(5 nodes) Mixed, incl. TSG101 and ALIX binding domain of CEP55, and Positive regulation of mitotic DNA damage checkpoint network (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	melk	Non-specific serine/threonine protein kinase. (680 aa)
	nusap1	Nucleolar and spindle associated protein 1. (449 aa)
	cep55	Centrosomal protein 55 like. (533 aa)
	kif4a	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1243 aa)
	pbk	PDZ binding kinase. (352 aa)

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cep55	kif4a	ENSCVAP00000019303	ENSCVAP00000024864	Centrosomal protein 55 like.	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.843
cep55	melk	ENSCVAP00000019303	ENSCVAP00000016448	Centrosomal protein 55 like.	Non-specific serine/threonine protein kinase.	0.841
cep55	nusap1	ENSCVAP00000019303	ENSCVAP00000018926	Centrosomal protein 55 like.	Nucleolar and spindle associated protein 1.	0.886
cep55	pbk	ENSCVAP00000019303	ENSCVAP00000032058	Centrosomal protein 55 like.	PDZ binding kinase.	0.904
kif4a	cep55	ENSCVAP00000024864	ENSCVAP00000019303	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Centrosomal protein 55 like.	0.843
kif4a	melk	ENSCVAP00000024864	ENSCVAP00000016448	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Non-specific serine/threonine protein kinase.	0.928
kif4a	nusap1	ENSCVAP00000024864	ENSCVAP00000018926	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Nucleolar and spindle associated protein 1.	0.879
kif4a	pbk	ENSCVAP00000024864	ENSCVAP00000032058	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	PDZ binding kinase.	0.884
melk	cep55	ENSCVAP00000016448	ENSCVAP00000019303	Non-specific serine/threonine protein kinase.	Centrosomal protein 55 like.	0.841
melk	kif4a	ENSCVAP00000016448	ENSCVAP00000024864	Non-specific serine/threonine protein kinase.	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.928
melk	nusap1	ENSCVAP00000016448	ENSCVAP00000018926	Non-specific serine/threonine protein kinase.	Nucleolar and spindle associated protein 1.	0.885
melk	pbk	ENSCVAP00000016448	ENSCVAP00000032058	Non-specific serine/threonine protein kinase.	PDZ binding kinase.	0.922
nusap1	cep55	ENSCVAP00000018926	ENSCVAP00000019303	Nucleolar and spindle associated protein 1.	Centrosomal protein 55 like.	0.886
nusap1	kif4a	ENSCVAP00000018926	ENSCVAP00000024864	Nucleolar and spindle associated protein 1.	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.879
nusap1	melk	ENSCVAP00000018926	ENSCVAP00000016448	Nucleolar and spindle associated protein 1.	Non-specific serine/threonine protein kinase.	0.885
nusap1	pbk	ENSCVAP00000018926	ENSCVAP00000032058	Nucleolar and spindle associated protein 1.	PDZ binding kinase.	0.920
pbk	cep55	ENSCVAP00000032058	ENSCVAP00000019303	PDZ binding kinase.	Centrosomal protein 55 like.	0.904
pbk	kif4a	ENSCVAP00000032058	ENSCVAP00000024864	PDZ binding kinase.	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.884
pbk	melk	ENSCVAP00000032058	ENSCVAP00000016448	PDZ binding kinase.	Non-specific serine/threonine protein kinase.	0.922
pbk	nusap1	ENSCVAP00000032058	ENSCVAP00000018926	PDZ binding kinase.	Nucleolar and spindle associated protein 1.	0.920