
	SMF90019.1	Electron transfer flavoprotein alpha subunit apoprotein. (308 aa)
	SMF88906.1	Electron transfer flavoprotein beta subunit. (260 aa)
	SMF88903.1	Electron transfer flavoprotein alpha subunit apoprotein. (410 aa)
	SMF87038.1	Electron transfer flavoprotein alpha subunit apoprotein. (308 aa)
	SMF87035.1	Electron transfer flavoprotein beta subunit. (249 aa)
	SMF86523.1	Electron transfer flavoprotein alpha subunit apoprotein. (312 aa)
	SMF86520.1	Electron transfer flavoprotein beta subunit. (249 aa)
	SMF84661.1	Universal stress protein family protein. (169 aa)
	trpS	tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (332 aa)
	argG	Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (411 aa)
	lysS	lysyl-tRNA synthetase, class I; Belongs to the class-I aminoacyl-tRNA synthetase family. (522 aa)
	SMF83542.1	glutamyl-Q tRNA(Asp) synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (287 aa)
	hldE	D-alpha,beta-D-heptose 7-phosphate 1-kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (481 aa)

Your Current Organism:

Azospirillum oryzae

NCBI taxonomy Id: 286727
Other names: A. oryzae, Azospirillum oryzae Xie and Yokota 2005, CCTCC AB204051, IAM 15130, JCM 21588, NBRC 102291, strain COC8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SMF21192.1	SMF21200.1	SAMN02982917_0957	SAMN02982917_0958	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.687
SMF21200.1	SMF21192.1	SAMN02982917_0958	SAMN02982917_0957	Nucleotide-binding universal stress protein, UspA family.	Nucleotide-binding universal stress protein, UspA family.	0.687
SMF28281.1	SMF28831.1	SAMN02982917_1267	SAMN02982917_1317	Asparagine synthase (glutamine-hydrolysing).	Asparagine synthase (glutamine-hydrolysing).	0.863
SMF28281.1	SMF43553.1	SAMN02982917_1267	SAMN02982917_2233	Asparagine synthase (glutamine-hydrolysing).	Asparagine synthase (glutamine-hydrolysing).	0.857
SMF28281.1	SMF82131.1	SAMN02982917_1267	SAMN02982917_5292	Asparagine synthase (glutamine-hydrolysing).	NAD+ synthase; Belongs to the NAD synthetase family.	0.442
SMF28281.1	argG	SAMN02982917_1267	SAMN02982917_5709	Asparagine synthase (glutamine-hydrolysing).	Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.	0.858
SMF28281.1	guaA	SAMN02982917_1267	SAMN02982917_4753	Asparagine synthase (glutamine-hydrolysing).	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	0.442
SMF28281.1	nadE-2	SAMN02982917_1267	SAMN02982917_2627	Asparagine synthase (glutamine-hydrolysing).	NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.442
SMF28831.1	SMF28281.1	SAMN02982917_1317	SAMN02982917_1267	Asparagine synthase (glutamine-hydrolysing).	Asparagine synthase (glutamine-hydrolysing).	0.863
SMF28831.1	SMF43553.1	SAMN02982917_1317	SAMN02982917_2233	Asparagine synthase (glutamine-hydrolysing).	Asparagine synthase (glutamine-hydrolysing).	0.862
SMF28831.1	SMF82131.1	SAMN02982917_1317	SAMN02982917_5292	Asparagine synthase (glutamine-hydrolysing).	NAD+ synthase; Belongs to the NAD synthetase family.	0.442
SMF28831.1	argG	SAMN02982917_1317	SAMN02982917_5709	Asparagine synthase (glutamine-hydrolysing).	Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.	0.858
SMF28831.1	guaA	SAMN02982917_1317	SAMN02982917_4753	Asparagine synthase (glutamine-hydrolysing).	GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.	0.442
SMF28831.1	nadE	SAMN02982917_1317	SAMN02982917_1316	Asparagine synthase (glutamine-hydrolysing).	NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.759
SMF28831.1	nadE-2	SAMN02982917_1317	SAMN02982917_2627	Asparagine synthase (glutamine-hydrolysing).	NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.442
SMF36234.1	SMF36248.1	SAMN02982917_1853	SAMN02982917_1854	Electron transfer flavoprotein beta subunit.	Electron transfer flavoprotein alpha subunit apoprotein.	0.995
SMF36234.1	SMF65525.1	SAMN02982917_1853	SAMN02982917_3414	Electron transfer flavoprotein beta subunit.	Electron transfer flavoprotein alpha subunit apoprotein.	0.981
SMF36234.1	SMF69390.1	SAMN02982917_1853	SAMN02982917_3780	Electron transfer flavoprotein beta subunit.	Electron transfer flavoprotein alpha subunit apoprotein.	0.947
SMF36234.1	SMF77198.1	SAMN02982917_1853	SAMN02982917_4660	Electron transfer flavoprotein beta subunit.	Electron transfer flavoprotein alpha subunit apoprotein.	0.981
SMF36234.1	SMF86523.1	SAMN02982917_1853	SAMN02982917_5985	Electron transfer flavoprotein beta subunit.	Electron transfer flavoprotein alpha subunit apoprotein.	0.981